Results 31 to 40 of about 492,866 (322)

Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction [PDF]

, 2011
BACKGROUND: Burkholderia cenocepacia is a threatening nosocomial epidemic pathogen in patients with cystic fibrosis (CF) or a compromised immune system. Its high level of antibiotic resistance is an increasing concern in treatments against its infection.
Fang, K., Zhao, H., Changyue Sun, Lam, M.C., Chang, S., Zhang, K., Panda, G., Godinho, M., Martins Dos Santos, V.A.P., Wang, J.   +9 more
core   +2 more sources

Bacteriophage Assembly

Viruses, 2011
Bacteriophages have been a model system to study assembly processes for over half a century. Formation of infectious phage particles involves specific protein-protein and protein-nucleic acid interactions, as well as large conformational changes of ...
Anastasia A. Aksyuk, Michael G. Rossmann
doaj   +1 more source

Gene Loss and Horizontal Gene Transfer Contributed to the Genome Evolution of the Extreme Acidophile “Ferrovum” [PDF]

, 2016
Indexación: Web of Science. Scopus.Acid mine drainage (AMD), associated with active and abandoned mining sites, is a habitat for acidophilic microorganisms that gain energy from the oxidation of reduced sulfur compounds and ferrous iron and that thrive ...
Daniel, Rolf, González, Carolina, Holmes, David S., Mühling, Martin, Poehlein, Anja, Schlömann, Michael, Tischler, Judith S., Ullrich, Sophie R.   +7 more
core   +2 more sources

Translin facilitates RNA polymerase II dissociation and suppresses genome instability during RNase H2- and Dicer-deficiency.

PLoS Genetics, 2022
The conserved nucleic acid binding protein Translin contributes to numerous facets of mammalian biology and genetic diseases. It was first identified as a binder of cancer-associated chromosomal translocation breakpoint junctions leading to the ...
Natalia Gomez-Escobar, Ahad A A Alsaiari, Hanadi A S Alahamadi, Othman Alzahrani, Ellen Vernon, Hussam A E Althagafi, Nasser S Almobadel, David W Pryce, Jane A Wakeman, Ramsay J McFarlane   +9 more
doaj   +1 more source

An all-purine precursor of nucleic acids. [PDF]

Proceedings of the National Academy of Sciences, 1988
The theory is proposed that the pyrimidines in extant nucleic acids are postenzymatic substitutes for their isoelectronic and isogeometric position 3-bonded purine analogs xanthine and isoguanine, which were sibling products in a preenzymatic de novo purine pathway.
openaire   +2 more sources

Synthesis and Regulation of Folate Coenzymes During early Germination in Vigna radiata

Pteridines, 2001
Folate profiles and DNA synthesis were studied during the early germinating period in Vigna radiata. Total folate andmethyl folate forms were increased from 4 to 32 hours during germination period studied.
Kesavan V., Singh N., Pote M.S., Viswanathan G.   +3 more
doaj   +1 more source

Diversity of Endonuclease V: From DNA Repair to RNA Editing

Biomolecules, 2015
Deamination of adenine occurs in DNA, RNA, and their precursors via a hydrolytic reaction and a nitrosative reaction. The generated deaminated products are potentially mutagenic because of their structural similarity to natural bases, which in turn leads
Isao Kuraoka
doaj   +1 more source

Studies on the relation between heme and nucleic acid syntheses in erythroid cell. 3. Nucleolus of erythroblast, changes in relation with cell specialization [PDF]

, 1969
The disappearance of nucleolus has been traced in the rat erythroid cells in relation with the cell specialization under varying conditions, i. e. in anemia with or without treatment by bromouracil and aminopterin.
Shigehisa, Morio
core   +1 more source

Cytotoxicity of three new triazolo-pyrimidine derivatives against the plant trypanosomatid: Phytomonas sp. isolated from Euphorbia characias

Memorias do Instituto Oswaldo Cruz, 2004
There is no effective chemotherapy against diseases caused by Phytomonas sp., a plant trypanosomatid responsible for economic losses in major crops.
Rosa Magán, Clotilde Marín, Juan M Salas, Mario Barrera-Pérez, Maria J Rosales, Manuel Sánchez-Moreno   +5 more
doaj   +1 more source

A new journey of fluorescent carbon dots: A shining star in the realm of nucleic acid dyes

Materials & Design
Nucleic acid dyes play important roles in the quantification and detection of nucleic acids by binding to nucleic acids. However, traditional nucleic acid dyes pose great environmental and economic challenges due to their high price, high toxicity, long ...
Yu Ma, Bin Zhao, Guozhen Yan, Ting Zhou, Zhihua Xu, Zhihan Niu, Zhenghong Xu, Tongtong Zhang, Feng Shi   +8 more
doaj   +1 more source