Results 211 to 220 of about 516,029 (259)
The nuclear matrix and apoptosis [PDF]
Histochemistry and Cell Biology, 1997 Apoptosis is a form of active cell death, genetically encoded, that plays a key role during several physiological and pathological conditions. During the apoptotic process, striking morphological and biochemical changes take place in the cell nucleus. However, the molecular mechanisms underlying these changes have escaped clarification for many years ...
Martelli A. M. +5 more
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Nuclear Domains and the Nuclear Matrix
1996This overview describes the spatial distribution of several enzymatic machineries and functions in the interphase nucleus. Three general observations can be made. First, many components of the different nuclear machineries are distributed in the nucleus in a characteristic way for each component.
R, van Driel +5 more
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Nuclear factor 1 is a component of the nuclear matrix
Journal of Cellular Biochemistry, 1994AbstractChicken histone H5 is an H1‐like linker histone that is expressed only in nucleated erythrocytes. The histone H5 promoter has binding sites for Sp1 (a high affinity site) and UPE‐binding protein, while the 3′ erythroid‐specific enhancer has binding sites for Sp1 (one moderate and three weak affinity), GATA‐1, and NF1.
J M, Sun, H Y, Chen, J R, Davie
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Nuclear envelope and nuclear matrix: interactions and dynamics
Cellular and Molecular Life Sciences, 2001The peripheral nuclear lamina is located near the nuclear inner membrane and consists of lamin filaments and integral membrane proteins, including the lamin B receptor and various isoforms of lamina-associated polypeptides (LAP) 1 and 2. Several nuclear membrane proteins also interact with chromatin proteins BAF and Hp1.
S, Vlcek, T, Dechat, R, Foisner
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The nuclear matrix in pathology
Virchows Archiv, 1999For a long time the molecular basis of nuclear structure has been a matter of debate rather than an established fact. In the last decade the concept of the nuclear matrix has emerged, and the molecular basis of this nuclear infrastructure, although still incomplete, is gradually being unravelled.
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The nuclear matrix: Structure and composition
Journal of Cell Science, 1988ABSTRACT The term nuclear matrix was first introduced by Berezney & Coffey (1974) to denote a highly structured residual framework obtained from rat liver nuclei by sequential salt extractions, detergent and nuclease treatments. The isolated three-dimensional structure consisted almost entirely of protein.
R, Verheijen +2 more
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Nuclear localization of Matrix metalloproteinases
Progress in Histochemistry and Cytochemistry, 2012Matrix metalloproteinases (MMPs) were originally identified as matrixin proteases that act in the extracellular matrix. Recent works have uncovered nontraditional roles for MMPs in the extracellular space as well as in the cytosol and nucleus. There is strong evidence that subspecialized and compartmentalized matrixins participate in many physiological
MANNELLO, FERDINANDO, V. Medda
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Unravelling the nuclear matrix proteome
Journal of Proteomics, 2009The nuclear matrix (NM) model posits the presence of a protein/RNA scaffold that spans the mammalian nucleus. The NM proteins are involved in basic nuclear function and are a promising source of protein biomarkers for cancer. Importantly, the NM proteome is operationally defined as the proteins from cells and tissue that are extracted following a ...
Albrethsen, J. +2 more
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Identification of a nuclear protein matrix
Biochemical and Biophysical Research Communications, 1974Abstract The structural framework of the rat liver nucleus has been identified and consists of a nuclear protein matrix. This matrix is 98.4% protein, 0.1% DNA, 1.2% RNA, and 0.5% phospholipid. The nuclear protein matrix is composed primarily of three acidic polypeptide fractions in the molecular weight range of 60–70,000 daltons.
R, Berezney, D S, Coffey
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The Nuclear Matrix and Virus Function
1996Replication of the small DNA tumor virus, simian virus 40 (SV40), is largely dependent on host cell functions, because SV40, in addition to virion proteins, codes only for a few regulatory proteins, the most important one being the SV40 large tumor antigen (T-antigen).
W, Deppert, R, Schirmbeck
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