Results 191 to 200 of about 369,422 (270)

Unknotting RNA: A method to resolve computational artifacts. [PDF]

open access: yesPLoS Comput Biol
Poblete S, Mlynarczyk M, Szachniuk M.
europepmc   +1 more source

Coacervates as enzymatic microreactors.

open access: yesChem Soc Rev
Harris R, Berman N, Lampel A.
europepmc   +1 more source

PROTON MAGNETIC RESONANCE STUDIES OF NUCLEIC ACID CONFORMATION *

Annals of the New York Academy of Sciences, 1973
Much of the previous effort of our laboratory in the area of proton magnetic resonance studies has been devoted to the development of a conformational model for the dinucleoside monophosphates.*-" More recently, the influence of the 2'-hydroxyl group on ...
P. Ts'o, J. Barrett, L. Kan, P. Miller
semanticscholar   +4 more sources

Theoretical Probes of Nucleic Acid Conformation

, 1983
The computations described briefly here illustrate the interrelationship between the local structure and macroscopic behavior of the DNA helix. Statistical mechanical studies help to identify the most likely morphological arrangements of the polynucleotide backbone and to understand the macroscopic flexibility of the DNA as a whole.
W. Olson
semanticscholar   +3 more sources

Nucleic acid analogs: Conformation and their functionalities

Die Makromolekulare Chemie, 1985
Poly-L-, -D-, and -DL-lysine derivatives having pendant nucleic acid bases were prepared by using a polymer modification reaction. Conformation of the polymers was studied by CD and ORD measurements, and the effects of pH of the system, as well as the ...
K. Takemoto
semanticscholar   +3 more sources

Calculations of nucleic acid conformations

Current Opinion in Structural Biology, 1996
The present computational power and sophistication of theoretical approaches to nucleic acid structural investigation are sufficient for the realization of static and dynamic models that correlate accurately with current crystallographic, NMR and solution-probing structural data, and consequently are able to provide valuable insights and predictions ...
Auffinger, Pascal   +2 more
openaire   +4 more sources

The conformations of locked nucleic acids (LNA)

Journal of Molecular Recognition, 2000
We have used 2D NMR spectroscopy to study the sugar conformations of oligonucleotides containing a conformationally restricted nucleotide (LNA) with a 2'-O, 4'-C-methylene bridge. We have investigated a modified 9-mer single stranded oligonucleotide as well as three 9- and 10-mer modified oligonucleotides hybridized to unmodified DNA.
Petersen, Michael B.   +10 more
openaire   +4 more sources

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