Results 301 to 310 of about 1,676,612 (335)

Laminopathies : the nuclear lamina alteration

, 2015
Mir Pérez, Cristina, Universitat Autònoma de Barcelona. Facultat de Biociències   +1 more
openaire   +1 more source

Zinc Alleviates Gut Barrier Dysfunction by Promoting the Methylation of AKT

Advanced Science, EarlyView.
Zinc activates the ZNG1‐METAP1 complex to elevate intracellular SAM levels, which promotes PRMT5‐mediated symmetrical dimethylation of AKT at R391 and R15. This epigenetic modification facilitates AKT membrane translocation and mTORC2 activation, thereby enhancing epithelial proliferation and gut barrier integrity.
Chuanjiang Cai, Yining Zheng, Bo Sun, Guoyan Wang, Pengfei Li, Huijun Geng, Rongnuo Li, Miaomiao Zhu, Yuanyuan Zhu, Dingping Feng, Lei Chen, Guiyan Chu, Lu Deng, Shiyan Qiao   +13 more
wiley   +1 more source

In Situ Formation of Mechanically Interlocked Heterointerfaces with Ultrahigh Bonding Strength for Mg‐Based Multilayered Sheets

Advanced Science, EarlyView.
Crystal‐orientation controlled hot‐rolling strategy creates Mg‐Ta immiscible composites featuring mechanically interlocked in situ formed interfaces (80.5 MPa bond strength) and excellent tensile properties (340–395 MPa UTS). Systematic multiscale investigations reveal a serration‐size‐dependent bonding mechanism and a three‐stage interfacial evolution
Zhilei Yu, Wenbo Luo, Wei Xue, Rongqin Xu, Xiuzhu Han, Zhiyong Xue, Wanshun Zhang, Hongyang Zhao, Xiaoming Cui   +8 more
wiley   +1 more source

A Shape‐Adaptive, Performance‐Programmable, Self‐Healable and On‐Demand Destructible Robotic Skin via Self‐Strengthening Dynamic Silicone

Advanced Science, EarlyView.
Enabled by the distinctive inter‐ and intra‐chain siloxane exchange in commercially available silicones as the dielectric layer, the omni‐adaptive robotic skin (OmniAdapt) integrates multiple advanced functionalities: programmable sensing performance via the self‐stiffening dielectric material, application as BPM sensor, shape adaptivity for electronic
Wusha Miao, Lara S. Laamari, Jing Yu, Sanjay Schreiber, Lukas Heer, Jiacheng Cui, Jiayuan Huang, Hedan Bai   +7 more
wiley   +1 more source

Homogeneously‐Dimensionalizing Perovskite Surface by Dual‐Mechano‐Chemical Regulation for Efficient Solar Cells

Advanced Science, EarlyView.
A homogeneous and strengthened 2D/3D perovskite heterointerface is realized by idealizing the perovskite surface to eliminate atomic‐scale impurities and micro‐wrinkles. Benefiting from the reinforcement of charge transfer and lattice solidification, an all‐air‐processed carbon‐based all‐inorganic CsPbI2Br device achieves an enhanced efficiency of 15 ...
Shengwei Geng, Jialong Duan, Chenlong Zhang, Jinyue Zhang, Yueyang Bi, Yueji Liu, Xixi Zhu, Xinyu Zhang, Qiyao Guo, Jie Dou, Benlin He, Yuanyuan Zhao, Qunwei Tang   +12 more
wiley   +1 more source

Ionic Double‐Network Hydrogels for Integrated Electromagnetic Shielding and Self‐Powered Sensing in Wearable Electronics

Advanced Science, EarlyView.
A multifunctional dual network ionic hydrogel is used to address the challenges of EMI and health detection integration for CIEDs. An absorption‐based EMI shielding mechanism is achieved through ion polarization/interfacial relaxation. With an optimal SE of 63.75 dB and absorption loss greater than 93%, the wirelessly integrated self‐powered sensor in ...
Chenchen Wang, Yao Ding, Tianzhao Wu, Zihua Li, Chuanshuang Hu, Zhuoqun Wang, Yonghui Zhou, Xiuyi Lin, Weiwei Zhang, Jiangtao Xu   +9 more
wiley   +1 more source

Carbon‐Coated Probiotics Restore Intestinal Homeostasis to Promote Damage Repair in Inflammatory Bowel Disease

Advanced Science, EarlyView.
Carbon‐coated Lactobacillus rhamnosus GG (C dots@LGG) enhances the antioxidant effects of LGG and safeguards the probiotics to target the inflamed colon. This reduces inflammation and oxidative damage, repairs the intestinal barrier, regulates the microbiota, and alleviates colitis.
Xue Chen, Haiyan Guo, Yuhan Li, Qiaowen Lin, Hua Liu, Liwen Hong, Lei Wang, Jie Zhong, Dalong Ni, Zhengting Wang   +9 more
wiley   +1 more source

MXene‐Integrated Printed Piezoresistive Flexible Sensors: A Breakthrough in Real‐Time Monitoring for Medical and Smart Applications

Advanced Science, EarlyView.
A chocolate‐inlaid Ag@waffle‐structured MXene is synthesized in this research via template‐directed growth strategy (WSM‐A8). The pressure sensor prepared with the WSM‐A8 presents the highest ΔI/I0 response intensity among the reported MXene‐based piezoresistive sensors with satisfactory sensitivity, outstanding structural stability, and superior ...
Hao‐wen Zhang, Xiang Xu, Di‐wen Jiang, Jie Lu, Yang‐sheng Wang, Zhe‐sheng Feng, Yan Wang   +6 more
wiley   +1 more source

Exploring Nuclear Lamina Structure and Lamin Dissociation in Progeria through Polymer Modeling

Hadiya Abdul Hameed, Jarosław Paturej, Aykut Erbaş   +2 more
openalex   +1 more source

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Functional mechanisms and abnormalities of the nuclear lamina

Nature Cell Biology, 2021
Alterations in nuclear shape are present in human diseases and ageing. A compromised nuclear lamina is molecularly interlinked to altered chromatin functions and genomic instability. Whether these alterations are a cause or a consequence of the pathological state are important questions in biology.
Adam Karoutas, A. Akhtar
semanticscholar   +5 more sources