Results 91 to 100 of about 67,253 (293)
, 1969 Spectra of toluidine blue with acid mucopolysaccharides and nucleic acids were recorded over the temperature range 10-70°C. Metachromatic ratios were inverse, linear functions of temperature. Intercepts and slopes of the thermal plots distinguished acid
FRED ROTHSTEIN +2 more
core +1 more source
Feasibility of microfluidic routes to monitor protein stability as a tool for bioprocessing
, 2010 During the bioprocessing of therapeutics, proteins may become damaged leading to modifications and changes in stability. This may, as a consequence, cause serious and potentially fatal side effects when administered to patients making damage ...
Remtulla, N.
core
Soni-removal of nucleic acids from inclusion bodies
, 2014 Inclusion bodies (IBs) are commonly formed in Escherichia coli due to over expression of recombinant proteins in non-native state. Isolation, denaturation and refolding of these IBs is generally performed to obtain functional protein.
Neerathilingam, Muniasamy +2 more
core +1 more source
Fine structure of nucleic acid hairpins and duplexes
, 1994 Studies of the relationship between nucleic acid structure and function are limited by the rudimentary understanding of the forces that drive structure formation. New methods for identifying the structure and stability of nucleic acid fragments have been
Testa, Stephen Michael
core
, 2016 Hybridization of complementary nucleic acid strands is fundamental to nearly all molecular bioanalytical methods ranging from polymerase chain reaction and DNA biosensors to next generation sequencing.
Andrew R. Mount (1718773) +5 more
core +1 more source
Chemistry – A European Journal, EarlyView.5‐Substituted 2‐(naphthalen‐2‐yl)‐4H‐chromen‐4‐ones are reported as a novel class of highly potent and selective triplex DNA ligands. These ligands induce triplex formation at submicromolar concentrations and inhibit enzymatic activity via ligand‐mediated triplex formation.
Nghia Tran +4 more
wiley +1 more source
The Canadian Journal of Chemical Engineering, EarlyView.Schematic representation of artificial intelligence approaches in enzyme catalysis, integrating bibliometric analysis, emerging research trends, and machine learning tools for enzyme design, prediction, and industrial biocatalytic applications. Abstract This study systematically explores the applications of artificial intelligence (AI) in enzyme ...
Misael Bessa Sales +6 more
wiley +1 more source
High throughput oscillating-flow structure for polymerase chain reaction
AIP AdvancesPolymerase chain reaction (PCR) is a revolutionary biomolecule technology that drives the development of bioscience. The current work reports a high throughput oscillating-flow PCR structure.
Ranran Zhou +7 more
doaj +1 more source
Food Chemistry International, EarlyView.This review highlights non‐thermal extraction technologies for seaweed proteins, emphasizing their mechanisms, impacts on protein structure and functionality, and sustainability potential. Key limitations related to species dependence, extract complexity, and scale‐up are discussed to guide future industrial and biorefinery applications.
Rahat Mahmud +3 more
wiley +1 more source
Food Chemistry International, EarlyView.Pulsed light technology uses short high‐intensity broad‐spectrum flashes (200–1100 nm) to inactivate microbes via DNA damage. It preserves food quality, extends shelf life, and works on liquids, meats, and produce, often combined with other hurdles for enhanced efficacy.
Abdul Mueez Ahmad +4 more
wiley +1 more source