Results 221 to 230 of about 1,078,683 (343)

Synergistic Upregulation of Extracellular Vesicles and Cell-Free Nucleic Acids by Chloroquine and Temozolomide in Glioma Cell Cultures. [PDF]

Int J Mol Sci
Aleksandrov AE, Bankov BI, Djeliova VL, Antov GG, Stoichev S, Mironova RS, Iliev DB.   +6 more
europepmc   +1 more source

Hormones and liver cytoplasm. 5. Enzymes concerned in nucleic-acid catabolism, as affected by hypophysectomy or adrenalectomy [PDF]

, 1958
E. Emmet Reid, Barbara M. Stevens
openalex   +1 more source

Molecular Simulations of Polymer‐based Drug Nanocarriers: From Physical and Structural Properties to Controlled Release

Advanced Healthcare Materials, EarlyView.
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao, Xin Jiang, Jinyu Li, Julien Nicolas, Tâp Ha‐Duong   +4 more
wiley   +1 more source

Targeting intestinal inflammation using locked nucleic acids delivered via lipid nanoparticles. [PDF]

Nat Commun
Qassem S, Naidu GS, Goldsmith M, Breier D, Rampado R, Ramishetti S, Keller M, Schumacher F, Lassen KG, Otikovs L, Kamyshinsky R, Hazan-Halevy I, Peer D.   +12 more
europepmc   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

CRISPR/Cas12a-Chemiluminescence Cascaded Bioassay for Amplification-Free and Sensitive Detection of Nucleic Acids. [PDF]

Biosensors (Basel)
Guan X, Wang P, Wang Y, Sun S.
europepmc   +1 more source

NUCLEOTIDE COMPOSITION OF PENTOSE NUCLEIC ACIDS FROM YEAST AND MAMMALIAN TISSUES

, 1950
Erwin Chargaff, Boris Magasanik, E. Vischer, Charlotte Green, Ruth. Doniger, David Elson   +5 more
openalex   +1 more source

FIXATION OF C ¹⁴ O ₂ INTO NUCLEIC ACID CONSTITUENTS BY BRUCELLA ABORTUS [PDF]

, 1954
J.W. Newton, A. G. Marr, J. B. Wilson
openalex   +1 more source

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

Advanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle, Dhruv Menon, João Conniot, Jon Ostolaza‐Paraiso, Sergio Mercado, Jhenifer Oliveira, Xu Chen, Bárbara B. Mendes, João Conde, David Fairen‐Jimenez   +9 more
wiley   +1 more source

The Bacterial Component of Soybean Root Nodules; Changes in Respiratory Activity, Cell Dry Weight and Nucleic Acid Content with Increasing Nodule Age

, 1958
F. J. Bergersen
openalex   +1 more source