Results 251 to 260 of about 8,215,941 (358)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Ultra-rapid detection of nuclear protein of severe fever with thrombocytopenia syndrome virus by colloidal gold immunochromatography assay. [PDF]

PeerJ
Huang Z, Li J, Wei W, Li H, Yan H, Chen R, Li J, Tie X, Wang D, Wu G, Zhang L, Zhang Y, Chen K, Lou Y.   +13 more
europepmc   +1 more source

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1.

Proceedings of the National Academy of Sciences of the United States of America, 1999
W. Biggs, J. Meisenhelder, T. Hunter, W. Cavenee, K. Arden   +4 more
semanticscholar   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Metabolic and Epigenetic Reprogramming in a Case of Nuclear Protein in Testis (NUT) Carcinoma of the Retroperitoneum. [PDF]

Cureus
Serizawa M, Serizawa K, Masui K, Toguchi M, Murakami K, Yamamoto T, Nagashima Y, Takagi T, Kurata A.   +8 more
europepmc   +1 more source

Identification of different roles for RanGDP and RanGTP in nuclear protein import.

EMBO Journal, 1996
Dirk, Gorlichl, Nelly Panté, Ulrike Kutay, Ueli Aebi, F. Bischoff   +5 more
semanticscholar   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Upregulation of nuclear protein Hemgn by transcriptional repressor Gfi1 through repressing PU.1 contributes to the anti-apoptotic activity of Gfi1. [PDF]

J Biol Chem
G C B, Hoyt LJ, Dovat S, Dong F.
europepmc   +1 more source

Protein O-GlcNAcylation: emerging mechanisms and functions

Nature reviews. Molecular cell biology, 2017
Xiaoyong Yang, Kevin Qian
semanticscholar   +1 more source

Figure S2 from A Targetable Secreted Neural Protein Drives Pancreatic Cancer Metastatic Colonization and HIF1α Nuclear Retention [PDF]

Norihiro Yamaguchi, Y. Gloria Wu, Ethan Ravetch, M Takahashi, Abdul G. Khan, Akimasa Hayashi, Wenbin Mei, Dennis Hsu, Shigeaki Umeda, Elisa de Stanchina, Ivo C. Lorenz, Christine A. Iacobuzio–Donahue, Sohail F. Tavazoie   +12 more
openalex   +1 more source