Results 61 to 70 of about 55,484 (212)
Applied Artificial Intelligence in Materials Science and Material Design
Advanced Intelligent Systems, EarlyView.AI‐driven methods are transforming materials science by accelerating material discovery, design, and analysis, leveraging large datasets to enhance predictive modeling and streamline experimental techniques. This review highlights advancements in AI applications across spectroscopy, microscopy, and molecular design, enabling efficient material ...
Emigdio Chávez‐Angel +7 more
wiley +1 more source
Chemical Biology &Drug Design, Volume 101, Issue 2, Page 340-349, February 2023., 2023 Non‐cytotoxic C2‐linked alkynyl oligo ethylene glycol adenosine conjugates are highly water soluble and stimulate adenosine receptor activity. Abstract A series of 12 novel polyethylene‐glycol(PEG)‐alkynyl C2‐adenosine(ADN) conjugates were synthesized using a robust Sonogashira coupling protocol and characterized by NMR spectroscopy and mass ...
Lindsay Ferguson +8 more
wiley +1 more source
MicroRNA‐205‐5p: A potential therapeutic target for influenza A
Journal of Cellular and Molecular Medicine, Volume 26, Issue 23, Page 5917-5928, December 2022., 2022 Abstract We are committed to finding host targets for influenza A therapeutics. The nucleoprotein (NP) plays an important role in influenza A virus replication and is an indispensable part of viral transcription and replication. Exploring endogenous substances that can modulate NP is critical for finding host targets.
Yanyan Bao +9 more
wiley +1 more source
A new formalism for calculation of the partition function of single stranded nucleic acids [PDF]
arXiv, 2005 A new formalism for calculation of the partition function of single stranded nucleic acids is presented. Secondary structures and the topology of structure elements are the level of resolution that is used. The folding model deals with matches, mismatches, symmetric and asymmetric interior loops, stacked pairs in loop and dangling end regions, multi ...
arxiv
An Update: Enzymatic Synthesis for Industrial Applications
Angewandte Chemie International Edition, Accepted Article.Supported by rapid technological advancements, biocatalytic applications have matured into a sustainable, scalable, and cost‐competitive alternatives to established chemical catalysis. This review presents the most recent examples of enzyme‐based solutions for the manufacturing of molecules with extended carbon‐carbon frameworks and multiple ...
Thomas Bayer +4 more
wiley +1 more source
The Limitation of the Combination of Transition State Theory and Thermodynamics for the Reactions of Proteins and Nucleic Acids [PDF]
, 2021 Nobuo Shimamoto
openalex +1 more source
pH‐Directed Capture‐SELEX for Nanomolar Affinity Aptamers for Kanamycin Detection
Analysis &Sensing, EarlyView.Considering the four pKa values of kanamycin A being all close to 7, two parallel SELEX experiments were carried out at pH 6 and 8. The pH 6 selection yielded a kanamycin aptamer with nanomolar affinity, which was used for fluorescent biosensor development.
Yichen Zhao, Juewen Liu
wiley +1 more source
Bioelectronics with Topological Crosslinked Networks for Tactile Perception
Advanced Physics Research, EarlyView.The recent advances in 3 different topological crosslinked networks are summarized, focusing on their assembly methods, structural characteristics, and device performance decoupling. Also, the ionic and electronic transport mechanisms, which provide insights into ionic‐electronic coupling, are elaborated.
Mingqi Ding, Pengshan Xie, Johnny C. Ho
wiley +1 more source
What Controls the Hybridization Thermodynamics of Spherical Nucleic Acids?* [PDF]
, 2020 Pratik S. Randeria +6 more
openalex +2 more sources
Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application
BMEMat, EarlyView.The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah +9 more
wiley +1 more source