Results 31 to 40 of about 516,029 (259)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
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Closed-form Brückner G-matrix and nuclear matter in EFT(π̸)
Physics Letters B, 2021 The closed-form Brückner G matrix for nuclear matter is computed in the S01 channel of EFT(π̸) and renormalized in nonperturbative context. The nuclear medium environment yields additional constraints that are consistent with off-shell T matrix ...
Ting-Wei Pan, Ji-Feng Yang
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Frontiers in Molecular BiosciencesThe hierarchical structure of eukaryotic genomes has regulatory layers, one of them being epigenetic “indexing” of the genome that leads to cell-type-specific patterns of gene expression.
Rashmi Upadhyay Pathak +4 more
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
An Overview to the Structure and Function of Nuclear Matrix [PDF]
Cell Journal, 2009 Although the genome is defined by its primary sequence, its functional properties, aredetermined by far more complex mechanisms and depend on multiple layers of nuclearorganization. The architecture of the nucleus includes two overlapping structures: the
M. Shahhoseini, A. Rabbani Chadegani
doaj
Coordination of matrix attachment and ATP-dependent chromatin remodeling regulate auxin biosynthesis and Arabidopsis hypocotyl elongation. [PDF]
PLoS ONE, 2017 Hypocotyl elongation is extensively controlled by hormone signaling networks. In particular, auxin metabolism and signaling play key roles in light-dependent hypocotyl growth.
Kyounghee Lee, Pil Joon Seo
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Modification of nuclear matrix proteins by ADP‐ribosylation [PDF]
European Journal of Biochemistry, 1985 Nuclear matrices were isolated by treatment of isolated HeLa cell nuclei with high DNase I, pancreatic RNase and salt concentrations. ADP‐ribosylated nuclear matrix proteins were identified by electrophoresis, blotting and autoradiography.In one experimental approach nuclear matrix proteins were labeled by exposure of permeabilized cells to the labeled
J, Wesierska-Gadek, G, Sauermann
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
On the history of nuclear matrix manifestation [PDF]
Cell Research, 1998 The nonchromatin proteinous residue of the cell nucleus was revealed in our laboratory as early as in 1948 and then identified by light and electron microscopy as residual nucleoli, intranuclear network and nuclear envelope before 1960. This structure termed afterwards as "nuclear residue", "nuclear skeleton", "nuclear cage", "nuclear carcass" etc ...
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