Results 131 to 140 of about 5,589,910 (303)

Locked Nucleic Acid (LNA): An Improved Alternative to DNA for Nanoscale ‘On-Surface’ Nucleic Acid Detection [PDF]

, 2019
The research work embodied in the present thesis entitled “Locked Nucleic Acid (LNA): An Improved Alternative to DNA for Nanoscale ‘On-Surface’ Nucleic Acid Detection” deals with the effectiveness of the locked nucleic acid (LNA) probe, which is ...
Mishra, Sourav
core  

Bioinspired Adaptive Surfaces for Intelligent Liquid Manipulation: Progressing From Passive and Active to Hybrid Strategies

Advanced Materials, EarlyView.
This review examines passive, active, and hybrid liquid manipulation strategies, highlighting hybrid approaches as an emerging route to reconcile energy efficiency with adaptive control. By actively reconstructing passive surfaces to store programmable interfacial energy, hybrid systems enable flexible yet low‐power liquid transport, with perspectives ...
Jiaqi Miao, Yiyuan Zhang, Liqiu Wang, Alan C. H. Tsang   +3 more
wiley   +1 more source

Development of nucleic acid-based RAA test strip assay for the rapid detection of foot-and-mouth disease virus

Frontiers in Veterinary Science
Foot-and-mouth disease virus (FMDV) causes blister-like lesions in animals, leading to significant economic losses in animal husbandry. Accurate and rapid detection of FMD is crucial for effective prevention and control.
Wenxian Chen, Xinni Niu, Weijun Zeng, Yiqi Fang, Zixiang Zhu, Lin Yi, Mingqiu Zhao, Hongxing Ding, Shuangqi Fan, Zhaoyao Li, Jinding Chen   +10 more
doaj   +1 more source

Metal–Organic Framework‐Preserved Thermostable Microneedle Patch for Minimally Invasive Detection and Monitoring of Kidney Dysfunction

Advanced Materials, EarlyView.
By growing a conformal ZIF‐8 protective layer directly on antibody‐functionalized microneedles, this work converts a fragile biosensing interface into a thermostable diagnostic platform. The MOF@MN patch enables minimally invasive NGAL detection from dermal ISF while supporting cold‐chain‐independent storage and transport for decentralized kidney ...
Yixuan Wang, Ying Liu, Avishek Debnath, Chuang Li, Zheyu Wang, Gayathri Kondepati, Saketh Balmoori, Jeremiah J. Morrissey, Ying Maggie Chen, Limei Tian, Srikanth Singamaneni   +10 more
wiley   +1 more source

Plant pathogen diagnostics: immunological and nucleic acid-based approaches

, 2004
Accurate disease diagnosis and precise identification of any pathogens involved is an essential prerequisite for understanding plant diseases and controlling them effectively.
Fraaije, B. A., Foster, S. J., Ward, E., McCartney, H. A.   +3 more
core   +1 more source

Polyphenol‐Inspired Materials for Agricultural Applications

Advanced Materials, EarlyView.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu, Omid Mazaheri, Zhixing Lin, Tianzheng Wang, Jingqu Chen, Yuang Gu, Xia Liang, Deli Chen, Frank Caruso   +8 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Iterative Selection of DNA Nanostructures for Cellular Uptake

Advanced Materials, EarlyView.
DNA nanostructures are promising cell targeting delivery vehicles for therapeutics, but the targeting behavior is not fully understood. In this study, libraries of DNA nanostructures that can be amplified and sequenced are combined with cellular uptake as a selection pressure to iteratively refine DNA structures taken up in cells to better understand ...
Anjali Rajwar, Lisa Eichhorn, Jakub Palacka, Sandra Ly, Erik Benson   +4 more
wiley   +1 more source

Lab‐in‐a‐Tube System Integrating Hierarchically Wrinkled Electrodes and DNAzyme‐Functionalized Beads for Diagnosis of Clostridioides difficile Infection

Advanced Materials, EarlyView.
The point‐of‐care diagnosis of Clostridioides difficile infection remains challenging due to reliance on slow culture and amplification‐based methods. A lab‐in‐a‐tube electrochemical biosensor integrating DNAzymes, antifouling magnetic beads, and a hierarchically structured flow cell enables amplification‐ and culture‐free detection directly in stool ...
Survanshu Saxena, Soyeon Lee, Youngeun Choi, Jonathan L'Heureux‐Hache, Jiaying Liu, Sadman Sakib, Sara M. Imani, Marek Smieja, Yingfu Li, Todd Hoare, Leyla Soleymani   +10 more
wiley   +1 more source

Structural and Dynamic Properties of Lipid‐Coated Gold Nanoparticles

Advanced Materials Interfaces, EarlyView.
Atomistic molecular dynamics simulations reveal how lipid chemistry governs the behavior of coatings on the surface of a gold nanoparticle. Variations in headgroup charge and acyl‐chain saturation produce distinct monolayer‐like lipid organization, ranging from compact, ordered coatings to extended, dynamic shells. These findings establish a foundation
Kalpani A. Mirihana, Rashad Kariuki, Charlotte E. Conn, Aaron Elbourne, Andrew J. Christofferson   +4 more
wiley   +1 more source