Results 141 to 150 of about 67,468 (297)

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Prevalence of Eight Viruses in Captive Amur Tigers (Panthera tigris altaica) From Harbin, China 中国哈尔滨市圈养东北虎8种病毒的流行

Wildlife Letters, EarlyView.
The Amur tiger, an endangered flagship species mainly found in the Russia Far East and Northeastern China, holds immense biological importance, and has been listed under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES).
Wei Xie, Luyao Wang, Mengna Chen, Qinjie Chang, Hongyu Jiang, Haitao Xu, Liu Dan, Xiang Li, Yulong Wang, Xiangwei Zeng, Bin Yang, Miaowei Wang, Yonggang Jiang, Hongliang Chai, Siyuan Yang, Yajun Wang   +15 more
wiley   +1 more source

Integrating Chemical, Electrical, and Photonic Effects Into a Unified ETOP‐Based Plasma Dose Framework

High Voltage, EarlyView.
ABSTRACT In plasma medicine and biological applications, plasmas typically deliver a complex combination of reactive chemical species and multiple physical energy components. However, establishing a unified and comparable dose metric to characterise their integrated biological effects remains a major challenge that continues to limit progress in this ...
Erqi Wu, Jialin Liu, Zhiyu Li, Dawei Liu, Lanlan Nie, Xinpei Lu   +5 more
wiley   +1 more source

Genetic differentiation and adaptive evolution of buff‐tailed bumblebees in Asia

Insect Science, EarlyView.
This study investigates the genetic differentiation and local adaptation of the buff‐tailed bumblebee (Bombus terrestris) across its European and Asian populations. Using whole‐genome resequencing, we identified distinct genetic differences between populations, with Asian B. terrestris representing a unique genetic resource.
Long Su, Lele Ding, Paul H. Williams, Yan Liu, Ruijuan Wang, Xiaoyan Dai, Shan Zhao, Haolin Fu, Xiaomeng Zhao, Quangui Wang, Yancan Li, Huiling Sang, Robert M. Waterhouse, Yifan Zhai, Cheng Sun   +14 more
wiley   +1 more source

Understanding biological control function and trophic interaction dynamics of an artificially released predatory bug by DNA metabarcoding

Insect Science, EarlyView.
This study investigated the dietary composition of Sycanus bifidus, a generalist predator of the assassin bug that is artificially released into citrus orchards, and uncovered its trophic structure across various pest species using metabarcoding‐based molecular gut content analysis.
Weidong Huang, Suyi Chen, Zihua Zhao, Chunyan Yang, Anxian Shi, Hu Li, Yuange Duan, Fan Song, Hailin Yang, Wanzhi Cai   +9 more
wiley   +1 more source

Effect of the microbiome on pathogen susceptibility across four Drosophilidae species

Insect Science, EarlyView.
Four Drosophilidae species were used to investigate how variation in the host microbiome influences susceptibility to infection. Microbial composition and abundance differed among species and treatments. The effects of microbiome manipulation on host survival were both species‐ and pathogen‐specific.
Hongbo Sun, Ben Longdon, Ben Raymond
wiley   +1 more source

Gut Microbiota of Gray Snub‐Nosed Monkeys: Adaptation to Seasonal Variations Through Energy Compensation and Thermogenesis

Integrative Zoology, EarlyView.
Based on metagenome‐assembled genomes (MAGs), the gut microbiota of the gray snub‐nosed monkeys recovered 1229 non‐redundant MAGs. The gut microbiota showed an enhanced capacity to produce energy substrates with increased conversion activity of these substrates during winter.
Yue Sun, Mingyi Zhang, Xiaochen Wang, Xiaolong Huang, Yanze Yu, Huijuan Pan, Haibo Li, Lei Shi, Wei Yang, Chen Zhang, Bo Ding, Xun Liu, Jianfeng Li, Changjiang Qian, Boxing Cheng, Chao Zhang, Jingcheng Ran, Ming Li   +17 more
wiley   +1 more source

Hybridization With a Non‐Native Congener Threatens the Catalan Chub (Squalius laietanus): Optimization of a DNA‐Based Early Warning Tool

Integrative Zoology, EarlyView.
Hybridization with non‐native congeners threatens endemic freshwater fishes. Using a rapid and cost‐effective nuclear DNA assay, we detected widespread hybridization between the Catalan chub (Squalius laietanus) and the non‐native European chub (Squalius cephalus) across S.
Núria Pérez‐Bielsa, Alba Abras, Sandra Heras, Marc Palmada‐Flores, Jose‐Luis García‐Marín   +4 more
wiley   +1 more source

Maximizing eDNA detections of rare marine organisms: A case study of a delphinid species

Methods in Ecology and Evolution, EarlyView.
Abstract Environmental DNA (eDNA) is an emerging tool for surveying marine organisms. Advances in molecular assay designs and bioinformatic methods provide new opportunities for detecting rare species; however, overcoming methodological challenges of rare species detection remains an important obstacle for the widespread deployment of eDNA methods for ...
Nastassia V. Patin, Eiren K. Jacobson, Zachary Gold, Amy M. Van Cise, Julie Dinasquet, Bryce Ellman, Robert H. Lampe, Anne Schulberg, Noelle Bowlin, Ryan Freedman, Erin Satterthwaite, Andrew E. Allen, Brice X. Semmens   +12 more
wiley   +1 more source

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick, Margaretha A. Skowron, Gereon Poschmann, Patrick Petzsch, Ann Kathrin Bergmann, Kai Stühler, Jochen Hecht, Daniel Nettersheim   +7 more
wiley   +1 more source