Results 61 to 70 of about 34,544 (276)

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

Advanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding, Bing Liu, Andreas Peil, Sisi Fan, Jie Chao, Na Liu   +5 more
wiley   +1 more source

Expanding the Functions of KHSRP Protein: Insights into DNA G‐Quadruplex Binding

Advanced Science
KHSRP (KH‐type splicing regulatory protein) is a multifunctional nucleic acid‐binding protein that regulates various cellular processes, with critical roles in controlling gene expression.
Pasquale Russomanno, Pasquale Zizza, Linda Cerofolini, Federica D'Aria, Sara Iachettini, Serena Di Vito, Annamaria Biroccio, Jussara Amato, Marco Fragai, Bruno Pagano   +9 more
doaj   +1 more source

Mussel‐Inspired Molecular Strategies for Fabricating Functional Materials With Underwater Adhesion and Self‐Healing Properties

Advanced Materials, EarlyView.
This review systematically examines the nanomechanical mechanisms of mussel‐inspired molecular interactions, primarily investigated by direct force measurement techniques such as surface forces apparatus and atomic force microscopy. The macroscopic adhesive and self‐healing performances of mussel‐inspired functional materials, including coacervates ...
Pan Huang, Hongjian Zhang, Hongbo Zeng
wiley   +1 more source

Engineered Plasmonic and Fluorescent Nanomaterials for Biosensing, Motion, Imaging, and Therapeutic Applications

Advanced Materials, EarlyView.
A schematic illustration of how noble metals can be used to create nanoparticles (NPs) or nanoclusters (NCs). Noble metal NPs, due to their plasmonic properties, enable photothermal therapy and surface‐enhanced Raman scattering (SERS). In contrast, NCs, which lack a plasmonic resonance band, exhibit fluorescence, making them ideal for bioimaging ...
David Esporrín‐Ubieto, Juan C. Fraire, Daniel Sánchez‐deAlcázar, Samuel Sánchez   +3 more
wiley   +1 more source

Universal Method for Covalent Attachment of Hydrogels to Diverse Polymeric Surfaces for Biomedical Applications

Advanced Materials, EarlyView.
A universal, reagent‐free strategy is presented for covalently attaching hydrogels to diverse polymeric substrates through reactive oxygen species. The scalable, linker‐free approach enables robust adhesion and broad material compatibility, advancing the fabrication of hybrid solid–hydrogel systems for next‐generation biomedical devices and bioprinting
Masoud Zhianmanesh, Azin Khodaei, Matthew Crago, Oliver Lotz, Sina Naficy, Fariba Dehghani, Marcela Bilek, Saber Amin Yavari, Behnam Akhavan   +8 more
wiley   +1 more source

Mechanistic studies on DNA damage by minor groove binding copper–phenanthroline conjugates [PDF]

, 2005
Copper–phenanthroline complexes oxidatively damage and cleave nucleic acids. Copper bis-phenanthroline and copper complexes of mono- and bis-phenanthroline conjugates are used as research tools for studying nucleic acid structure and binding interactions.
Bales, Brian C., Greenberg, Marc M., Kodama, Tetsuya, Meunier, Bernard, Pitié, Marguerite, Weledji, Yvonne N.   +5 more
core   +2 more sources

Nanostructured Protein Surfaces Inspired by Spider Silk

Advanced Materials, EarlyView.
Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley   +1 more source

Tailoring Advanced Metal‐Based Nanomedicines for Adaptable Nanodynamic Disease Therapies and Theranostics

Advanced Materials, EarlyView.
This review summarizes recent advances in metal‐based nanomaterials (MBNs) as multifunctional platforms for next‐generation diagnostics and nanodynamic therapies (NDTs), highlighting their structural tunability, diverse therapeutic modalities, and broad biomedical applications in oncology and infectious disease control.
Qihang Ding, Wenhao Li, Ling Mei, Suling Luo, Jing Tao, Chongxiu Shi, Hongping Yang, Wei Feng, Yungchang Chen, Yu Chen, Jong Seung Kim, Xue Shen   +11 more
wiley   +1 more source

Encapsulation of a polymer by an icosahedral virus

, 2010
The coat proteins of many viruses spontaneously form icosahedral capsids around nucleic acids or other polymers. Elucidating the role of the packaged polymer in capsid formation could promote biomedical efforts to block viral replication and enable use ...
Elrad, Oren M., Hagan, Michael F.
core   +1 more source

Antibody‐Functionalized DNA Hydrogels Recognize and Isolate Living Tumor Cells

Advanced Materials Interfaces, EarlyView.
We present a novel strategy using DNA Y‐motif nanostar hydrogels and DNA‐functionalized antibodies for precise live‐cell manipulation. Target cells are labeled with DNA sticky ends that hybridize with DNA Y‐motifs, enabling their incorporation and capture within the hydrogel during self‐assembly.
Laura Bourdon, Audrey Cochard, Yannick Tauran, Yoshinobu Sugitani, Yusuke Sato, Masahiro Takinoue, Hiroyuki Fujita, Teruo Fujii, Soo Hyeon Kim, Anthony J. Genot   +9 more
wiley   +1 more source