Results 41 to 50 of about 332,213 (303)

Nuclear transport signals control cellular localization and function of androgen receptor cofactor p44/WDR77.

open access: yesPLoS ONE, 2011
The androgen receptor (AR) cofactor p44/WDR77, which regulates expression of a set of androgen target genes, is required for differentiation of prostate epithelium.
Zhongping Gu   +3 more
doaj   +1 more source

A conserved C-terminal domain of the Aspergillus fumigatus developmental regulator MedA is required for nuclear localization, adhesion and virulence. [PDF]

open access: yesPLoS ONE, 2012
MedA is a developmental regulator that is conserved in the genome of most filamentous fungi. In the pathogenic fungus Aspergillus fumigatus MedA regulates conidiogenesis, adherence to host cells, and pathogenicity.
Qusai Al Abdallah   +6 more
doaj   +1 more source

Identification of a novel nuclear localization signal sequence in Chlamydia trachomatis-secreted hypothetical protein CT311. [PDF]

open access: yesPLoS ONE, 2013
We previously reported that Chlamydia trachomatis hypothetical protein CT311 was secreted out of chlamydial inclusion and into host cell cytosol. We now found that CT311 further entered host cell nucleus at the late stage of infection and continued to ...
Lei Lei   +3 more
doaj   +1 more source

Nuclear localization signal peptides (NLS) and their role in viral pathogenicity

open access: yesAnnals of Mechnikov's Institute, 2020
The review provides data about nuclear localization signal peptides (NLS) and their function in the cell, incl. with a viral infection process. The binding, penetration, assembly, and budding of viruses are currently being intensively studied in many ...
Tatiana Nikolaevna Nosalskaya   +2 more
doaj   +3 more sources

Nucleolar localization of influenza A NS1: striking differences between mammalian and avian cells [PDF]

open access: yes, 2010
In mammalian cells, nucleolar localization of influenza A NS1 requires the presence of a C-terminal nucleolar localization signal. This nucleolar localization signal is present only in certain strains of influenza A viruses.
Soubies, S.M.   +18 more
core   +1 more source

Functional domains of SP110 that modulate its transcriptional regulatory function and cellular translocation

open access: yesJournal of Biomedical Science, 2018
Background SP110, an interferon-induced nuclear protein, belongs to the SP100/SP140 protein family. Very recently, we showed that SP110b, an SP110 isoform, controls host innate immunity to Mycobacterium tuberculosis infection by regulating nuclear factor-
Jia-Shiun Leu   +4 more
doaj   +1 more source

Data for: Nuclear localization signal regulates Porcine Circovirus type 2 Capsid protein nuclear export through phosphorylation

open access: yes, 2018
Data for: Nuclear localization signal regulates Porcine Circovirus type 2 Capsid protein nuclear export through ...
Xiaoyu Guo (280620)   +7 more
core   +2 more sources

Coordinate nuclear targeting of the FANCD2 and FANCI proteins via a FANCD2 nuclear localization signal. [PDF]

open access: yesPLoS ONE, 2013
Fanconi anemia (FA) is a rare recessive disease, characterized by congenital defects, bone marrow failure, and increased cancer susceptibility. FA is caused by biallelic mutation of any one of sixteen genes.
Rebecca A Boisvert   +4 more
doaj   +1 more source

Pentapeptide Nuclear Localization Signal in Adenovirus E1a [PDF]

open access: yesMolecular and Cellular Biology, 1987
The adenovirus E1a gene products are nuclear proteins important in transcriptional control of viral functions during infection. By producing normal E1a proteins and derivatives of E1a in bacteria and microinjecting these proteins into cultured cells, we were able to examine their ability to localize to the nucleus.
R H, Lyons, B Q, Ferguson, M, Rosenberg
openaire   +2 more sources

Characterization of the Nucleocytoplasmic Transport Mechanisms of Epstein-Barr Virus BFLF2

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Epstein-Barr virus (EBV) BFLF2, the homologue of herpes simplex virus 1 (HSV-1) UL31, is crucial for the efficient viral DNA packaging and primary egress across the nuclear membrane.
Meili Li   +11 more
doaj   +1 more source

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