Results 241 to 250 of about 2,997,790 (301)

Caveat emptor: predicting and modeling protein-DNA recognition and binding via machine-learning computational approaches. [PDF]

Nucleic Acids Res
Esler MA, Werther R, Doyle LA, Ubilla-Rodriguez NC, Schwensen JS, Hallinan JP, Lambert AR, Young JC, Silverstein M, Stoddard BL.   +9 more
europepmc   +1 more source

Molecular basis of tRNA substrate recognition and modification by the atypical SPOUT methyltransferase Trm10. [PDF]

Nucleic Acids Res
Nandi S, Strassler SE, Dey D, Whitney CB, Roumaya OB, Krishnamohan A, Harris GM, Comstock LR, Jackman JE, Conn GL.   +9 more
europepmc   +1 more source

Human cathelicidin peptide LL-37 compacts nucleic acids and alters neutrophil extracellular trap structure. [PDF]

Sci Rep
Zielke C, Rad B, Nielsen JE, Li J, Pimcharoen S, Sawant M, Kamayirese S, Lin JS, Thiam HR, Barron AE.   +9 more
europepmc   +1 more source

Architecture of a DNA-guided Cas12a. [PDF]

Nat Struct Mol Biol
Ocampo RF, Orosco C, Huang B, West MS, Parker B, Jain PK, Taylor DW.   +6 more
europepmc   +1 more source

PockFlex: a web server for flexibility-aware binding site identification and prioritisation from structural ensembles. [PDF]

Nucleic Acids Res
Rahali IS, Serir Y, Rahali K, Flatters D, Regad L, Camproux AC.   +5 more
europepmc   +1 more source

The Z-nucleic acid sensor ZBP1 in health and disease

Journal of Experimental Medicine, 2023
ZBP1 is an innate immune sensor for double-stranded nucleic acids adopting the Z conformation. Z-RNA/DNA is generated during viral infections and in autoinflammation and cancer.
Jonathan Maelfait, Jan Rehwinkel
exaly   +2 more sources

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Calculations of nucleic acid conformations

Current Opinion in Structural Biology, 1996
The present computational power and sophistication of theoretical approaches to nucleic acid structural investigation are sufficient for the realization of static and dynamic models that correlate accurately with current crystallographic, NMR and solution-probing structural data, and consequently are able to provide valuable insights and predictions ...
Auffinger, Pascal, Louise-May, Shirley, Westhof, Eric   +2 more
openaire   +4 more sources

The conformations of locked nucleic acids (LNA)

Journal of Molecular Recognition, 2000
We have used 2D NMR spectroscopy to study the sugar conformations of oligonucleotides containing a conformationally restricted nucleotide (LNA) with a 2'-O, 4'-C-methylene bridge. We have investigated a modified 9-mer single stranded oligonucleotide as well as three 9- and 10-mer modified oligonucleotides hybridized to unmodified DNA.
Jesper Wengel, Michael Petersen, Jens Peter Jacobsen   +2 more
exaly   +4 more sources