Results 251 to 260 of about 809,360 (285)

Nuclear morphology during the S phase

Microscopy Research and Technique, 1998
In order to evaluate at the ultrastructural level the chromatin arrangement during the S phase of the cell cycle, the detection of Bromodeoxyuridine (BrdU) by immunogold has been performed in synchronized 3T3 fibroblasts, regenerating liver, and Friend Leukemia Cells (FLC).
MAZZOTTI G, GOBBI, PIETRO, MANZOLI L, FALCONI M.   +3 more
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Freeze-fracture morphology of nuclear pockets

Virchows Archiv B Cell Pathology Including Molecular Pathology, 1991
Nuclear pockets (NP) are found in numerous human tumours and in certain non-neoplastic cells. This study concerns the structure of NP in cells from two malignant rhabdoid tumours, one embryonal rhabdomyosarcoma, two centroblastic/centrocytic lymphomas, one centrocytic lymphoma and one Ki-1 lymphoma, as well as in normal neutrophils.
E, Kaiserling, H, Wolburg
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Nuclear Morphology of Human Spermatozoa

Nature, 1960
THIS communication concerns observations on dried, unstained smears of human spermatozoa in phase contrast. These were made in an attempt to gain more insight into the basis for the known differential in conception and birth sex ratios.
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p300 Modulates Nuclear Morphology in Prostate Cancer

Cancer Research, 2005
Abstract Alterations in nuclear structure distinguish cancer cells from noncancer cells. These nuclear alterations can be translated into quantifiable features by digital image analysis in a process known as quantitative nuclear morphometry.
Jose D, Debes, Thomas J, Sebo, Hannelore V, Heemers, Benjamin R, Kipp, De Anna L, Haugen, Christine M, Lohse, Donald J, Tindall   +6 more
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Mathematical model of nuclear speckle morphology

2023
Nuclear speckles are nuclear bodies consisting of populations of small and irregularly shaped droplet-like molecular condensates that contain various splicing factors. Recent experiments have shown the following morphological features of nuclear speckles: (I) Each molecular condensate contains SON and SRRM2 proteins, andMALAT1 non-coding RNA surrounds ...
Shingo Wakao, Noriko Saitoh, Akinori Awazu   +2 more
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Nuclear morphology of yeast under thymidylate starvation

Chromosoma, 1981
During early meiotic development the yeast Saccharomyces cerevisiae has a characteristic nuclear dense body (NDB). It is shown that the NDB can also be induced in vegetatively growing cells through the inhibition of thymidylate synthetase which causes depletion of the dTMP pool and arrests DNA synthesis.
P B, Moens, B J, Barclay, J G, Little
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Glomerulosomes: morphologically distinct nuclear organelles of unknown nature

Protoplasma, 2022
The nucleus of some representatives of the genus Pelomyxa (Amoebozoa, Archamoebae, Pelobiontida) contains specific bodies (membrane-less organelles). They may be either embedded in the nucleolar mass or detached from the nucleolus. We termed these nuclear bodies the glomerulosomes for their characteristic ultrastructural appearance.
Dmitry S. Bogolyubov, Lyudmila V. Chistyakova, Andrew V. Goodkov   +2 more
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Macrophage and epithelioid cell nuclear morphology in leprosy

Pathology - Research and Practice, 1992
The spectrum of disease in leprosy is characterised by the presence of macrophages in lepromatous lesions and epithelioid cells in tuberculoid granulomas. Since changes in nuclear shape occur during macrophage activation, we have measured nuclear morphology by planimetry in biopsies across the leprosy spectrum.
G, Campbell, I A, Cree
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Cytoskeletal Control of Nuclear Morphology and Chromatin Organization

Journal of Molecular Biology, 2015
The nucleus is sculpted toward various morphologies during cellular differentiation and development. Alterations in nuclear shape often result in changes to chromatin organization and genome function. This is thought to be reflective of its role as a cellular mechanotransducer. Recent evidence has highlighted the importance of cytoskeletal organization
Nisha M, Ramdas, G V, Shivashankar
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Nuclear Morphology and Grading in Tumours

1990
von Hansemann (1890) is credited with first postulating that abnormalities of nuclear morphology in tumour cells might be correlated with their biological properties and clinical behaviour. He placed importance on the mitotic rate and the presence of abnormal mitoses (von Hansemann 1892).
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