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The composition and morphology of yeast nuclear scaffolds

Journal of Cell Science, 1990
ABSTRACT The yeast nuclear scaffold has been shown to bind with high affinity to genomic sequences that permit autonomous DNA replication of plasmids (ARS elements). We describe here conditions for the isolation of a histone-free nuclear substructure, the nuclear scaffold, from Saccharomyces cerevisiae. We examine the protein composition
M E, Cardenas, T, Laroche, S M, Gasser
openaire   +2 more sources

Lipid-dependent nuclear signalling: Morphological and functional features

Advances in Enzyme Regulation, 1994
Enzymes involved in lipid metabolism exist within the nucleus and are responsive to external stimuli. In particular, the kinases which phosphorylate phosphatidylinositol and phosphatidylinositol-4-monophosphate have been demonstrated in nuclei of both undifferentiated and differentiated Friend cells and of quiescent Swiss 3T3 cells as well as of those ...
N M, Maraldi   +5 more
openaire   +2 more sources

Constructing polymorphonuclear cells: chromatin folding shapes nuclear morphology

Trends in Immunology
Immune cell fate decisions are regulated, at least in part, by nuclear architecture. Here, we outline how nuclear architecture instructs mammalian polymorphonuclear cell differentiation. We discuss how in neutrophils loop extrusion mechanisms regulate the expression of genes involved in phagocytosis and shape nuclear morphology.
Cornelis, Murre   +3 more
openaire   +2 more sources

Molecular imaging in oncology: Current impact and future directions

Ca-A Cancer Journal for Clinicians, 2022
Steven P Rowe, Martin G Pomper
exaly  

Mechanics and functional consequences of nuclear deformations

Nature Reviews Molecular Cell Biology, 2022
Andrew D Stephens   +2 more
exaly  

Deterioration of nuclear morphology and architecture: A hallmark of senescence and aging

Ageing Research Reviews, 2021
Rashmi Pathak   +2 more
exaly  

Transcriptional control of energy metabolism by nuclear receptors

Nature Reviews Molecular Cell Biology, 2022
Charlotte Scholtes, Vincent Giguère
exaly  

The nuclear envelope environment and its cancer connections

Nature Reviews Cancer, 2012
Katharine S Ullman
exaly  

Mechanisms and functions of nuclear envelope remodelling

Nature Reviews Molecular Cell Biology, 2017
Ulrike Kutay
exaly  

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