Results 271 to 280 of about 6,062,195 (387)

Mass‐Manufactured Gradient Plasmonic Metasurfaces for Enhanced Mid‐IR Spectrochemical Analysis of Complex Biofluids

Advanced Materials, EarlyView.
This article presents a surface‐enhanced infrared absorption spectroscopy (SEIRAS) platform using mass‐manufactured gradient plasmonic metasurfaces, overcoming limitations in analyzing real‐world biosamples. The technology achieves 20‐fold signal enhancement and demonstrates superior molecular fingerprinting capabilities.
Samir Rosas, Shovasis Kumar Biswas, Wihan Adi, Furkan Kuruoglu, Aidana Beisenova, Manish S. Patankar, Filiz Yesilkoy   +6 more
wiley   +1 more source

Circular Nucleic Acids Act as an Oncogenic MicroRNA Sponge to Inhibit Hepatocellular Carcinoma Progression. [PDF]

Biomedicines
Zhang Q, Sun P, Hu G, Yu X, Zhang W, Feng X, Yu L, Zhang P.   +7 more
europepmc   +1 more source

MUTE‐Seq: An Ultrasensitive Method for Detecting Low‐Frequency Mutations in cfDNA With Engineered Advanced‐Fidelity FnCas9

Advanced Materials, EarlyView.
An advanced‐fidelity CRISPR nuclease, FnCas9‐AF2, is rationally engineered to discriminate single‐base mismatches with unprecedented level precision. Integrated into the MUTE‐Seq workflow, FnCas9‐AF2 depletes wild‐type cell‐free DNA, thereby exposing rare tumor‐derived mutant DNA (a molecular “needle in a haystack”).
Sunghyeok Ye, Jin‐Soo Kim, Myungshin Kim, Ki‐Yeon Kim, Yoon‐Ho Won, Taegun Park, Sungjae An, Haerin Jeong, Hee‐Joon Chung, In Seon Lee, Myoung‐Hee Kang, Chan Young Kang, Mi Young Kim, Jae Ho Chung, Jeong‐An Gim, Woochang Hwang, Yonggoo Kim, Song Cheol Kim, Sungho Lee, Junho K Hur, Junseok W Hur   +20 more
wiley   +1 more source

Homology modeling of 3D structure of human chitinase-like protein CHI3L2

Open Life Sciences, 2010
Iershov Anton, Odynets Konstantin, Kornelyuk Alexander, Kavsan Vadim   +3 more
doaj   +1 more source

The Nucleic Acid Fractions of a Strain of Streptococcus faecalis

, 1953
H. S. A. Sherratt, Alan Thomas
openalex   +1 more source

Bringing Attomolar Detection to the Point‐of‐Care with Nanopatterned DNA Origami Nanoantennas

Advanced Materials, EarlyView.
Single DNA molecules are captured within the hotspots of DNA origami NanoAntennas arranged on a chip surface. Fluorescence is amplified, enabling direct detection on a point‐of‐care‐compatible imaging setup (visualized as bright signals against a dark background).
Renukka Yaadav, Kateryna Trofymchuk, Mihir Dass, Vivien Behrendt, Benedikt Hauer, Jan Schütz, Cindy Close, Michael Scheckenbach, Giovanni Ferrari, Leoni Mäurer, Sophia Sebina, Viktorija Glembockyte, Tim Liedl, Philip Tinnefeld   +13 more
wiley   +1 more source

Investigating the Interactions of Peptide Nucleic Acids with Multicomponent Peptide Hydrogels for the Advancement of Healthcare Technologies. [PDF]

Gels
Giordano S, Terracciano M, Gallo E, Diaferia C, Falanga AP, Accardo A, Franzese M, Salvatore M, Piccialli G, Borbone N, Oliviero G.   +10 more
europepmc   +1 more source

A SIMPLIFIED PROCEDURE FOR THE PREPARATION OF CYTIDYLIC ACID AND DIAMMONIUM URIDYLATE FROM YEAST NUCLEIC ACID

, 1948
Hubert S. Loring, Paul M. Roll, John G. Pierce   +2 more
openalex   +1 more source

Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas

Advanced Materials, EarlyView.
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac, Luv Patel, Nguyen Tran, Amarnath Singam, DongSoo Yun, Prasun Guha, Seungman Park, Chandrabali Bhattacharya   +7 more
wiley   +1 more source