Results 101 to 110 of about 339,303 (197)

A Pan-Cancer Analysis of the Oncogenic Role of Nuclear Transport Factor 2 in Human Cancers. [PDF]

Front Oncol, 2022
Li Y, Huang Y, Ren S, Xiao X, Cao H, He J.   +5 more
europepmc   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Advances and transgressions of nuclear transport checkpoint inhibitors. [PDF]

Mol Ther
Hawiger J.
europepmc   +1 more source

Nuclear transport genes recurrently duplicate by means of RNA intermediates in Drosophila but not in other insects. [PDF]

BMC Genomics, 2021
Mirsalehi A, Markova DN, Eslamieh M, Betrán E.   +3 more
europepmc   +1 more source

From 2D to 3D gamma passing rate tolerance and action limits for patient‐specific quality assurance in volumetric‐modulated arc therapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Volumetric modulated arc therapy (VMAT) requires an accurate patient‐specific quality assurance (PSQA) program. In clinical practice, this is usually performed using the γ‐index and the two‐dimensional gamma passing rate (2D %GP). A three‐dimensional (3D) index incorporating the patient anatomy could be more useful for the 3D dose ...
Christos Zarros, George Patatoukas, Nikos Kollaros, Marina Chalkia, Andromachi Kougioumtzopoulou, Vasilios Kouloulias, Kalliopi Platoni   +6 more
wiley   +1 more source

Gene alterations in the nuclear transport receptor superfamily: A study of head and neck cancer. [PDF]

PLoS One
Nguyen PT, Shimojukkoku Y, Kajiya Y, Oku Y, Tomishima A, Shima K, Sasahira T.   +6 more
europepmc   +1 more source

Inhibitor of the Nuclear Transport Protein XPO1 Enhances the Anticancer Efficacy of KRAS G12C Inhibitors in Preclinical Models of KRAS G12C-Mutant Cancers. [PDF]

Cancer Res Commun, 2022
Khan HY, Nagasaka M, Li Y, Aboukameel A, Uddin MH, Sexton R, Bannoura S, Mzannar Y, Al-Hallak MN, Kim S, Beydoun R, Landesman Y, Mamdani H, Uprety D, Philip PA, Mohammad RM, Shields AF, Azmi AS.   +17 more
europepmc   +1 more source

Impact of enhanced leaf model on dose calculation accuracy in single‐isocenter multitarget stereotactic radiosurgery treatments

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Single‐isocenter multitarget (SIMT) radiosurgery has become increasingly popular as advancement in planning and delivery systems have made this approach clinically viable. With targets varying in size and distance from isocenter, SIMT plans are highly complex with dynamic multileaf collimator (MLC) motion.
Hem Moktan, Hongyu Jiang, H. Harold Li, Kenny Guida   +3 more
wiley   +1 more source

Anti-inflammatory control of human skin keratinocytes by targeting nuclear transport checkpoint. [PDF]

Skin Health Dis
Liu Y, Qiao H, Zienkiewicz J, Hawiger J.
europepmc   +1 more source

Dose rate correction of a diode array for universal wedge field dosimetric verification

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To study the performance of MapCHECK 3 (MC3) in measuring universal wedge fields and propose a dose rate correction strategy to improve MC3 measurement accuracy. Materials and methods Universal wedge fields with different wedge angles and field sizes were measured at different depths using MC3.
Linyi Shen, Mengyang Li, Guiyuan Li, Xinyuan Chen, Shouping Xu, Jianrong Dai, Yuan Tian   +6 more
wiley   +1 more source