Results 71 to 80 of about 146,288 (301)
Computer programs to assist in high resolution thermal denaturation and circular dichroism studies on nucleic acids [PDF]
Nucleic Acids Research, 1981 Computer programs are described that direct the collection, processing, and graphical display of numerical data obtained from high resolution thermal denaturation (1-3) and circular dichroism (4) studies. Besides these specific applications, the programs may also be useful, either directly or as programming models, in other types of spectrophotometric ...T C, Goodman, S C, Hardies, C, Cortez, W, Hillen +3 moreopenaire +2 more sourcesGenetic Control of Tissue Remodeling by a Non‐Coding SNP in ITGA8 Explains Carotenoid‐Based Color Polymorphism in Marine Mollusks
Advanced Science, EarlyView.In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...Xiaohui Wei, Wenzhu Peng, Zekun Huang, Bingye Yang, Yiyu Wu, Minzhen Han, Yi Wang, Bingling Peng, Guosheng Hu, Jiawei Hong, Guijia Liu, Linwei Nie, Yang Gan, Miaoqin Huang, Xuan Luo, Weiwei You, Wen Liu, Caihuan Ke +17 morewiley +1 more sourceGlutamine Deprivation Triggers Tribbles Homolog 3 Dependent G‐Quadruplex Resolution to Maintain DNA Repair and Tumor Survival
Advanced Science, EarlyView.Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes Qiang Ji, Xuedan Sun, Zhangran Sun, Mengfan Li, Xinyu Cheng, Shuai Tian, Rick F. Thorne, Jinming Li, Guangzhi Liu, Mian Wu, Xiaoying Liu +10 morewiley +1 more sourceSertoli Cell‐Derived Extracellular Vesicles Orchestrate Cadmium‐Induced Testicular Inflammation and Fibrosis
Advanced Science, EarlyView.Environmental cadmium exposure disrupts testicular homeostasis through a novel intercellular communication axis. Stressed Sertoli cells release extracellular vesicles carrying damage‐associated molecular patterns and mitochondrial fragments, which activate macrophages via TLR4/NF‐κB signaling.Jianfeng Ma, Mailin Gan, Shuang Liang, Siyu Chen, Ziling Hao, Yiting Yang, Jiawei Lu, Qihang Wu, Yuqian Shi, Lijun Sun, Jiaxin Li, Saihao Wang, Yan Wang, Xiaofeng Zhou, Lei Chen, Ye Zhao, Li Zhu, Linyuan Shen +17 morewiley +1 more sourceFunctionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking
Nature CommunicationsSingle-particle cryo-EM is widely used to determine enzyme-nucleosome complex structures. However, cryo-EM sample preparation remains challenging and inconsistent due to complex denaturation at the air-water interface (AWI).Un Seng Chio, Eugene Palovcak, Anton A. A. Smith, Henriette Autzen, Elise N. Muñoz, Zanlin Yu, Feng Wang, David A. Agard, Jean-Paul Armache, Geeta J. Narlikar, Yifan Cheng +10 moredoaj +1 more sourceMechanochemistry of nucleosides, nucleotides and related materials
Beilstein Journal of Organic Chemistry, 2018 The application of mechanical force to induce the formation and cleavage of covalent bonds is a rapidly developing field within organic chemistry which has particular value in reducing or eliminating solvent usage, enhancing reaction rates and also in ...Olga Eguaogie, Joseph S. Vyle, Patrick F. Conlon, Manuela A. Gîlea, Yipei Liang +4 moredoaj +1 more sourceSingle-molecule experiments in biological physics: methods and
applications
, 2006 I review single-molecule experiments (SME) in biological physics. Recent
technological developments have provided the tools to design and build
scientific instruments of high enough sensitivity and precision to manipulate
and visualize individual ..., , , , , Adachi K, Adelman K, Ahsan A, Alberts B, Allahverdyan A, Allemand J F, Altan-Bonnet G, Ashkin A, Ashkin A, Ashkin A, Ashkin A, Ashkin A, Ashkin A, Astumian R D, Astumian R D, Baumann C G, Baumann C G, Bell G I, Bennett C H, Bennink M L, Bennink M L, Bensimon D, Best R B, Bhasin N, Bhattacharjee S M, Bhattacharjee S M, Binnig G, Binnig G, Blanchard S C, Blickle V, Block S M, Block S M, Bloomfield V A, Bochkov G N, Bockelmann U, Boroudjerdi H, Bouchiat C, Braslavsky I, Brower-Toland B D, Brujic J, Bryant Z, Bundschuh R, Burgess S A, Bustamante C, Bustamante C, Bustamante C, Bustamante C, Calladine C R, Carl P, Carrion-Vazquez M, Carrion-Vazquez M, Carrion-Vazquez M, Carter N J, Carter N J, Causo M S, Charvin G, Chatenay D, Chen S-J, Ciliberto S, Clausen-Schaumann H, Cluzel P, Cocco S, Cocco S, Cocco S, Cocco S, Cocco S, Cohen E G D, Cohen E G D, Cohen E G D, Crooks G E, Crooks G E, Cross R A, Cuesta-Lopez S, Cui Y, Cui Y, Cule D, Czajkowsky D M, Córdova N J, Daban J R, Dammer U, Dammer U, Danilowicz C, Davenport R J, De Duve C, Dekker N H, Deng H, Discher D E, Dohoney K M, Douarche F, Eisenberg E, Engel A, Essevaz-Roulet B, Evans D J, Evans E, Evans E, Evans E, Evans E, Evans E, F Ritort, Fain B, Fernandez J M, Fernandez J M, Fernandez J M, Finer J T, Finkelstein A V, Finzi L, Fisher M E, Florin E L, Flyvbjerg H, Forde N R, Forkey J N, Frank-Kamentskii M D, Frechet J M, Fritz J, Fréchet J M J, Gallavotti G, Garces-Chavez V, Garcia-Manyes S, Gelles J, Gelles J, Gelles J, Gergely C, Gerland U, Gerland U, Gerland U, Gestland R F, Goel A, Goel A, Gordon M P, Gore J, Gore J, Gosse C, Grange W, Green N H, Grier D G, Gross D H E, Ha T, Ha T, Hafner J H, Hanggi P, Hanke A, Hanley W, Hansen J C, Haran G, Harlepp S, Herschlag D, Higgs P G, Hill T L, Hill T L, Hinterdorfer P, Howard J, Hummer G, Hummer G, Hwa T, Hyeon C, Inoue A, Isralewitz B, Jarzynski C, Jarzynski C, Jarzynski C, Jarzynski C, Jensen M O, Jeruzalmi D, Junier I Ritort F, Jülicher F, Kafri Y, Katritch V, Kawakami M, Keller D, Keller D, Kellermayer M S K, Kellermayer M S, Kim H D, Kindt J, Kitamura K, Klimov D K, Klug A, Konrad M W, Kosikov K M, Kosztin I, Kramers H A, Kukowska-Latallo J F, Kunze K-K, Kurchan J, Kühner F, Ladoux B, Lang M J, Lang M J, Law R, Lebowitz J L, Lebrun A, Lee G U, Lee G U, Leger J F, Leuba S H, Leuva S H, Lhua R C, Li P T X Bustamante C Tinoco I, Liphardt J, Liu F, Lu H, Léger J F, Maes C, Maes C, Maier B, Manosas M, Manosas M Wen J D Li P T X Smith S B Bustamante C Tinoco I Ritort F, Marko J, Marko J, Marko J F, Marszalek P E, Marszalek P E, Marszalek P E, Masaike T, Mathews D H, Mazonka O Jarzynski C, McGurn A R, Merkel R, Min W, Moffitt J R, Molloy J E, Moy V T, Muller D J, Munoz V, Müller D J, Müller M, Müller M, Nayashima M, Nelson D R, Nguyen T T Grossberg A Y Shklovskii B I Holm C Kekicheff P Podgornik R, Noji H, Noy A, Oberhauser A F, Onoa B, Onoa B, Onuchic J N, Oono Y, Orland H, Orlandini E, Orphanides G, Paci E, Pagnani A, Pan J, Pant K, Park S, Pauling L, Perret E, Peyrard M, Phillips W D, Poirier M G, Poland D, Poland D, Purohit P K, Qian H, Qu X, Rief M, Rief M, Rief M, Rief M, Rief M, Rief M, Ritort F, Ritort F, Ritort F, Ritort F, Ros R, Rouzina I, Rouzina I, Rubinstein M, Saleh O A, Sarkar A, Schiessel H, Schiessel H, Schlierf M, Schroeder R, Schumakovitch I, Schurr J M, Schwesinger F, Seifert U, Sellers J R, Shaevitz J W, Smith B L, Smith D E, Smith S B, Soong R K, Sosnick T R, Speck T, Spudich A, Strick T, Strick T R, Strick T R, Strick T R, Strunz T, Svoboda K, Tanaka H, Thirumalai D, Thurmond K B, Tinoco I, Tinoco I, Tinoco I, Tinoco I, Tinoco I, Treiber D K, Treiber D K, Trepagnier E H, Tsallis C, Uemura S, Uptain S M, Valpuesta J M, Vanzi F, Veigel C, Veigel C, Visscher K, Vologodskii A, Wang M D, Wang M D, Wartell R M, Watson J D, Watson J D, Wen J D Manosas M Li P T X Smith S B Bustamante C Ritort F Tinoco I, Wenner J R, Widom J, Wiita A P, Wilkins M H F, Williams M C, Williams M C, Williams M C, Williams P M, Williams P M, Wood R H, Woodcock C L, Wuite G J L, Xie Z, Yager T D, Yang G, Yasuda R, Yasuda R, Yildiz A, Yildiz A, Yin H, Zandi R, Zarrinkar P, Zhou H, Zhuang X, Zuckermann D M, Zuker M, Zwanzig R W +351 morecore +1 more source
