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The Regulation of Trace Metal Elements in Cancer Ferroptosis
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang+5 more
wiley +1 more source
AISI 304L stainless steel powder is mixed with silicon nitride (Si3N4) powder and processed by PBF‐LB/M, allowing partial retention of Si3N4. The numerical approach effectively predicts the Si3N4 powder homogeneity and N content distribution on the powder bed. Recent studies have focused on the alloying of nitrogen (N) in high‐alloy stainless steels by
Yuanbin Deng+7 more
wiley +1 more source
CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly
Mathiowetz AJ+20 more
europepmc +1 more source
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur+5 more
wiley +1 more source
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez+5 more
wiley +1 more source
Additive manufacturing of magnesium alloys by laser is difficult because the melting point of the oxide layer is much higher than the evaporation temperature of the metal underneath. Making the oxide layer thinner can solve this problem. Alloying magnesium with strontium makes the oxide layer thinner, especially at 0.5 wt%.
Elmar Jonas Breitbach+8 more
wiley +1 more source
Incorporating nanosized silver into titanium for antimicrobial materials exploits the metastable miscibility gap between silver and titanium. Silver nanoparticles are synthesized via pulsed laser ablation in liquid. Silver addition refines the microstructure, increases hardness by 30%, and reduces Staphylococcus capitis microbial adhesion by 70%, with ...
Hamed Shokri+4 more
wiley +1 more source
The nuclear pore complex [PDF]
The nuclear pore complex is the largest supramolecular complex that assembles in the eukaryotic cell. This structure is highly dynamic and must disassemble prior to mitosis and reassemble after the event. The directed movement of macromolecules into and out of the nucleus occurs through the nuclear pore complex, a potentially regulatory point for ...
Natasha V. Raikhel, Antje Heese-Peck
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Journal of Cell Science, 2000
All transport between the nucleus and the cytoplasm passes through the nuclear pore complex (NPC) (Functions). Small (20–40 kDa) molecules passively diffuse through the NPC, whereas there are a series of signal- and temperature-dependent mechanisms for large molecules.
Martin W. Goldberg+4 more
openaire +3 more sources
All transport between the nucleus and the cytoplasm passes through the nuclear pore complex (NPC) (Functions). Small (20–40 kDa) molecules passively diffuse through the NPC, whereas there are a series of signal- and temperature-dependent mechanisms for large molecules.
Martin W. Goldberg+4 more
openaire +3 more sources
Autoantigens of the nuclear pore complex
Journal of Molecular Medicine, 2004The nuclear envelope (NE) is one of many intracellular targets of the autoimmune response in patients with autoimmune liver disease, systemic lupus erythematosus, and related conditions. In eukaryotic organisms the NE consists of five interconnected regions: an outer nuclear membrane (ONM) that is continuous with the endoplasmic reticulum, an ...
Young Ou+5 more
openaire +3 more sources