Results 41 to 50 of about 261,306 (113)

Electrically Guided DNA Immobilization and Multiplexed DNA Detection with Nanoporous Gold Electrodes. [PDF]

, 2018
Molecular diagnostics have significantly advanced the early detection of diseases, where the electrochemical sensing of biomarkers (e.g., DNA, RNA, proteins) using multiple electrode arrays (MEAs) has shown considerable promise.
Daggumati, Pallavi, Li, Zidong, Seker, Erkin, Veselinovic, Jovana   +3 more
core   +3 more sources

Identification of antisense nucleic acid hybridization sites in mRNA molecules with self-quenching fluorescent reporter molecules [PDF]

, 2005
We describe a physical mRNA mapping strategy employing fluorescent self-quenching reporter molecules (SQRMs) that facilitates the identification of mRNA sequence accessible for hybridization with antisense nucleic acids in vitro and in vivo, real time ...
Do, Bao T., Gewirtz, Alan M., Gifford, Lida K., Greenham, Paul, Jordan, David, Kalota, Anna, Lu, Ponzy, Opalinska, Joanna B., Pattanayak, Vikram, Robbins, Michelle, Rodriguez, Lesbeth C., Vernovsky, Kathy   +11 more
core   +2 more sources

Nucleic acid-based fluorescent probes and their analytical potential [PDF]

, 2010
It is well known that nucleic acids play an essential role in living organisms because they store and transmit genetic information and use that information to direct the synthesis of proteins.
A Dembska, A Okamoto, A Ono, A Peracchi, A Ramos, A Tsourkas, A Tsuji, AA Marti, AA Marti, AA Martí, AD Elington, AK Tong, AO Crockett, AW Oliver, B Dubertret, B Hoefelschweiger, B Juskowiak, B Juskowiak, BC Yin, Bernard Juskowiak, C Liu, C Shi, C Tuerk, C Wanninger-Weiss, C-Y Zhang, CH Lu, CJ Yang, CJ Yang, CJ Yang, CYJ Yang, D Lindegaart, D Mann, D Whitcombe, DE Huizenga, DJ French, DP Morse, DS Wilson, E Heyduk, E Westhof, EJ Merino, F He, F Li, FM Winnik, G Gokulrangan, GT Hwang, H Dong, H Hayashida, H Orum, H Ozaki, H Uehara, H Ueyama, H Urata, H Wang, HW Chen, I German, I Nazarenko, I Nazarenko, I Nazarenko, IV Kutyavin, J Ciesiolka, J Isacsson, J Li, J Liu, J Liu, J Liu, J Perlette, J Srinivasan, J-L Mergny, J-M Costa, J-P Knemeyer, JA Vet, JC Achenbach, JH Kim, JJ Li, JJ Li, JL Mergny, JM Thomas, JR Lakowicz, JS Jepsen, JW Liu, K Ebata, K Fujimoto, K Gehring, K Matsumoto, K Yamana, K Yamana, K Yamana, K Yamana, L Peng, L Wang, LC Bock, LE Morrison, LE Morrison, LG Lee, LN Krasnoperov, M Egholm, M Kosuge, M Kubista, M Levy, M Manoharan, M Massey, M Masuko, M Sauer, MA Innis, MJ Heller, MN Stojanovic, MN Stojanovic, N Carmi, N Hamaguchi, N Kamekawa, N Li, N Svanvik, N Svanvik, O Seitz, P Conlon, P Zhang, P Zhang, PJ Santangelo, PJ Santangelo, PM Holland, PY Kwok, R Haner, R Kumar, R Nutiu, R Nutiu, R Nutiu, R Nutiu, R Stoltenburg, R Yamamoto, R Yamamoto, RA Cardullo, RA Potyrailo, RF Macaya, RM Clegg, RM Clegg, S Jhaveri, S Modi, S Nagatoishi, S Nagatoishi, S Neidle, S Neidle, S Sandhya, S Sueda, S Takenaka, S Tyagi, S Tyagi, S Tyagi, S Zhang, SA Kushon, SAE Marras, SAE Marras, SC Johnson, SD Mendonsa, SK Silverman, SM Kerwin, T Simonsson, T Simonsson, T Takahashi, TS Misono, W Chiuman, W Guschlbauer, WJ Wang, WR Algar, X Fang, X Fang, X Li, XH Fang, XH Peng, Y Chen, Y Ito, Y Kim, Y Li, Y Sei-Iida, Y Wang, Y Xu, YJ Seo, Z Liu, Z Tang   +177 more
core   +2 more sources

A new formalism for calculation of the partition function of single stranded nucleic acids [PDF]

arXiv, 2005
A new formalism for calculation of the partition function of single stranded nucleic acids is presented. Secondary structures and the topology of structure elements are the level of resolution that is used. The folding model deals with matches, mismatches, symmetric and asymmetric interior loops, stacked pairs in loop and dangling end regions, multi ...
arxiv  

Studies on Nucleic Acid Reassociation Kinetics: Retarded Rate of Hybridization of RNA with Excess DNA [PDF]

, 1977
The rate of reaction of excess double-stranded bacteriophage phi X174 and plasmid RSF2124 DNA drivers with enzymatically synthesized asymmetric RNA tracers was measured. Other reactions were carried out with excess Escherichia coli DNA and E.
Britten, Roy J., Davidson, Eric H., Galau, Glenn A., Smith, Michael J.   +3 more
core   +1 more source

Fluorescent labeling of plasmid DNA and mRNA : gains and losses of current labeling strategies [PDF]

, 2016
Live-cell imaging has provided the life sciences with insights into the cell biology and dynamics. Fluorescent labeling of target molecules proves to be indispensable in this regard. In this Review, we focus on the current fluorescent labeling strategies
Braeckmans, Kevin, Remaut, Katrien, Rombouts, Koen   +2 more
core   +2 more sources

Stacking correlation length in single-stranded DNA [PDF]

Nucleic Acids Research, 2024
Base stacking is crucial in nucleic acid stabilization, from DNA duplex hybridization to single-stranded DNA (ssDNA) protein binding. While stacking energies are tiny in ssDNA, they are inextricably mixed with hydrogen bonding in DNA base pairing, making their measurement challenging. We conduct unzipping experiments with optical tweezers of short poly-
arxiv   +1 more source

Surface Micro-Patterned Biofunctionalized Hydrogel for Direct Nucleic Acid Hybridization Detection. [PDF]

Biosensors (Basel), 2023
Zezza P, Lucío MI, Fernández E, Maquieira Á, Bañuls MJ.   +4 more
europepmc   +1 more source

Flexibility of nucleic acids: from DNA to RNA [PDF]

arXiv, 2015
The structural flexibility of nucleic acids plays a key role in many fundamental life processes, such as gene replication and expression, DNA-protein recognition, and gene regulation. To obtain a thorough understanding of nucleic acid flexibility, extensive studies have been performed using various experimental methods and theoretical models.
arxiv  

Using Peptide Nucleic Acid Hybridization Probes for Qualitative and Quantitative Analysis of Nucleic Acid Therapeutics by Capillary Electrophoresis. [PDF]

Anal Chem, 2023
Hutanu A, Signori C, Moritz B, Gregoritza M, Rohde A, Schwarz MA.   +5 more
europepmc   +1 more source