Results 11 to 20 of about 191,094 (249)

A more unified picture for the thermodynamics of nucleic acid duplex melting: A characterization by calorimetric and volumetric techniques [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 1999
We use a combination of calorimetric and volumetric techniques to detect and to characterize the thermodynamic changes that accompany helix-to-coil transitions for five polymeric nucleic acid duplexes. Our calorimetric measurements reveal that melting of
Tigran V. Chalikian, Jens Völker, Georg Plum, Kenneth J. Breslauer   +3 more
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What Controls the Hybridization Thermodynamics of Spherical Nucleic Acids? [PDF]

Journal of the American Chemical Society, 2015
The hybridization of free oligonucleotides to densely packed, oriented arrays of DNA modifying the surfaces of spherical nucleic acid (SNA)-gold nanoparticle conjugates occurs with negative cooperativity; i.e., each binding event destabilizes subsequent ...
Pratik S. Randeria, Matthew R. Jones, Kevin L. Kohlstedt, Resham J. Banga, Mónica Olvera de la Cruz, George C. Schatz, Chad A. Mirkin   +6 more
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Use of Differential Scanning Calorimetry (DSC) to Study the Thermodynamics of DNA-Based Interactions and Nucleic Acid-Based Therapeutics

, 2016
In the 1950’s, the research findings of James Watson, Francis Crick, Rosalind Franklin, and Maurice Wilkins led to the discovery of the deoxyribonucleic acid (DNA) double-helix conformation [1,2].
Fidelis Manyanga
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Nucleic Acid Binding Thermodynamics and Functions of DNA Polymerases

, 2013
................................................................................................................................... iv CHAPTER 1. GENERAL INTRODUCTION ...............................................................................1 1.1 ...
Hiromi Brown
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Thermodynamics of Nucleic Acid Structural Modifications for Biotechnology Applications

, 2011
The repertoire of chemistry available to native nucleotides in DNA and RNA is limited to the purine and pyrimidine functional groups, along with the special role of the 2’-hydroxyl of RNA. The nucleobases have exocyclic amino groups and imines, neither of which is highly reactive or a good candidate for catalytic function.
Stefan Franzen
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Expanding the Functions of KHSRP Protein: Insights into DNA G‐Quadruplex Binding [PDF]

Advanced Science
KHSRP (KH‐type splicing regulatory protein) is a multifunctional nucleic acid‐binding protein that regulates various cellular processes, with critical roles in controlling gene expression.
Pasquale Russomanno, Pasquale Zizza, Linda Cerofolini, Federica D'Aria, Sara Iachettini, Serena Di Vito, Annamaria Biroccio, Jussara Amato, Marco Fragai, Bruno Pagano   +9 more
doaj   +2 more sources

Editorial: Thermodynamics and structure of nucleic acids with modified bases [PDF]

Biopolymers, 2002
Luis A. Marky
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Thermodynamics of nucleic acids

Drug Delivery System, 2021
Masayuki Oda
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On the thermodynamics and kinetics of the cooperative binding of bacteriophage T4-coded gene 32 (helix destabilizing) protein to nucleic acid lattices

Biophysical Journal, 1980
S C Kowalczykowski, Nils Lönberg, John W. Newport, Leland S. Paul, Peter H. von Hippel   +4 more
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Thermodynamic analysis of Zα domain-nucleic acid interactions [PDF]

Biochemical Journal, 2022
AbstractDNA/RNA molecules adopting the left-handed conformation (Z-form) have been attributed with immunogenic properties. However, their biological role and importance has been a topic of debate for many years. The discovery of Z-DNA/RNA binding domains (Zα domains) in varied proteins that are involved in the innate immune response, such as the ...
Bharath Srinivasan, Krzysztof Kuś, Alekos Athanasiadis   +2 more
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