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What Controls the Hybridization Thermodynamics of Spherical Nucleic Acids? [PDF]
Journal of the American Chemical Society, 2015 The hybridization of free oligonucleotides to densely packed, oriented arrays of DNA modifying the surfaces of spherical nucleic acid (SNA)-gold nanoparticle conjugates occurs with negative cooperativity; i.e., each binding event destabilizes subsequent ...
Pratik S. Randeria +6 more
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, 2016 In the 1950’s, the research findings of James Watson, Francis Crick, Rosalind Franklin, and Maurice Wilkins led to the discovery of the deoxyribonucleic acid (DNA) double-helix conformation [1,2].
Fidelis Manyanga
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Nucleic Acid Binding Thermodynamics and Functions of DNA Polymerases
, 2013 ................................................................................................................................... iv CHAPTER 1. GENERAL INTRODUCTION ...............................................................................1 1.1 ...
Hiromi Brown
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Thermodynamic Analysis of Interacting Nucleic Acid Strands [PDF]
SIAM Review, 2007 Motivated by the analysis of natural and engineered DNA and RNA systems, we present the first algorithm for calculating the partition function of an unpseudoknotted complex of multiple interacting nucleic acid strands.
Bois, Justin S. +4 more
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Expanding the Functions of KHSRP Protein: Insights into DNA G‐Quadruplex Binding [PDF]
Advanced ScienceKHSRP (KH‐type splicing regulatory protein) is a multifunctional nucleic acid‐binding protein that regulates various cellular processes, with critical roles in controlling gene expression.
Pasquale Russomanno +9 more
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What Controls the Hybridization Thermodynamics of Spherical Nucleic Acids?* [PDF]
Journal of the American Chemical Society, 2020 The hybridization of free oligonucleotides to densely packed, oriented arrays of DNA modifying the surfaces of spherical nucleic acid (SNA)-gold nanoparticle conjugates occurs with negative cooperativity; i.e., each binding event destabilizes subsequent binding events. DNA hybridization is thus an ever-changing function of the number of strands already
Pratik S. Randeria +6 more
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Editorial: Thermodynamics and structure of nucleic acids with modified bases [PDF]
Biopolymers, 2002 Luis A. Marky
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Thermodynamics of Nucleic Acid Structural Modifications for Biotechnology Applications
, 2011 The repertoire of chemistry available to native nucleotides in DNA and RNA is limited to the purine and pyrimidine functional groups, along with the special role of the 2’-hydroxyl of RNA. The nucleobases have exocyclic amino groups and imines, neither of which is highly reactive or a good candidate for catalytic function.
Stefan Franzen
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