Results 161 to 170 of about 438,619 (385)

Basic polypeptides as histone models. Effect of conformation, base composition and methylation of nucleic acids on the interaction with Hl and histone models and on the circular dichroism of complexes.

, 1976
J. Šponar, J. Doskočil, K. Bláha, Ch. Zimmer   +3 more
openalex   +2 more sources

Conformational constraints of cyclopentane peptide nucleic acids facilitate tunable binding to DNA [PDF]

, 2020
Hongchao Zheng, Istvan Botos, Victor Clausse, Herman Nikolayevskiy, Elizabeth E. Rastede, Munira F. Fouz, Sharlyn J. Mazur, Daniel H. Appella   +7 more
openalex   +1 more source

Designing the Self‐Assembly of Disordered Materials Via Color Frustration

Advanced Materials, EarlyView.
What if disorder can be designed? This work introduces a strategy to self‐assemble amorphous materials by designing bonding rules for patchy particles that suppress crystallinity and promote frustration. The designer particles nucleate a network of dodecahedral cages from the liquid, yielding a novel equilibrium amorphous phase. This approach redefines
Andreas Neophytou, Francesco Sciortino, John Russo   +2 more
wiley   +1 more source

Nucleic Acid Reactivity and Conformation

, 1973
Robert Shapiro, Barbara Braverman, Judith B. Louis, Robert E. Servis   +3 more
openalex   +1 more source

Impact of modified ribose sugars on nucleic acid conformation and function

, 2017
Marina G Evich, Alexander M. Spring-Connell, M. Germann   +2 more
semanticscholar   +1 more source

Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas

Advanced Materials, EarlyView.
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac, Luv Patel, Nguyen Tran, Amarnath Singam, DongSoo Yun, Prasun Guha, Seungman Park, Chandrabali Bhattacharya   +7 more
wiley   +1 more source

Use of the Z-DNA binding domain of ADAR1 as a probe for nucleic acids in left-handed conformation [PDF]

, 2008
Heng Li
openalex   +1 more source

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

Advanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania, Manus J. P. Biggs, Katarzyna Krukiewicz   +2 more
wiley   +1 more source

Natural-occurring Z-conformations in nucleic acids: probed by the Z?� domain of human RNA editing enzyme [PDF]

, 2010
Feng Shu
openalex   +1 more source

Investigating the Mechanism of Ion Concentration Polarization Within Nanofluidic Hydrogel Membranes: Experiment and Simulation

Advanced Materials Interfaces, EarlyView.
Molecular dynamics simulations are employed to model ion concentration polarization (ICP) at the nanoscale, revealing fundamental electrokinetic behaviors that align with experimental observations. The study demonstrates how membrane charge, ionic strength, and electric fields affect ion localization and biomolecule trapping, providing mechanistic ...
Hiba Aljayyousi, Jongmin Kim, Serdal Kirmizialtin, Yong‐Ak Song   +3 more
wiley   +1 more source