Results 251 to 260 of about 114,253 (306)

Hybridization of Peptide Nucleic Acid

Biochemistry, 1998
The thermodynamics of hybridization and the conformations of decameric mixed purine-pyrimidine sequence PNA/PNA, PNA/DNA, and DNA/DNA duplexes have been studied using fluorescence energy transfer (FET), absorption hypochromicity (ABS), isothermal titration calorimetry (ITC), and circular dichroism (CD) techniques.
Ratilainen, T., Holmén, A., Tuite, E., Haaima, G., Christensen, L., Nielsen, Peter Eigil, Nordén, B.   +6 more
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In situ nucleic acid hybridization

Survey of Ophthalmology, 1989
Nucleic acid hybridization is a recently developed laboratory technique that allows identification of the genetic material in tissue specimens. The role of the nucleic acids DNA and RNA in cellular function and disease is reviewed, followed by discussion of nucleic acid detection techniques.
W R, Freeman, C A, Wiley
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Labelling nucleic acids for hybridization

Nature, 1987
The enormous utility of labelled nucleic acid probes has encouraged the development, over the past decade, of many efficient and reliable labelling methods.
M W, Cunningham, C R, Mundy
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ENVIRONMENTAL APPLICATION OF NUCLEIC ACID HYBRIDIZATION

Annual Review of Microbiology, 1990
INTRODUCTION 625 NUCLEIC ACID HYBRIDIZATION PROBE TECHNOLOGy . . . . . . . . . . . . .. , .. "" ... "... 627 PROBE LABELLING AND HYBRID DETECTION."" .. " , 629 Radioactive Methods . . . . ... . ... . . . . . . . . . . . . .. . .. . . . . . . . . . . . . . . . , 629 NOllradioactive Methods . ,. .. . . . . . . . . . .. . . . . . . . .. . . . .. . . .
G S, Sayler, A C, Layton
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In situ hybridization of nucleic acids

Trends in Biochemical Sciences, 1976
Hybridization of radioactive nucleic acid sequences can be carried out with DNA in cytological preparations. By autoradiography distinct DNA sequences can then be localized in eukaryotic chromosomes.
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Nucleic acid hybridization in viral Hepatitis research

La Ricerca in Clinica e in Laboratorio, 1988
Nucleic acid hybridization is extremely important in viral hepatitis research and the newly emerging techniques are now becoming an indispensable resource also in the diagnostic laboratory. This paper provides information on methods currently used for detection of viral nucleic acids with special emphasis on the importance of hepatitis B virus DNA in ...
Maran E, Piantino P, Brunetto MR, Chiaberge E, Bonino F.   +4 more
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Fluorescent Nucleic Acid Hybridization Methods.

SPIE Proceedings, 1989
In the last several years a number of approaches have been developed that permit detection of nucleic acid hybridization using fluorescence techniques. These have several advantages over the previously available radioactive procedures. Among these are much higher spatial resolution, the speed with which the results are available, the reduced hazard ...
D. Pinkel, J. Gray, R. Segraves, F. Waldman, B. Trask, L. C. Yu, D. Eastmond, P. Dean   +7 more
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New Developments in Nucleic Acid Hybridization

1985
Nucleic acid hybridization is widely used for scientific applications in specialized laboratories. This paper describes hybridization probes that can be prepared with less specialized equipment. A new indirect 'sandwich' hybridization test is described which allows the use of only one universally usable labelled probe for hybridization tests with ...
H, Wolf, M, Haus, U, Leser, S, Modrow, M, Motz, S Y, Gu, N, Falser, I, Bandlow, W, Richter, R, Pathmanathan   +9 more
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Nucleic acid hybridization in viral diagnosis

Clinical Biochemistry, 1990
Since 1982, numerous studies have been published utilizing a variety of hybridization techniques to detect viral nucleic acid directly in clinical specimens and in tissue sections. However, hybridization techniques are still not widely used in the clinical laboratory.
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