Results 31 to 40 of about 191,094 (249)
Nucleic acid-lipid membrane interactions studied by DSC
Journal of Pharmacy and Bioallied Sciences, 2011 The interactions of nucleic acids with lipid membranes are of great importance for biological mechanisms as well as for biotechnological applications in gene delivery and drug carriers. The optimization of liposomal vectors for clinical use is absolutely
Sarantis Giatrellis, George Nounesis
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NTDB: Thermodynamic Database for Nucleic Acids, Version 2.0 [PDF]
Nucleic Acids Research, 2003 The second release of Thermodynamic Database for Nucleic Acids, NTDB 2.0, includes more than 4600 entries (250% increase over release 1.0). It contains sequence types and details of several thermodynamic parameters (enthalpy, DeltaH; entropy, DeltaS; Gibbs free energy, DeltaG; melting temperature, T(m)), experimental models and methods for extracting ...
Lai Fan Chiu +5 more
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Dynamics of Ionic Interactions at Protein–Nucleic Acid Interfaces
Accounts of Chemical Research, 2020 Conspectus Molecular association of proteins with nucleic acids is required for many biological processes essential to life. Electrostatic interactions via ion pairs (salt bridges) of nucleic acid phosphates and protein side chains are crucial for ...
Binhan Yu, B. Pettitt, J. Iwahara
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BioTechniques, 2008 A rapid capture technique was developed to efficiently isolate specific DNA targets from a variety of genomes. The specificity can be easily adapted to any target for which partial sequence is known, allowing for the isolation of a wide set of target ...
Judy St. John, Thomas W. Quinn
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Studying epigenetic interactions using MicroScale Thermophoresis (MST)
AIMS Biophysics, 2015 Epigenetic regulation is based on specific molecular interactions between epigenetic reader, writer and eraser molecules and chromatin. Binding parameters of these interactions such as binding affinities, stoichiometries and thermodynamics are essential ...
Thomas Schubert, Gernot Längst
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An efficient algorithm for the stochastic simulation of the hybridization of DNA to microarrays
BMC Bioinformatics, 2009 Background Although oligonucleotide microarray technology is ubiquitous in genomic research, reproducibility and standardization of expression measurements still concern many researchers. Cross-hybridization between microarray probes and non-target ssDNA
Laurenzi Ian J, Arslan Erdem
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BMC Bioinformatics, 2007 Background RNA interference (RNAi) is a naturally occurring phenomenon that results in the suppression of a target RNA sequence utilizing a variety of possible methods and pathways.
Peek Andrew S
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Modified RNA triplexes: Thermodynamics, structure and biological potential
Scientific Reports, 2018 The occurrence of triplexes in vivo has been well documented and is determined by the presence of long homopurine-homopyrimidine tracts. The formation of these structures is the result of conformational changes that occur in the duplex, which allow the ...
Marta Szabat +2 more
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ProTherm and ProNIT: thermodynamic databases for proteins and protein-nucleic acid interactions [PDF]
Nucleic Acids Research, 2006 ProTherm and ProNIT are two thermodynamic databases that contain experimentally determined thermodynamic parameters of protein stability and protein-nucleic acid interactions, respectively. The current versions of both the databases have considerably increased the total number of entries and enhanced search interface with added new fields, improved ...
K. Abdulla Bava +6 more
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Journal of Physical Chemistry B, 2018 Amino acid and nucleic acid interactions are central in biology and may have played a role in the evolutionary development of protein-based life from an early "RNA Universe." To explore the possible role of single amino acids in promoting nucleic acid ...
D. Nicholson +3 more
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