Results 1 to 10 of about 395,400 (125)

Cervicocephalic Spotty Calcium for the Prediction of Coronary Atherosclerosis in Patients With Acute Ischemic Stroke

open access: yesFrontiers in Neurology, 2021
Purpose: To investigate the characteristics of cervicocephalic spotty calcium (SC) and coronary atherosclerosis in patients with acute ischemic stroke (AIS) and to assess the predictive value of SC for coronary atherosclerosis using combined coronary and
Chong Zheng   +13 more
doaj   +1 more source

Comparison of Image Quality and Radiation Dose Between Single-Energy and Dual-Energy Images for the Brain With Stereotactic Frames on Dual-Energy Cerebral CT

open access: yesFrontiers in Radiology, 2022
BackgroundPreoperative stereotactic planning of deep brain stimulation (DBS) using computed tomography (CT) imaging in patients with Parkinson's disease (PD) is of clinical interest. However, frame-induced metal artifacts are common in clinical practice,
Xiaojing Zhao   +13 more
doaj   +1 more source

The DNA Recognition Motif of GapR Has an Intrinsic DNA Binding Preference towards AT-rich DNA

open access: yesMolecules, 2021
The nucleoid-associated protein GapR found in Caulobacter crescentus is crucial for DNA replication, transcription, and cell division. Associated with overtwisted DNA in front of replication forks and the 3′ end of highly-expressed genes, GapR can ...
Qian Huang   +4 more
doaj   +1 more source

Contrasting Properties of Polymeric Nanocarriers for MRI-Guided Drug Delivery

open access: yesNanomaterials, 2023
Poor pharmacokinetics and low aqueous solubility combined with rapid clearance from the circulation of drugs result in their limited effectiveness and generally high therapeutic doses.
Natalia Łopuszyńska   +1 more
doaj   +1 more source

Distinct activation mechanisms of β-arrestin-1 revealed by 19F NMR spectroscopy

open access: yesNature Communications, 2023
β-Arrestins (βarrs) are functionally versatile proteins that play critical roles in the G-protein-coupled receptor (GPCR) signaling pathways. While it is well established that the phosphorylated receptor tail plays a central role in βarr activation ...
Ruibo Zhai   +6 more
doaj   +1 more source

Design, Characterization and Molecular Modeling of New Fluorinated Paramagnetic Contrast Agents for Dual 1H/19F MRI

open access: yesMagnetochemistry, 2020
One major goal in medical imaging is the elaboration of more efficient contrast agents (CAs). Those agents need to be optimized for the detection of affected tissues such as cancers or tumors while decreasing the injected quantity of agents.
Emilie Hequet   +8 more
doaj   +1 more source

Predictive value of baseline metabolic tumor burden on 18F-FDG PET/CT for brain metastases in patients with locally advanced non-small-cell lung cancer

open access: yesFrontiers in Oncology, 2022
ObjectivesBrain metastases (BMs) are a major cause leading to the failure of treatment management for non-small-cell lung cancer (NSCLC) patients. The purpose of this study was to evaluate the predictive value of baseline metabolic tumor burden on 18F ...
Jingjie Shang   +9 more
doaj   +1 more source

Variations of Brain Functional Connectivity in Alcohol-Preferring and Non-Preferring Rats with Consecutive Alcohol Training or Acute Alcohol Administration

open access: yesBrain Sciences, 2021
Alcohol addiction is regarded as a series of dynamic changes to neural circuitries. A comparison of the global network during different stages of alcohol addiction could provide an efficient way to understand the neurobiological basis of addiction.
Yue Liu   +10 more
doaj   +1 more source

Preoperative prediction of Lauren classification in gastric cancer: a radiomics model based on dual-energy CT iodine map

open access: yesInsights into Imaging, 2023
Objective To investigate the value of a radiomics model based on dual-energy computed tomography (DECT) venous-phase iodine map (IM) and 120 kVp equivalent mixed images (MIX) in predicting the Lauren classification of gastric cancer.
Min Li   +7 more
doaj   +1 more source

Morphological feature and mapping inflammation in classified carotid plaques in symptomatic and asymptomatic patients: A hybrid 18F-FDG PET/MR study

open access: yesFrontiers in Neuroscience, 2023
PurposeTo investigate morphological and inflamed-metabolism features of carotid atherosclerotic plaques between symptomatic and asymptomatic patients with hybrid 18F-FDG PET/MR imaging.MethodsA total of 20 symptomatic and 20 asymptomatic patients with ...
Yue Zhang   +15 more
doaj   +1 more source

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