Results 221 to 230 of about 1,094,037 (343)

Corrigendum to “Development of traceable international standard materials using sequence-customized lentivirus, modeled on SARS-CoV-2 nucleic acid amplification tests, and validation through a pilot external quality assessment” [J Infect Chemother 31 (5) 2025 102694] [PDF]

Kotaro Aoki, Yoshikazu Ishii
openalex   +1 more source

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

An Aqueous-Compatible On-Column Approach for the Conjugation of Nucleic Acids Using Amino Modifiers. [PDF]

Curr Protoc
Saraya JS, O'Flaherty DK.
europepmc   +1 more source

Automation of Silica Bead-based Nucleic Acid Extraction on a Centrifugal Lab-on-a-Disc Platform [PDF]

, 2016
David J. Kinahan, Faith Mangwanya, Robert Garvey, Danielle Chung, A. Lipiński, Lourdes Albina Nirupa Julius, Damien King, Mehdi Mohammadi, Rohit Mishra, May Al-Ofi, Celina M. Miyazaki, Jens Ducrée   +11 more
openalex   +1 more source

Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery

Advanced Healthcare Materials, EarlyView.
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han, Donghyun Kim, Haram Lee, Dong‐Wook Park, Sung Soo Kwak, Joohee Kim   +5 more
wiley   +1 more source

Rapid Synthesis and Diversification of Thymine-Containing Bridged Nucleic Acids Through Cascade Cyclization Reactions. [PDF]

Angew Chem Int Ed Engl
Huxley C, Fung E, Singh B, Caballero-García G, Muir G, Silverman SM, Campeau LC, Britton R.   +7 more
europepmc   +1 more source

A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids

Advanced Healthcare Materials, EarlyView.
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova, Fatemeh Ahmadi, Jennifer Cruickshank, Zheyuan Miao, David W. Cescon, Eugenia Kumacheva   +5 more
wiley   +1 more source

Magnetic activation of spherical nucleic acids enables the remote control of synthetic cells. [PDF]

Nat Chem
Parkes E, Al Samad A, Mazzotti G, Newell C, Ng B, Radford A, Booth MJ.   +6 more
europepmc   +1 more source

Role of Electron Spin, Chirality, and Charge Dynamics in Promoting the Persistence of Nascent Nucleic Acid–Peptide Complexes

Pratik Vyas, Kakali Santra, Naupada Preeyanka, Anu Gupta, Orit Weil‐Ktorza, Qirong Zhu, Norman Metanis, Jonas Fransson, Liam M. Longo, Ron Naaman   +9 more
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Real-Time Nucleic Acid Sequence-Based Amplification Is More Convenient than Real-Time PCR for Quantification of Plasmodium falciparum

, 2005
Petra Schneider, Liselotte Wolters, Gerard J. Schoone, Henk D. F. H. Schallig, Peter Sillekens, Rob Hermsen, Robert W. Sauerwein   +6 more
openalex   +2 more sources