Results 271 to 280 of about 734,603 (316)

Progressive reduction of nuclear receptor Nr4a1 mediates age-dependent cognitive decline. [PDF]

Alzheimers Dement
Chen J, Zhang Z, Liu Y, Huang L, Liu Y, Yang D, Bao X, Liu P, Ge Y, Li Q, Shu X, Xu L, Shi YS, Zhu X, Xu Y.   +14 more
europepmc   +1 more source

Magnetic resonance imaging evaluation and nuclear receptor binding SET domain protein 1 mutation in the Sotos syndrome with attention-deficit/hyperactivity disorder.

World J Clin Cases
Zhu W.
europepmc   +1 more source

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Bioinformatics of Nuclear Receptors

2003
Publisher Summary This chapter reviews the information that biologists interested in nuclear receptors can get by using a computer, including general resources and those specialized in nuclear receptors, whether for accessing data or analyzing it.
Marc Robinson-Rechavi, Vincent Laudet
openaire   +6 more sources

Nuclear receptor coactivators

Current Opinion in Cell Biology, 1997
Retinoic acid, steroid and thyroid hormones regulate complex programs of gene expression by binding to intracellular receptors that are members of the nuclear receptor superfamily of ligand-dependent transcription factors. Recent studies have led to the identification and cloning of genes encoding coactivator molecules that appear to play important ...
Michael G. Rosenfeld, David W. Rose, Christopher K. Glass   +2 more
openaire   +2 more sources

Oxysterols and nuclear receptors

Molecular and Cellular Endocrinology, 2019
Oxysterols are derivatives of cholesterol and an important regulator of cholesterol metabolism, in part due to their role as ligands for nuclear receptors, such as the liver X receptors. Oxysterols are also known to be ligands for the RAR-related orphan receptors, involved in normal T cell differentiation.
Liqian Ma, Erik R. Nelson
openaire   +3 more sources

Ubiquitination of nuclear receptors

Clinical Science, 2017
Nuclear receptors (NRs) are cellular proteins, which upon ligand activation, act to exert regulatory control over transcription and subsequent expression. Organized via systemic classification into seven subfamilies, NRs partake in modulating a vast expanse of physiological functions essential for maintenance of life.
Jean Pierre Obeid, Zafar Nawaz, Celeste Amadei, Jimmy El Hokayem   +3 more
openaire   +3 more sources

Nuclear receptors and disease: androgen receptor [PDF]

Essays in Biochemistry, 2004
The androgen receptor (AR) protein regulates transcription of certain genes. Usually this depends upon a central DNA-binding domain that permits the binding of androgen–AR complexes to regulatory DNA sequences near or in a target gene. The AR also has a C-terminal ligand-binding domain and an Nterminal transcription modulatory domain.
Jianhui Wu, Mark Trifiro, Mark Trifiro, Lenore K. Beitel, Lenore K. Beitel, Youssef A. Elhaji, Youssef A. Elhaji, Bruce Gottlieb, Bruce Gottlieb   +8 more
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Insect Nuclear Receptors

Annual Review of Entomology, 2012
The nuclear receptors (NRs) of metazoans are an ancient family of transcription factors defined by conserved DNA- and ligand-binding domains (DBDs and LBDs, respectively). The Drosophila melanogaster genome project revealed 18 canonical NRs (with DBDs and LBDs both present) and 3 receptors with the DBD only.
Rodrigo A. Velarde, Guy Smagghe, Susan E. Fahrbach   +2 more
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