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The nucleic acid reactions on the nanomaterials surface for biomedicine. [PDF]
Xue Z+5 more
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Block copolymer-assembled nanopore arrays enable ultrasensitive label-free DNA detection.
Fornerod MJJ+6 more
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Biointerface Engineering with Nucleic Acid Materials for Biosensing Applications
Advanced Functional Materials, 2022Molecular recognition at the biointerface plays a critical role in sensing molecular interactions (e.g., DNA hybridization) and extracellular changes, which can directly affect the detection performance of biosensors (e.g., sensitivity, specificity, and ...
Shi Shi+7 more
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Nucleic Acid Tests for Clinical Translation.
Chemical Reviews, 2021Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are natural biopolymers composed of nucleotides that store, transmit, and express genetic information.
Min Li+7 more
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Hybridization of Peptide Nucleic Acid
Biochemistry, 1998The thermodynamics of hybridization and the conformations of decameric mixed purine-pyrimidine sequence PNA/PNA, PNA/DNA, and DNA/DNA duplexes have been studied using fluorescence energy transfer (FET), absorption hypochromicity (ABS), isothermal titration calorimetry (ITC), and circular dichroism (CD) techniques.
Ratilainen, T.+6 more
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In situ hybridization of nucleic acids [PDF]
Hybridization of radioactive nucleic acid sequences can be carried out with DNA in cytological preparations. By autoradiography distinct DNA sequences can then be localized in eukaryotic chromosomes.
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In situ nucleic acid hybridization
Survey of Ophthalmology, 1989Nucleic acid hybridization is a recently developed laboratory technique that allows identification of the genetic material in tissue specimens. The role of the nucleic acids DNA and RNA in cellular function and disease is reviewed, followed by discussion of nucleic acid detection techniques.
William R. Freeman, Clayton A. Wiley
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Labelling nucleic acids for hybridization
Nature, 1987The enormous utility of labelled nucleic acid probes has encouraged the development, over the past decade, of many efficient and reliable labelling methods.
C. R. Mundy, M. W. Cunningham
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Identification of foodborne pathogens by nucleic acid hybridization [PDF]
Nucleic acid hybridization methods have been developed and used to identify microorganisms in foods. Tests performed on mixed cultures save the time required to establish pure cultures. Enterotoxigenic or invasive strains of foodborne bacterial pathogens are detected with probes that identify genes responsible for virulence.
Walter E. Hill, Stacye P. Keasler
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ENVIRONMENTAL APPLICATION OF NUCLEIC ACID HYBRIDIZATION
Annual Review of Microbiology, 1990INTRODUCTION 625 NUCLEIC ACID HYBRIDIZATION PROBE TECHNOLOGy . . . . . . . . . . . . .. , .. "" ... "... 627 PROBE LABELLING AND HYBRID DETECTION."" .. " , 629 Radioactive Methods . . . . ... . ... . . . . . . . . . . . . .. . .. . . . . . . . . . . . . . . . , 629 NOllradioactive Methods . ,. .. . . . . . . . . . .. . . . . . . . .. . . . .. . . .
Alice C. Layton, Gary S. Sayler
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