Results 111 to 120 of about 146,303 (307)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Nuclear Safeguards Education for European Nuclear Engineering Students

open access: yes, 2006
The knowledge retention problem in the nuclear field was acknowledged by the Organization for Economic Co-operation and Development (OECD) in 2000. ESARDA, the European Safeguards Research and Development Association (http://www.jrc.cec.eu.int/esarda ...
JANSSENS-MAENHOUT Greet   +2 more
core  

Nuclear Physics Laboratory 1976 annual report. [Nuclear Physics Laboratory, Univ. of Washington]

open access: yes, 1976
Laboratory activities for the period spring, 1975 to spring, 1976 are described. The emphasis of the work can be discerned from the chapter headings: accelerator development; ion source development; instrumentation, detectors, research techniques ...

core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

CORTEX experiments, Part III: Experimental determination of the zero power transfer function of AKR-2 with reliable uncertainties

open access: yes
The transfer function is an important characteristic quantity of a nuclear reactor, since it contains the kinetic parameters. It expresses the response of a nuclear reactor to a disturbance of a certain frequency.
Knospe, Alexander   +5 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Boiling heat transfer characteristics of steam generator U-tube fouling [PDF]

open access: yes, 1997
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Nuclear Engineering, 1997.Includes bibliographical references (leaves 109-111).The boiling heat transfer characteristics of steam generator u-tube fouling deposits were identified by ...
Uhle, Jennifer Lee
core  

New techniques in fourier transform nuclear magnetic resonance

open access: yes, 1982
New techniques in Fourier transform nuclear magnetic resonance spectroscopy are introduced with chemical applications to the study of molecules in the liquid state.Recently a theoretical description of magnetic resonance in terms of single transition ...
Mareci, Thomas Harold., Mareci, Thomas
core   +1 more source

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