Results 131 to 140 of about 192,096 (245)

Cryomicroneedle Arrays for Biotherapeutics Delivery

Small Science, Volume 5, Issue 8, August 2025.
CryoMNs for biotherapeutic delivery to treat various diseases. CryoMNs: cryomicroneedles. Biotherapy offers a promising approach for treating a variety of diseases. However, the lack of advanced delivery systems remains a significant barrier to improve the efficacy, safety, and cost‐effectiveness of biotherapeutics.
Chunli Yang, Li Zhang, Angxi Zhou, Siyi Wang, Ya Ren, Maya Xiang, Run Tian, Yang Yu, Rong Li, Maling Gou   +9 more
wiley   +1 more source

Design of mismatch closure for enhanced specificity in DNA strand displacement reactions. [PDF]

Nucleic Acids Res
Yu H, Han X, Zhang L, Yin N, Wang L, Lv K, Wu Y, Bai D, Wang W, Huang Y, Hu X, Weng Z, Zhang C, Yang G, Chen T, Xie G.   +15 more
europepmc   +1 more source

Metabolic Redox Coupling Controls Methane Production in Permafrost‐Affected Peatlands Through Organic Matter Quality‐Dependent Energy Allocation

Global Change Biology, Volume 31, Issue 8, August 2025.
Scientists studied how microorganisms in permafrost‐affected peatland ecosystems process organic matter to predict greenhouse gas emissions. Using advanced molecular techniques, they discovered that the chemical quality of organic compounds determines whether microbes produce more or less methane and other greenhouse gases. This research provides a new
John A. Bouranis, Bridget B. McGivern, Ghiwa Makke, Sophie K. Jurgensen, Samantha H. Bosman, Brooke Stemple, Jeffrey P. Chanton, Kelly C. Wrighton, Malak M. Tfaily   +8 more
wiley   +1 more source

The Possible Crystallization Process in the Origin of Bacteria, Archaea, Viruses, and Mobile Elements. [PDF]

Biology (Basel)
Yoshimura A, Seki M.
europepmc   +1 more source

Exploring Sulfate as an Alternative Electron Acceptor: A Potential Strategy to Mitigate N2O Emissions in Upland Arable Soils

Global Change Biology, Volume 31, Issue 8, August 2025.
This study explored the use of sulfate‐based soil amendments as a new method to mitigate N2O—a powerful greenhouse gas—from agricultural soils. Laboratory and field experiments showed sulfate treatments significantly lowered N2O emissions without negatively affecting crop yields, mainly by altering soil microbial processes.
Hyun Ho Lee, Hanbeen Kim, Ye Lim Park, Marcus A. Horn, Jeongeun Kim, Jaehyun Lee, Sakae Toyoda, Jeongeun Yun, Hojeong Kang, Sang Yoon Kim, Jinho Ahn, Chang Oh Hong   +11 more
wiley   +1 more source

Programmable Single-Stranded Circular Antisense Oligonucleotides for Multitarget Gene Therapy. [PDF]

JACS Au
Pan Y, Li X, Zhu C, Wang M, Wu Y, Xu R, Wu J, Chen R, Jiang Y, Tian B, Dong Y, Liu D.   +11 more
europepmc   +1 more source

Solvation, geometry, and assembly of the tobacco mosaic virus. [PDF]

PNAS Nexus
Spirandelli I, Evans ME.
europepmc   +1 more source

Direct SERS Detection of Nucleic Acids in the Presence of Spermine: A Unified Nanoparticle Platform Allows for the Elucidation of Surface Adsorption Hierarchies. [PDF]

J Phys Chem C Nanomater Interfaces
Deriu C, Fabris L.
europepmc   +1 more source

Probe‐capture targeted next‐generation sequencing: A novel approach for pathogen and antimicrobial resistance detection in sepsis

Clinical and Translational Discovery, Volume 5, Issue 4, August 2025.
Chitra Ravi, Adam D. Irwin, Patrick N. A. Harris   +2 more
wiley   +1 more source

Tailored Watson–Crick Pairing Partners for Xanthosine in RNA

Chemistry – A European Journal, Volume 31, Issue 42, July 25, 2025.
RNAs with kappa‐xanthosine (K–X) or 2‐iminocytidine‐xanthosine (2imC–X) base pairs form stable double helices that have higher melting temperatures than those of the A–U or G–U references. Access to these novel 2imC‐modified RNAs is possible through the mild, selective chemical conversion of 2‐thiocytidine RNA precursors.
Stefan Mair, Anna Rázková, Karl Brillet, Catherina Gasser, Eric Ennifar, Ronald Micura   +5 more
wiley   +1 more source