Results 71 to 80 of about 414,760 (197)

Invading Escherichia coli Genetics with a Xenobiotic Nucleic Acid Carrying an Acyclic Phosphonate Backbone (ZNA).

Journal of the American Chemical Society, 2019
A synthetic orthogonal polymer embracing a chiral acyclic-phosphonate backbone [( S)-ZNA] is presented that uniquely adds to the emerging family of xenobiotic nucleic acids (XNAs).
M. Luo, Elisabetta Groaz, M. Froeyen, V. Pezo, Faten Jaziri, Piotr Leonczak, G. Schepers, J. Rozenski, P. Marlière, P. Herdewijn   +9 more
semanticscholar   +1 more source

Hydrogels of Polycationic Acetohydrazone-Modified Phosphorus Dendrimers for Biomedical Applications: Gelation Studies and Nucleic Acid Loading

Pharmaceutics, 2018
In this work, we report the assemblage of hydrogels from phosphorus dendrimers in the presence of biocompatible additives and the study of their interactions with nucleic acids.
E. Apartsin, A. Grigoryeva, Audrey Malrin-Fournol, E. Ryabchikova, A. Venyaminova, S. Mignani, A. Caminade, J. Majoral   +7 more
semanticscholar   +1 more source

Hydrophobic and hydrophilic au and ag nanoparticles. Breakthroughs and perspectives [PDF]

, 2017
This review provides a broad look on the recent investigations on the synthesis, characterization and physico-chemical properties of noble metal nanoparticles, mainly gold and silver nanoparticles, stabilized with ligands of different chemical nature.
Fratoddi, Ilaria
core   +2 more sources

Characterization of the interaction between the HIV-1 Gag structural polyprotein and the cellular ribosomal protein L7 and its implication in viral nucleic acid remodeling

Retrovirology, 2016
In HIV-1 infected cells, the integrated viral DNA is transcribed by the host cell machinery to generate the full length HIV-1 RNA (FL RNA) that serves as mRNA encoding for the Gag and GagPol precursors.
H. Mekdad, E. Boutant, Hassan Karnib, M. E. Biedma, K. Sharma, Iuliia Malytska, G. Laumond, M. Roy, E. Réal, J. Paillart, C. Moog, J. Darlix, Y. Mély, H. de Rocquigny   +13 more
semanticscholar   +1 more source

Overproduction of PDR3 Suppresses Mitochondrial Import Defects Associated with a TOM70 Null Mutation by Increasing the Expression of TOM72 in Saccharomyces cerevisiae [PDF]

, 2001
Most mitochondrial proteins are synthesized with cleavable amino-terminal targeting signals that interact with the mitochondrial import machinery to facilitate their import from the cytosol.
Bedwell, David M., Hájek, Petr, Koh, Julie Y.   +2 more
core   +1 more source

A new journey of fluorescent carbon dots: A shining star in the realm of nucleic acid dyes

Materials & Design
Nucleic acid dyes play important roles in the quantification and detection of nucleic acids by binding to nucleic acids. However, traditional nucleic acid dyes pose great environmental and economic challenges due to their high price, high toxicity, long ...
Yu Ma, Bin Zhao, Guozhen Yan, Ting Zhou, Zhihua Xu, Zhihan Niu, Zhenghong Xu, Tongtong Zhang, Feng Shi   +8 more
doaj  

Backbone-free duplex-stacked monomer nucleic acids exhibiting Watson-Crick selectivity. [PDF]

, 2018
We demonstrate that nucleic acid (NA) mononucleotide triphosphates (dNTPs and rNTPs), at sufficiently high concentration and low temperature in aqueous solution, can exhibit a phase transition in which chromonic columnar liquid crystal ordering ...
Bellini, Tommaso, Clark, Noel A, Fraccia, Tommaso P, Hayden, Emily, Smith, Gregory P, Todisco, Marco, Zanchetta, Giuliano, Zhu, Chenhui   +7 more
core   +1 more source

Shedding light on gene therapy: Carbon dots for the minimally invasive image-guided delivery of plasmids and noncoding RNAs - A review

Journal of Advanced Research, 2019
Recently, carbon dots (CDs) have attracted great attention due to their superior properties, such as biocompatibility, fluorescence, high quantum yield, and uniform distribution.
Reza Mohammadinejad, Arezoo Dadashzadeh, Saeid Moghassemi, Milad Ashrafizadeh, Ali Dehshahri, Abbas Pardakhty, Hosseinali Sassan, Seyed-Mojtaba Sohrevardi, Ali Mandegary   +8 more
doaj  

Developmental assembly of multi-component polymer systems through interconnected synthetic gene networks in vitro

Nature Communications
Living cells regulate the dynamics of developmental events through interconnected signaling systems that activate and deactivate inert precursors. This suggests that similarly, synthetic biomaterials could be designed to develop over time by using ...
Daniela Sorrentino, Simona Ranallo, Francesco Ricci, Elisa Franco   +3 more
doaj   +1 more source

Polyamines and nucleic acid metabolism in chick embryo. Incorporation of labelled precursors into nucleic acids of subcellular fractions and polyribosomal patterns [PDF]

, 1968
G. Moruzzi, Bruno Barbiroli, C. M. Caldarera   +2 more
openalex   +1 more source