Results 61 to 70 of about 191,094 (249)

DNA Sequential Logic Circuits for Reversible Counters and Dynamic Biomolecular Sensing

Advanced Science, EarlyView.
In this work, a DNA sequential logic circuit is constructed that combines reusability and autonomy for the first time, including SR (Set‐Reset)‐latches composed of NOR gates, SR‐latches composed of NAND gates, and D (Data)‐latches. After fully utilizing the characteristics of each latch, to counter, toxin and miRNA detection and intracellular dynamic ...
Tianci Xie, Changjiang Li, Minghao Hu, Xingyu Zhong, Junbin Xiao, Zhen Zhang, Ze Wang, Tongbo Wu   +7 more
wiley   +1 more source

Rapid and Ultra‐Sensitive SARS‐CoV‐2 Subgenomic RNA Detection Using Single‐Molecule With a Large Transistor‐SiMoT Bioelectronic Platform

Advanced Electronic Materials, EarlyView.
The single‐molecule with a large transistor‐SiMoT is proposed for the detection of the subgenomic RNA of SARS‐CoV‐2, achieving a diagnostic sensitivity of 98.0% and a specificity of 87.8%. The SiMoT technology, currently at TRL‐5, is suitable for point‐of‐care settings and delivers the result to the end user in 30 min.
Eleonora Macchia, Anna Maria D'Erchia, Mariapia Caputo, Angelica Bianco, Claudia Leoni, Francesca Intranuovo, Cecilia Scandurra, Lucia Sarcina, Cinzia Di Franco, Paolo Bollella, Gaetano Scamarcio, Luisa Torsi, Graziano Pesole   +12 more
wiley   +1 more source

Applied Artificial Intelligence in Materials Science and Material Design

Advanced Intelligent Systems, EarlyView.
AI‐driven methods are transforming materials science by accelerating material discovery, design, and analysis, leveraging large datasets to enhance predictive modeling and streamline experimental techniques. This review highlights advancements in AI applications across spectroscopy, microscopy, and molecular design, enabling efficient material ...
Emigdio Chávez‐Angel, Martin Børstad Eriksen, Alejandro Castro‐Alvarez, Jose H. Garcia, Marc Botifoll, Oscar Avalos‐Ovando, Jordi Arbiol, Aitor Mugarza   +7 more
wiley   +1 more source

The Limitation of the Combination of Transition State Theory and Thermodynamics for the Reactions of Proteins and Nucleic Acids [PDF]

, 2021
Nobuo Shimamoto
openalex   +1 more source

Design of nucleic acid sequences for DNA computing based on a thermodynamic approach

Nucleic Acids Research, 2005
We have developed an algorithm for designing multiple sequences of nucleic acids that have a uniform melting temperature between the sequence and its complement and that do not hybridize non-specifically with each other based on the minimum free energy (DeltaG (min)).
Tanaka, Fumiaki, Kameda, Atsushi, Yamamoto, Masahito, Ohuchi, Azuma   +3 more
openaire   +4 more sources

Red‐Light‐Mediated Generation of Radicals: Applications in Organic Synthesis, Small‐Molecule Activation, Polymerization, and Bio‐Related Fields

Angewandte Chemie International Edition, Accepted Article.
The field of visible light‐mediated photochemistry has experienced significant growth, leading to the development of a wide array of methodologies in synthetic organic chemistry. In particular, photocatalysis by using long‐wavelength light such as red and near‐infrared (NIR) light has garnered substantial attention recently.
Tong Zhang, Suman Pradhan, Shoubhik Das
wiley   +1 more source

Complex Donuts: Small Variations in DNA Sequence Dictate Pathway Complexity in DNA Nanotoroids

Angewandte Chemie International Edition, Accepted Article.
The formation of higher‐order structures in natural biopolymers like polypeptides and nucleic acids is governed by sequence specificity and monomer chemistry. Nucleic acids can assemble into programmable nanostructures through base‐pairing interactions, but their chemical diversity is limited to four nucleobases.
Muhammad Ghufran Rafique, Yihao Wu, Yutong Shi, Quentin Laurent, Abdelrahman Elmanzalawy, Yu Shi, Dmytro F. Perepichka, Jianing Li, Hanadi Farouk Sleiman   +8 more
wiley   +1 more source

Protonated Glutamate and Aspartate Side Chains Can Recognize Phosphodiester Groups via Strong and Short Hydrogen Bonds in Biomacromolecular Complexes

Angewandte Chemie International Edition, EarlyView.
The highly negatively charged phosphodiester groups of nucleic acids and cyclic (di‐)nucleotides often interact with amino acids containing polar or positively charged sidechains. Due to charge repulsion with their negatively charged carboxylate groups in their side chains, glutamate and aspartate are considered to be detrimental to such interactions ...
Konstantin Neißner, Elke Duchardt‐Ferner, Christoph Wiedemann, Julian Kraus, Ute A. Hellmich, Jens Wöhnert   +5 more
wiley   +1 more source

An Update: Enzymatic Synthesis for Industrial Applications

Angewandte Chemie International Edition, EarlyView.
Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe T. Bornscheuer   +4 more
wiley   +1 more source

Contributions of the Histidine Side Chain and the N-Terminal α-Amino Group to the Binding Thermodynamics of Oligopeptides to Nucleic Acids as a Function of pH [PDF]

, 2010
Jeff D. Ballin, James P. Prevas, Christina Ross, Eric A. Toth, Gerald M. Wilson, M. Thomas Record   +5 more
openalex   +1 more source