Results 81 to 90 of about 2,490,880 (360)
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Penning-Trap Mass Measurements in Atomic and Nuclear Physics
Annual Review of Nuclear and Particle Science, 2018 Penning-trap mass spectrometry in atomic and nuclear physics has become a well-established and reliable tool for the determination of atomic masses. In combination with short-lived radioactive nuclides it was first introduced at ISOLTRAP at the Isotope ...
J. Dilling +3 more
semanticscholar +1 more source
Whither Nuclear Physics? [PDF]
, 2009 Nuclear Physics has had its ups and downs. However in recent years, bucked up by some new and often puzzling data, it has become a potentially very rich field. We review some of these exciting developments in a few important sectors of nuclear physics. Emphasis shall be on the study of exotic nuclei and the new physics that these nuclei are teaching us.
openaire +3 more sources
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To identify metabolic patterns in the brain and musculoskeletal system of stiff person syndrome spectrum disorders (SPSD) patients over time using PET imaging and evaluate the impact of immune therapy on metabolic activity as a surrogate for treatment response.
Munther M. Queisi +4 more
wiley +1 more source
Application of Atomic Spectroscopy of Trapped Radioactive Ions in Nuclear Physics
AtomsA review is given of precision measurements of hyperfine constants and nuclear g-factors measured with ions confined in ion traps. The nuclear physics observables which can be extracted from these types of measurements are discussed.
Ruben P. de Groote
doaj +1 more source
Assessing a Mitochondrial Disease Treatment via a Novel Statistical Technique for Accelerometer Data
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Therapeutic development for mitochondrial diseases, rare genetic disorders with pathogenic defects of oxidative phosphorylation, is hindered by unsatisfactory outcome measures. To address this problem, we provide the first clinical application of a novel, bias‐adjusted outcome measure of acceleration across a range of subjects ...
Ian W. McKeague +8 more
wiley +1 more source
Tracking Detectors in Low-Energy Nuclear Physics: An Overview
Quantum Beam ScienceAdvances in accelerator technology have enabled the use of exotic and intense radioactive ion beams. Enhancements to tracking detectors are necessary to accommodate increased particle rates.
Jelena Vesić
doaj +1 more source
An Outlook on Nuclear Physics [PDF]
Acta Physica Polonica B, 2013 Presented at the Zakopane School on Nuclear Physics "Extremes of the Nuclear Landscape", August 27 - September 2, 2012, Zakopane ...
openaire +3 more sources