Results 31 to 40 of about 1,135,294 (342)
DNA binding mechanism of WhiB4 from Mycobacterium tuberculosis
Mycobacterium tuberculosis (Mtb), the pathogen of tuberculosis, has latently infected about one-third of the world's population and may lead to severe clinical symptoms and death.
Qiran Zhai+5 more
doaj +1 more source
Biological Magnetic Resonance Data Bank
The Biological Magnetic Resonance Data Bank (BMRB, https://bmrb.io) is the international open data repository for biomolecular nuclear magnetic resonance (NMR) data.
J. Hoch+15 more
semanticscholar +1 more source
Determination of Apparent Protein Molecular Weight in Solution by Diffusion Ordered NMR Spectroscopy
Diffusion ordered NMR spectroscopy (DOSY) can be used to determine the apparent molecular weight of proteins (Mprotein) by measuring self-diffusion coefficient (Dt-protein).
LI Hong-wei, YUAN Zhi-liang, XIA Bin
doaj +1 more source
The new magnetic system construction and the registration circuit of the nuclear magnetic resonance signal in the weak magnetic field are considered.
N. Myazin+3 more
semanticscholar +1 more source
Nuclear magnetic resonance (NMR) spectroscopy is a powerful analytical technique with a wide variety of applications, from structural elucidation of complex molecules, to 3D-imaging of fresh tissue, to simple ingredient assays for quality assurance. NMR differs from most other forms of spectroscopy because the nucleus is the subject of analysis and the
Bradley L. Reuhs, Senay Simsek
openaire +2 more sources
Function and dynamics of the intrinsically disordered carboxyl terminus of β2 adrenergic receptor
Advances in structural biology have provided important mechanistic insights into signaling by the transmembrane core of G-protein coupled receptors (GPCRs); however, much less is known about intrinsically disordered regions such as the carboxyl terminus (
Jie Heng+19 more
doaj +1 more source
Tight oil sandstones have the characteristics of narrow pore throats, complex pore structures and strong heterogeneities.
Fuyong Wang, Kun Yang, Jianchao Cai
semanticscholar +1 more source
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter+8 more
wiley +1 more source
Multimodal CT Imaging Characteristics in Predicting Prognosis of Wake-Up Stroke
Background: Multimodal CT imaging can evaluate cerebral hemodynamics and stroke etiology, playing an important role in predicting prognosis. This study aimed to summarize the comprehensive image characteristics of wake-up stroke (WUS), and to explore its
Fan Yu+18 more
doaj +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source