Results 81 to 90 of about 192,096 (245)

Artificial intelligence‐assisted design, synthesis and analysis of smart biomaterials

open access: yesBMEMat, EarlyView.
Smart biomaterials are rapidly emerging as tools for tissue engineering, and artificial intelligence has played essential roles in biomaterial studies. By bridging the literature gap in AI‐based design, synthesis and analysis of smart biomaterials, the current review shares perspectives on how biomaterial scientists can practically incorporate AI for ...
Pengfei Jiang   +9 more
wiley   +1 more source

New Trends in SERS Substrates With Micro‐ and Nanostructures: Materials, Substrates, Preparation, and Applications

open access: yesBattery Energy, EarlyView.
In this review, the latest research progress in surface‐enhanced Raman scattering (SERS) is discussed comprehensively. It covers four main aspects of SERS technology: materials utilized, various types of SERS substrates, methods employed for their preparation, and recent applications explored in the field over the past few years.
Xiaoyu Tian   +7 more
wiley   +1 more source

Robotic‐Assisted Capture‐Systematic Evolution of Ligands by Exponential Enrichment of RNA Aptamers Binding to Small Molecules

open access: yesChemBioChem, EarlyView.
This study demonstrates the rapid selection of RNA aptamers that can target various small molecules through a newly established automated capture‐systematic evolution of ligands by exponential enrichment technique. Throughout the study, this method is applied to aptamer selection for several small molecules, resulting in aptamers that bind with high ...
Tjasa Legen, Günter Mayer
wiley   +1 more source

Designs and Materials of Electrodes for Electrochemical Sensors

open access: yesChemElectroChem, EarlyView.
Nowadays, electrochemical sensors and biosensors play a crucial role in modern life. This work highlights the importance of electrode material selection and chip design in optimizing sensor performance. It provides a practical guide for choosing suitable materials and structural configurations tailored to specific sensing applications, aiming to ...
Pierre J. Obeid   +8 more
wiley   +1 more source

The Azidofunctionalization of Alkenes

open access: yesChemistryEurope, EarlyView.
The azidofunctionalization of alkenes offers a powerful strategy for synthesizing nitrogen‐containing compounds by installing both an azide and a second functional group in one step. This approach, employing photoredox catalysis, transition metals, and radical methods, is efficient, selective, and versatile, with applications in pharmaceuticals and ...
Pierre Palamini, Jerome Waser
wiley   +1 more source

Mellitic Acid as a Stable Abiotic Precursor for Liquid‐Liquid Phase Separation: An RNA‐Independent Pathway for Prebiotic Compartmentalization

open access: yesChemistry – A European Journal, EarlyView.
Evidence is presented that prebiotically accessible mellitic (benzenehexacarboxylic) acid (MAc) is forming liquid droplets with short poly‐L‐lysine. The capacity of MAc to induce liquid‐liquid phase separation with short oligocations, along with abiotic synthesis routes, makes MAc a viable candidate for an ingredient of early prebiotic membraneless ...
Robert Dec   +4 more
wiley   +1 more source

Efficacy of DNA Intercalator‐Conjugated Triplex‐Forming Oligonucleotide as Anticancer Agent

open access: yesChemMedChem, Accepted Article.
A triplex‐forming oligonucleotide (TFO) can form a sequence‐specific triple helix via Hoogsteen hydrogen bonding to polypurine tracts within a major groove side of a DNA duplex. Triplex formation can induce a double‐strand break, and this phenomenon at the amplified gene loci can selectively induce the cell death of cancer cells with specific gene ...
Haruki Toyama   +5 more
wiley   +1 more source

Capillary Electrophoresis Can Detect the Simultaneous Presence of Hairpins and Self‐Dimers in Non‐Symmetric, Single‐Stranded DNA Oligomers

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT Free solution capillary electrophoresis (CE) has been used to show that non‐symmetric, single‐stranded DNA oligomers containing 26 nucleotides can exhibit peaks in the electropherograms that correspond to the simultaneous presence of self‐dimers and hairpins in the solution.
Earle Stellwagen, Nancy C. Stellwagen
wiley   +1 more source

Recent advances in isothermal amplification techniques coupled with clustered regularly interspaced short palindromic repeat/Cas systems

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract Isothermal amplification (IA) techniques have emerged as promising alternatives to polymerase chain reaction (PCR), enabling rapid and efficient nucleic acid amplification at constant temperatures. Meanwhile, clustered regularly interspaced short palindromic repeat (CRISPR)/Cas‐based technology has revolutionized molecular diagnostics by ...
Miao Liu   +7 more
wiley   +1 more source

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