Results 1 to 10 of about 1,126,315 (245)

Review and Prospect: Deep Learning in Nuclear Magnetic Resonance Spectroscopy [PDF]

Chemistry, 2020
Since the concept of Deep Learning (DL) was formally proposed in 2006, it had a major impact on academic research and industry. Nowadays, DL provides an unprecedented way to analyze and process data with demonstrated great results in computer vision ...
Dicheng Chen, Zi Wang, D. Guo, V. Orekhov, X. Qu   +4 more
semanticscholar   +1 more source

Comparison of Image Quality and Radiation Dose Between Single-Energy and Dual-Energy Images for the Brain With Stereotactic Frames on Dual-Energy Cerebral CT

Frontiers in Radiology, 2022
BackgroundPreoperative stereotactic planning of deep brain stimulation (DBS) using computed tomography (CT) imaging in patients with Parkinson's disease (PD) is of clinical interest. However, frame-induced metal artifacts are common in clinical practice,
Xiaojing Zhao, Xiaojing Zhao, Wang Chao, Wang Chao, Yi Shan, Yi Shan, Jingkai Li, Jingkai Li, Cheng Zhao, Cheng Zhao, Miao Zhang, Miao Zhang, Jie Lu, Jie Lu   +13 more
doaj   +1 more source

Cervicocephalic Spotty Calcium for the Prediction of Coronary Atherosclerosis in Patients With Acute Ischemic Stroke

Frontiers in Neurology, 2021
Purpose: To investigate the characteristics of cervicocephalic spotty calcium (SC) and coronary atherosclerosis in patients with acute ischemic stroke (AIS) and to assess the predictive value of SC for coronary atherosclerosis using combined coronary and
Chong Zheng, Chong Zheng, Shaozhen Yan, Shaozhen Yan, Fan Fu, Fan Fu, Cheng Zhao, Cheng Zhao, Daode Guo, Daode Guo, Zhichao Wang, Zhichao Wang, Jie Lu, Jie Lu   +13 more
doaj   +1 more source

The DNA Recognition Motif of GapR Has an Intrinsic DNA Binding Preference towards AT-rich DNA

Molecules, 2021
The nucleoid-associated protein GapR found in Caulobacter crescentus is crucial for DNA replication, transcription, and cell division. Associated with overtwisted DNA in front of replication forks and the 3′ end of highly-expressed genes, GapR can ...
Qian Huang, Bo Duan, Zhi Qu, Shilong Fan, Bin Xia   +4 more
doaj   +1 more source

Contrasting Properties of Polymeric Nanocarriers for MRI-Guided Drug Delivery

Nanomaterials, 2023
Poor pharmacokinetics and low aqueous solubility combined with rapid clearance from the circulation of drugs result in their limited effectiveness and generally high therapeutic doses.
Natalia Łopuszyńska, Władysław P. Węglarz   +1 more
doaj   +1 more source

Distinct activation mechanisms of β-arrestin-1 revealed by 19F NMR spectroscopy

Nature Communications, 2023
β-Arrestins (βarrs) are functionally versatile proteins that play critical roles in the G-protein-coupled receptor (GPCR) signaling pathways. While it is well established that the phosphorylated receptor tail plays a central role in βarr activation ...
Ruibo Zhai, Zhuoqi Wang, Zhaofei Chai, Xiaogang Niu, Conggang Li, Changwen Jin, Yunfei Hu   +6 more
doaj   +1 more source

Predictive value of baseline metabolic tumor burden on 18F-FDG PET/CT for brain metastases in patients with locally advanced non-small-cell lung cancer

Frontiers in Oncology, 2022
ObjectivesBrain metastases (BMs) are a major cause leading to the failure of treatment management for non-small-cell lung cancer (NSCLC) patients. The purpose of this study was to evaluate the predictive value of baseline metabolic tumor burden on 18F ...
Jingjie Shang, Huimin You, Chenchen Dong, Yingxin Li, Yong Cheng, Yongjin Tang, Bin Guo, Jian Gong, Xueying Ling, Hao Xu   +9 more
doaj   +1 more source

Design, Characterization and Molecular Modeling of New Fluorinated Paramagnetic Contrast Agents for Dual ¹H/¹⁹F MRI

Magnetochemistry, 2020
One major goal in medical imaging is the elaboration of more efficient contrast agents (CAs). Those agents need to be optimized for the detection of affected tissues such as cancers or tumors while decreasing the injected quantity of agents.
Emilie Hequet, Céline Henoumont, Vera Djouana Kenfack, Vincent Lemaur, Roberto Lazzaroni, Sébastien Boutry, Luce Vander Elst, Robert N. Muller, Sophie Laurent   +8 more
doaj   +1 more source

Accelerated Nuclear Magnetic Resonance Spectroscopy with Deep Learning [PDF]

Angewandte Chemie, 2019
Nuclear magnetic resonance (NMR) spectroscopy serves as an indispensable tool in chemistry and biology but often suffers from long experimental time.
X. Qu, Yihui Huang, Hengfa Lu, Tianyu Qiu, D. Guo, V. Orekhov, Zhong Chen   +6 more
semanticscholar   +1 more source

Constraints on bosonic dark matter from ultralow-field nuclear magnetic resonance [PDF]

Science Advances, 2019
CASPEr-ZULF offers a new way to search for ultralight dark matter using ultralow-field nuclear magnetic resonance. The nature of dark matter, the invisible substance making up over 80% of the matter in the universe, is one of the most fundamental ...
Antoine Garcon, J. Blanchard, Gary P. Centers, N. L. Figueroa, P. Graham, Derek F. Jackson Kimball, S. Rajendran, A. Sushkov, Y. Stadnik, A. Wickenbrock, Teng Wu, D. Budker   +11 more
semanticscholar   +1 more source