Results 81 to 90 of about 372,244 (310)

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Prospects for Nuclear Power [PDF]

open access: yes
The prospects for a revival of nuclear power were dim even before the partial reactor meltdowns at the Fukushima nuclear plant. Nuclear power has long been controversial because of concerns about nuclear accidents, proliferation risk, and the storage of ...
Lucas W. Davis
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Universal computer vision system for monitoring the main parameters of wind turbines

open access: yesE3S Web of Conferences, 2016
The article presents universal autonomous system of computer vision to monitor the operation of wind turbines. The proposed system allows to estimate the rotational speed and the relative position deviation of the wind turbine.
Korzhavin Sergey   +4 more
doaj   +1 more source

The cost of phasing out nuclear power: a quantitative assessment of alternative scenarios for Germany [PDF]

open access: yes
In the debate on the premature phase-out of nuclear power generation in Germany, there is an intense dispute on the effective operating time for the existing nuclear power plants. This paper addresses the question of how alternative phase-out regulations
Böhringer, Christoph   +2 more
core  

The future of nuclear power in the United States : economic and regulatory challenges [PDF]

open access: yes, 2006
This paper examines the economic and regulatory challenges that must be faced by potential investors in new nuclear power plants in the United States.
Paul L. Joskow, Paul L. Joskow
core   +2 more sources

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Nuclear power: What optimal contribution to the French electric power mix? [PDF]

open access: yes, 2015
International audiencen the French context of increasing renewable penetration and significant nuclear power, the optimal contribution of this energy source is discussed from two viewpoints. On the one hand, from the social planner viewpoint, the nuclear
Cany, Camille   +3 more
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

17. Issues for Nuclear Power Plants Steam Generators [PDF]

open access: yes, 2011
Open Access ...
Bonavigo L., De Salve M.
core  

Home - About - Disclaimer - Privacy