Results 61 to 70 of about 34,496 (157)

Primordial RNA Replication and Applications in PCR Technology [PDF]

open access: yes, 2013
The emergence of self-replication and information transmission in life's origin remains unexplained despite extensive research on the topic. A hypothesis explaining the transition from a simple organic world to a complex RNA world is offered here based ...
Palasek, Stan
core  

Thermodynamics of Nucleic Acid Structural Modifications for Biotechnology Applications

open access: yes, 2011
The repertoire of chemistry available to native nucleotides in DNA and RNA is limited to the purine and pyrimidine functional groups, along with the special role of the 2’-hydroxyl of RNA. The nucleobases have exocyclic amino groups and imines, neither of which is highly reactive or a good candidate for catalytic function.
openaire   +3 more sources

ASOG: AntiSense Oligonucleotide Generator. [PDF]

open access: yesComput Struct Biotechnol J
Kimi J   +6 more
europepmc   +1 more source

3PA120 Thermodynamic Database for Protein-Nucleic Acid Interactions

open access: yesSeibutsu Butsuri, 1999
P. Prabakaran   +5 more
openaire   +1 more source

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