Results 51 to 60 of about 470,414 (263)
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Potential Implications of the Russia–Ukraine War for Northeast Asia
Journal for Peace and Nuclear Disarmament, 2023 The Russia–Ukraine war has caused decision-makers worldwide to acknowledge the thinkability (plausibility) of limited nuclear war. It has probably reduced any confidence China may have about being able easily and quickly to invade Taiwan.
Paul K. Davis
doaj +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Mission Unaccounted: Japan’s Shift of Role in US Extended Nuclear Deterrence
Journal for Peace and Nuclear Disarmament, 2022 Japan’s security policy appears to be undergoing a qualitative change. Policymakers, however, have not provided sufficient explanation to the nation regarding such a shift. What is the qualitative change in Japan’s security policy premised on US extended
Kimiaki Kawai
doaj +1 more source
Kantian Nonideal Theory and Nuclear Proliferation [PDF]
, 2010 Recent revelations of Iran’s hitherto undisclosed uranium enrichment programs have once again incited western fears that Tehran seeks nuclear weapons’ capability. Their fears seem motivated by more than the concern for compliance
Doyle, Ii, Thomas E.
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Global Zero: The new old agenda [PDF]
, 2009 The project of abolishing all nuclear weapons has been given fresh impetus but the old questions remain. Having regard to the manifold problems of definition and verification, is 'Global Zero' realistic in a world in which proliferation seems more likely
Smith, Ron C.
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Images of survival, stories of destruction: Nuclear war on British screens from 1945 to the early 1960s [PDF]
, 2013 This article discusses a range of depictions and discussions of nuclear war, which appeared on British screens in the first half of the Cold War, in order to understand the changing way nuclear weapons were viewed within British culture.
Boyer Paul S. +10 more
core +1 more source