Results 131 to 140 of about 67,468 (297)

Solid Phase Synthesis and TAR RNA-Binding Activity of Nucleopeptides Containing Nucleobases Linked to the Side Chains via 1,4-Linked-1,2,3-triazole

Biomedicines
Nucleopeptides (NPs) represent synthetic polymers created by attaching nucleobases to the side chains of amino acid residues within peptides. These compounds amalgamate the characteristics of peptides and nucleic acids, showcasing a unique ability to ...
Piotr Mucha, Małgorzata Pieszko, Irena Bylińska, Wiesław Wiczk, Jarosław Ruczyński, Katarzyna Prochera, Piotr Rekowski   +6 more
doaj   +1 more source

Printing to Fight Antimicrobial Resistance Through Nano/Microstructured Platforms

The Chemical Record, EarlyView.
Additive manufacturing enables the rational design of structured antimicrobial platforms across multiple length scales, from nanofibrous scaffolds and droplet microreactors to 3D and 4D printed constructs. By engineering confinement, interfacial chemistry, and stimuli‐responsive release, these systems exert localized action through complementary ...
Giorgia Puleo, Silvia Orecchio, Dario Savoca, Claudia Pellerito, Vittorio Ferrara, Vincenzo Piscopo, Sebastiano Alberto Fortuna, Alessandra Giardina, Bruno Pignataro, Paola Costanzo, Floriana Campanile, Giuseppe Arrabito   +11 more
wiley   +1 more source

Thermal dissection of lentil seedling amine oxidase domains by differential scanning calorimetry [PDF]

The relationships between the structural and energetic domains of lentil seedling amine oxidase (LSAO) were investigated using modifiers that target the active site and the carbohydrate moiety of the enzyme.
صبوری, علی اکبر, هاشم نیا, صدیقه, موسوی موحدی, علی اکبر, امانی, مجتبی, فلوریس, جیووانی, احمد, فیضان, مورا, آنا, یوسفی, رضا, موسوی نژاد, سیده زهرا, حکیم الهی, غلامحسین, رضایی طاویرانی, مصطفی   +10 more
core  

Fluorescent and electrochemical paper based dual sensor for simple and low cost detection of human papillomavirus DNA without denaturation

Scientific Reports
Tedious steps for double-stranded DNA (dsDNA) denaturation into single-stranded DNA (ssDNA) are necessary for most DNA samples for probe-based hybridization assays, which complicates the detection process.
Panon Tungkunaruk, Sakda Jampasa, Jutamas Jaewjaroenwattana, Prinjaporn Teengam, Kotchakorn Supabowornsathit, Tirayut Vilaivan, Orawon Chailapakul, Janjira Panchompoo   +7 more
doaj   +1 more source

Establishment and Application of MCRV Detection Method for Larvae of Mud Crab, Scylla paramamosain

Progress in Fishery Sciences
Mud crab reovirus (MCRV) present in Scylla paramamosain larvae poses notable risks to the late stage of mud crab aquaculture. The cultivation of MCRV-free larvae and prevention of virus transmission at its source have become critical issues that must be ...
Xiyu JIN, Shouhu LI, Yue WU, Xu CHU, Wei WANG, Wenhong FANG, Xincang LI   +6 more
doaj   +1 more source

Novel reference gene microseminoprotein‐beta based prostate cancer antigen 3 urine test: Enhanced diagnostic performance for prostate cancer and feasibility of non‐digital rectal examination urine sampling

UroPrecision, EarlyView.
Abstract Background The diagnosis of prostate cancer (PCa) is limited by low specificity and invasiveness. This study aims to establish a highly accurate, noninvasive reverse transcription‐quantitative polymerase chain reaction (RT‐qPCR)‐based urinary prostate cancer antigen 3 (PCA3) assay system and explore the feasibility of using first‐morning urine
Jianglei Xu, Lu Yang, Cong Shi, Yiwei Jiang, Jing Chen, Xiaoxiao Sun, Xuejuan Gao, Xian Wang, Jianzhong Jiang, Xiuzhi Duan, Xuchu Wang, Yiyi Xie, Zhixian Yu, Zhihua Tao, Xiaobing Dou, Chunyu Jin   +15 more
wiley   +1 more source

Structural studies of nucleic acids and proteins involved in nucleic acid recognition [PDF]

, 2010
This PhD thesis focuses on the structural analysis of the protein-nucleic acid recognition. In particular the research work has been focalized on two different kinds of proteins and their nucleotide ligands.
Russo Krauss, Irene
core  

Whole‐transcriptome sequencing analyses identified exosomal circular RNAs in the plasma of pancreatic cancer patients as novel blood‐based biomarkers of disease

VIEW, EarlyView.
Pancreatic cancer (PaCa) has a poor prognosis, with low resection rates and high relapse rates, highlighting the urgent need for novel diagnostic biomarkers. Here, we performed whole‐transcriptome sequencing of plasma‐derived exosomes from PaCa patients and identified several differentially expressed circular RNAs (circRNAs).
Xiaomeng He, Yang Di, Lixiang Sun, Zhirong Wu, Mengting Luo, Xin Zhang, Huaqin Sun, Wanli Xu, Wenchuan Wu, Boheng Zhang, Jin Wang   +10 more
wiley   +1 more source

Glass eels and viruses – a lesson learnt from stocking the eastern German Baltic Sea coast

Transboundary and Emerging Diseases, Accepted Article., 2022
Abstract Concerns about Anguillid herpesvirus 1 (AngHV‐1) in European eels, especially due to stocking measures, is increasingly coming into focus and raises questions regarding disease monitoring and prevention. In the past, stocking of AngHV‐1‐positive eels into waters assumed AngHV‐1‐free has led to a rapid increase of infected eels in the wild. For
Laura Kullmann, Mikolaj Adamek, Dieter Steinhagen, Ralf Thiel   +3 more
wiley   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source