Results 201 to 210 of about 48,779 (251)

A promising frontier of circulating messenger RNA in liquid biopsy: From mechanisms to clinical applications

International Journal of Cancer, EarlyView.
Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li, Yijin Yu, Guangyue Liu, Shunhong Zhang, Chenchen Luo, Saidi Hu, Siran Wan, Linyong Zhao   +7 more
wiley   +1 more source

Enhanced Outer Membrane Vesicle Production in <i>Escherichia coli</i>: From Metabolic Network Model to Designed Strain Lipidomic Profile. [PDF]

Int J Mol Sci
Ruiz-Moreno HA, Valderrama-Rincon JD, Cala MP, Fernández-Niño M, Valderruten Cajiao M, Villegas-Torres MF, González Barrios AF.   +6 more
europepmc   +1 more source

ADAR1 mRNA quantification for predicting HSIL in persons with HIV and abnormal anal cytology

International Journal of Cancer, EarlyView.
What's New? This study introduces ADAR1 mRNA quantification as a promising biomarker for improving high‐grade squamous intraepithelial lesion (HSIL) prediction in HIV‐positive individuals with abnormal anal cytology. With 92% specificity, it reduces unnecessary high‐resolution anoscopies (HRA) by 77%, offering a more efficient and targeted screening ...
Melissa Bello‐Perez, Paula Mascarell, Marta Fernández‐González, Jose Alberto García, Ana Gutiérrez‐Ortiz de la Tabla, Christian Ledesma, Alba De la Rica, Antonio Galiana, Leo López, Maria Dolores Ocete, Carme Salvador, Concepción Gimeno, Javier García‐Abellán, Sergio Padilla, Félix Gutiérrez, Mar Masiá   +15 more
wiley   +1 more source

Advancements and Prospects in DNA-Based Bioanalytical Technology for Environmental Toxicant Detection. [PDF]

JACS Au
Liu S, Xu B, Li C, Ren Y, Gan H, Kuang S, Lei C, Nie Z.   +7 more
europepmc   +1 more source

Gut microbiota and tuberculosis

iMeta, EarlyView.
This review explores the intricate relationship between gut microbiota (GM) and tuberculosis (TB). The figure illustrates the bidirectional effects between GM dynamics and TB progression, as well as the interactions between the GM and antituberculosis drugs.
Yanhua Liu, Ling Yang, Maryam Meskini, Anjana Goel, Monique Opperman, Sagar Singh Shyamal, Ajay Manaithiya, Meng Xiao, Ruizi Ni, Yajing An, Mingming Zhang, Yuan Tian, Shuang Zhou, Zhaoyang Ye, Li Zhuang, Linsheng Li, Istuti Saraswat, Ankita Kar, Syed Luqman Ali, Shakir Ullah, Syed Yasir Ali, Shradha Kaushik, Tianmu Tian, Mingyang Jiao, Shujun Wang, Giulia Ghisleni, Alice Armanni, Sara Fumagalli, WenYu Wang, Chao Cao, Maria Carpena, Miguel A. Prieto, Antonia Bruno, Chanyuan Jin, Hanqing Hu, Yuhang Zhang, Ilse du Preez, Ashok Aspatwar, Lingxia Zhang, Wenping Gong   +39 more
wiley   +1 more source

Taking a closer look at matrix vesicle biogenesis. [PDF]

J Bone Miner Res
Clews C, Dillon S, Nudelman F, Farquharson C, Stephen LA.   +4 more
europepmc   +1 more source

Akkermansia muciniphila‐derived hypoacylated rough‐type lipopolysaccharides alleviate diet‐induced obesity via activation of TLR4−IL‐23−IL‐22 immune axis

iMeta, EarlyView.
This study demonstrates that hypoacylated, rough‐type lipopolysaccharides (LPS) derived from Akkermansia muciniphila strain HW07 (ALPS) alleviates diet‐induced obesity. ALPS acts as a weak TLR4 agonist and significantly reduces weight gain, improves metabolic parameters, and restores gut barrier integrity in obese mice.
Li Sun, Yuting Zhang, Wang Dong, Jingzu Sun, Tao Wang, Fei Shao, Huanqin Dai, Junjie Han, Wenzhao Wang, Shuo Wang, Tong Zhao, Liangliang Wang, Chang Liu, Shuangjiang Liu, Hongwei Liu   +14 more
wiley   +1 more source

MicroRNA-Based Delivery Systems for Chronic Neuropathic Pain Treatment in Dorsal Root Ganglion. [PDF]

Pharmaceutics
Jackson S, Gigliobianco MR, Casadidio C, Di Martino P, Censi R.   +4 more
europepmc   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

Unraveling the Interplay Between Metabolism and Neurodevelopment in Health and Disease. [PDF]

CNS Neurosci Ther
He Y, Xie K, Yang K, Wang N, Zhang L.
europepmc   +1 more source