Results 71 to 80 of about 466,448 (222)

DEVOTED ACTOR VERSUS RATIONAL ACTOR MODELS FOR UNDERSTANDING WORLD CONFLICT Presented To The National Security Council At The White House, September 14, 2006 [PDF]

open access: yes
Ever since the end of the Second World War, Rational Actor models have dominated strategic thinking at all levels of government policy and military planning.
Scott Atran
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Creating a Canadian profession: the nuclear engineer, c. 1940-1968 [PDF]

open access: yes, 2009
Canada, as one of the three Allied nations collaborating on atomic energy development during the Second World War, had an early start in applying its new knowledge and defining a new profession. Owing to postwar secrecy and distinct national aims for the
Johnston, S.F.
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Nuclear astrophysicists at war

open access: yesNatural Sciences
The question of energy production in stars stimulated an entire generation of young physicists in the 1930s who came to work in this field exploring the fundamentals of quantum and nuclear physics. Their experience and methodologies were essential to the
Michael Wiescher, Karlheinz Langanke
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Pathways towards the nuclear revival in Finland, France, and the UK [PDF]

open access: yes, 2010
Nuclear power is undergoing a revival in a number of countries of both developed and developing world, and is increasingly presented as a solution to the problems of climate change and energy security.
Lehtonen, Markku, Martiskainen, Mari
core  

The Code of Protest. Images of Peace in the West German Peace Movements, 1945-1990 [PDF]

open access: yes, 2008
The article examines posters produced by the peace movements in the Federal Republic of Germany during the ColdWar, with an analytical focus on the transformation of the iconography of peace in modernity.
Andreas   +76 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Nuclear Threat and the Image of the American Enemy in Soviet Cold War Posters [PDF]

open access: yesТелекинет
The emergence and evolution of nuclear weapons contributed to the rise of one of the main narratives of the Cold War in both the political and socio-cultural fields.
Prosolova, E.V
doaj   +1 more source

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