Results 271 to 280 of about 1,103,498 (342)

The current situation and the future outlook of the development of nucleic acid/gene medicines from the industrial viewpoint: The relevance to DDS

, 2019
Hiroshi Kikuchi
openalex   +2 more sources

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

Targeting intestinal inflammation using locked nucleic acids delivered via lipid nanoparticles. [PDF]

Nat Commun
Qassem S, Naidu GS, Goldsmith M, Breier D, Rampado R, Ramishetti S, Keller M, Schumacher F, Lassen KG, Otikovs L, Kamyshinsky R, Hazan-Halevy I, Peer D.   +12 more
europepmc   +1 more source

Rapid Discrimination of African Swine Fever Virus Nucleic Acid and Virions Using Nuclease

Cuiying Kong, Xueying Fu, Wenbo Zhang, Yi Luo, Zhanzhuo Mai, Zhao Huang, Guihong Zhang, Pei Zhou   +7 more
openalex   +1 more source

Studies on the Decomposition of Nucleic Acid by Microörganisms

, 1955
Akira Kuninaka
openalex   +2 more sources

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

Highly Active and Stable Au@Pt Nanozymes-Based Colorimetric Nucleic Acids Detection for Varicella-Zoster Virus Diagnosis. [PDF]

Int J Nanomedicine
Zong M, Liu F, Long L, Liu J, Wu X.
europepmc   +1 more source

Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation

Advanced Science, EarlyView.
BPB (Bisphenol B) exposure up‐regulates ER (estrogen receptor) levels, enhances its interactions with the lnc‐HZ04 promoter region, and thus promotes ER‐mediated lnc‐HZ04 transcription. Subsequently, lnc‐HZ04 suppresses TCF4 (transcription factor 4)‐mediated PKCA (protein kinase C alpha) transcription and subsequently suppresses migration/invasion and ...
Wenxin Huang, Manli Wang, Yi Sun, Xiaoping Yue, Xun Li, Yanbing Lin, Geng Guo, Depeng Zhao, Qigang Fan, Xiaoling Ma, Zhihong Zhang, Shuaishuai Xing, Xiaoting Shen, Huidong Zhang   +13 more
wiley   +1 more source

Photochemical Stabilization of Self-Assembled Spherical Nucleic Acids. [PDF]

Small
Kaviani S, Bai H, Das T, Asohan J, Elmanzalawy A, Marlyn J, Choueiri LE, Damha MJ, Laurent Q, Sleiman HF.   +9 more
europepmc   +1 more source