Primordial RNA Replication and Applications in PCR Technology [PDF]
The emergence of self-replication and information transmission in life's origin remains unexplained despite extensive research on the topic. A hypothesis explaining the transition from a simple organic world to a complex RNA world is offered here based ...
Palasek, Stan
core
Thermodynamics of Nucleic Acid Structural Modifications for Biotechnology Applications
The repertoire of chemistry available to native nucleotides in DNA and RNA is limited to the purine and pyrimidine functional groups, along with the special role of the 2’-hydroxyl of RNA. The nucleobases have exocyclic amino groups and imines, neither of which is highly reactive or a good candidate for catalytic function.
openaire +3 more sources
ASOG: AntiSense Oligonucleotide Generator. [PDF]
Kimi J +6 more
europepmc +1 more source
3PA120 Thermodynamic Database for Protein-Nucleic Acid Interactions
P. Prabakaran +5 more
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Theoretical Modeling of the Redox Thermodynamics of Nucleic Acid Building Blocks in the Condensed Phase. [PDF]
Olivieri A, Nardi AN, D'Abramo M.
europepmc +1 more source
Molecular Dissipative Structuring: The Fundamental Creative Force in Biology. [PDF]
Michaelian K.
europepmc +1 more source
Multimodal investigation of dacomitinib-calf thymus DNA binding interaction: insights from spectroscopy, thermodynamics, and in-silico studies. [PDF]
Alossaimi MA +4 more
europepmc +1 more source
Cadaverine modulates bovine alkaline phosphatase kinetics and structure: spectroscopic and bioinformatics study. [PDF]
Babaknejad N +3 more
europepmc +1 more source
ThermoPlex: an automated design tool for target-specific multiplex PCR primers based on DNA thermodynamics. [PDF]
Agmata A +3 more
europepmc +1 more source
Nucleic acid base pair open states by hydrogen exchange. [PDF]
Englander SW.
europepmc +1 more source

