Results 191 to 200 of about 5,069,870 (397)

Direct and widespread role for the nuclear receptor EcR in mediating the response to ecdysone in Drosophila [PDF]

, 2019
Christopher M. Uyehara, Daniel J. McKay
openalex   +1 more source

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

Proceedings of the National Academy of Sciences of the United States of America, 2001
Jeff L. Staudinger, B. Goodwin, Stacey A. Jones, D. Hawkins-Brown, K. I. MacKenzie, A. Latour, Yaping Liu, C. Klaassen, K. Brown, J. Reinhard, T. Willson, B. Koller, S. Kliewer   +12 more
semanticscholar   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Nuclear Receptors [PDF]

Cell, 2003
Belandia, Borja, Parker, Malcolm G.
openaire   +1 more source

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR.

Molecules and Cells, 1999
Haibo Wang, Jasmine Chen, Kevin Hollister, L. Sowers, B. M. Forman   +4 more
semanticscholar   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals

Cell, 1997
M. Fornerod, M. Ohno, Minoru Yoshida, I. Mattaj   +3 more
semanticscholar   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

The orphan nuclear receptor NR4A3 is dispensable for resident memory CD8+ T-cell generation. [PDF]

Immunohorizons
Odagiu L, Boulet S, De Sousa DM, Daudelin JF, Labrecque N.   +4 more
europepmc   +1 more source

The Glutathione Transferase Structural Family Includes a Nuclear Chloride Channel and a Ryanodine Receptor Calcium Release Channel Modulator [PDF]

, 2001
Angela F. Dulhunty, Peter W. Gage, Suzanne M. Curtis, Gareth Chelvanayagam, Philip G. Board   +4 more
openalex   +1 more source