Results 41 to 50 of about 1,607,631 (347)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Analysis of the Brayton cycle coupled with a small fluoride salt-cooled high-temperature reactor

open access: yesFrontiers in Energy Research, 2023
Considering the environmental conditions and transportation conditions of remote areas, an inherently safe integrated energy conversion system featuring miniaturization, modularization, and high environmental adaptability is needed.
Xiuting Liu   +6 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Cost Escalation in Nuclear Power [PDF]

open access: yes, 1978
This report is concerned with the escalation of capital costs of nuclear central station power plants between the early 1960s and the present. The report presents an historical overview of the development of the nuclear power industry and cost escalation
Montgomery, W. David, Quirk, James P.
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Rescattering effects in hadron-nucleus and heavy-ion collisions

open access: yes, 2005
We review the extension of the factorization formalism of perturbative QCD to {\it coherent} soft rescattering associated with hard scattering in high energy nuclear collisions.
0207   +34 more
core   +1 more source

Fracture analysis of the planet support used in a nuclear power plant

open access: yesMATEC Web of Conferences, 2016
In this paper, the fracture analysis of the planet support, which was made of aluminium alloy and used in an electric actuator, was investigated. The laboratory analysis was conducted to find out whether there are defects generated during manufacturing ...
Zu Shuai   +5 more
doaj   +1 more source

Improvement of methods for controlling power oil of cooling tower recycling water supply units at Rivne nuclear power plant [PDF]

open access: diamond, 2022
Павло Кузнєцов   +3 more
openalex   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

The Impact of China’s Investment in Nuclear Energy on the Reputation of Nuclear Power and the World’s Energy Supply [PDF]

open access: yes, 2014
Over the past ten years, China’s involvement in nuclear power has increased dramatically. The country has seemingly unlimited resources to build nuclear power centers and has no qualms about using these resources.
Mattson, Laura
core   +1 more source

Home - About - Disclaimer - Privacy