Results 91 to 100 of about 93,374 (191)

NXT2 is a key component of the RNA nuclear export factor complex in the human testis and essential for spermatogenesis

open access: yesNature Communications
In eukaryotes, the nucleocytoplasmic export of bulk poly(A)+-mRNAs through the nuclear pore complex is mediated by the ubiquitously expressed NXT1-NXF1 heterodimer.
Ann-Kristin Dicke   +14 more
doaj   +1 more source

Disrupted nuclear import of cell cycle proteins in Huntington's/PolyQ disease causes neurodevelopment defects in cellular and Drosophila model

open access: yesHeliyon
Huntington's disease is caused by an expansion of CAG repeats in exon 1 of the huntingtin gene encoding an extended PolyQ tract within the Huntingtin protein (mHtt).
Sandeep Kumar Dubey   +2 more
doaj   +1 more source

Fluorescence Anisotropy Reveals Order and Disorder of Protein Domains in the Nuclear Pore Complex [PDF]

open access: bronze, 2010
Alexa L. Mattheyses   +3 more
openalex   +1 more source

Reconstitution of nuclear envelope subdomain formation on mitotic chromosomes in semi-intact cells

open access: yesCell Structure and Function
In metazoans, the nuclear envelope (NE) disassembles during the prophase and reassembles around segregated chromatids during the telophase. The process of NE formation has been extensively studied using live-cell imaging.
Tomoko Funakoshi, Naoko Imamoto
doaj   +1 more source

Nuclear pore protein NUP88 activates anaphase-promoting complex to promote aneuploidy [PDF]

open access: bronze, 2016
Ryan M. Naylor   +3 more
openalex   +1 more source

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