Results 11 to 20 of about 192,096 (245)
Thermodynamics of force-dependent folding and unfolding of small protein and nucleic acid structures [PDF]
Integrative Biology, 2015 In this paper, we outline the theoretical framework for understanding the equilibrium force-dependent folding and unfolding transitions of protein domains and small nucleic acid structures, both having small rigid folded structures and highly flexible ...
Mingxi Yao, Hu Chen, Jie Yan
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A more unified picture for the thermodynamics of nucleic acid duplex melting: A characterization by calorimetric and volumetric techniques [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1999 We use a combination of calorimetric and volumetric techniques to detect and to characterize the thermodynamic changes that accompany helix-to-coil transitions for five polymeric nucleic acid duplexes. Our calorimetric measurements reveal that melting of
Tigran V. Chalikian +3 more
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What Controls the Hybridization Thermodynamics of Spherical Nucleic Acids? [PDF]
Journal of the American Chemical Society, 2015 The hybridization of free oligonucleotides to densely packed, oriented arrays of DNA modifying the surfaces of spherical nucleic acid (SNA)-gold nanoparticle conjugates occurs with negative cooperativity; i.e., each binding event destabilizes subsequent ...
Pratik S. Randeria +6 more
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, 2016 In the 1950’s, the research findings of James Watson, Francis Crick, Rosalind Franklin, and Maurice Wilkins led to the discovery of the deoxyribonucleic acid (DNA) double-helix conformation [1,2].
Fidelis Manyanga
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Nucleic Acid Binding Thermodynamics and Functions of DNA Polymerases
, 2013 ................................................................................................................................... iv CHAPTER 1. GENERAL INTRODUCTION ...............................................................................1 1.1 ...
Hiromi Brown
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Thermodynamics of Nucleic Acid Structural Modifications for Biotechnology Applications
, 2011 The repertoire of chemistry available to native nucleotides in DNA and RNA is limited to the purine and pyrimidine functional groups, along with the special role of the 2’-hydroxyl of RNA. The nucleobases have exocyclic amino groups and imines, neither of which is highly reactive or a good candidate for catalytic function.
Stefan Franzen
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Expanding the Functions of KHSRP Protein: Insights into DNA G‐Quadruplex Binding [PDF]
Advanced ScienceKHSRP (KH‐type splicing regulatory protein) is a multifunctional nucleic acid‐binding protein that regulates various cellular processes, with critical roles in controlling gene expression.
Pasquale Russomanno +9 more
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Editorial: Thermodynamics and structure of nucleic acids with modified bases [PDF]
Biopolymers, 2002 Luis A. Marky
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