Results 31 to 40 of about 1,094,037 (343)

Ultrashort Peptide Self-Assembly: Front-Runners to Transport Drug and Gene Cargos

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
The translational therapies to promote interaction between cell and signal come with stringent eligibility criteria. The chemically defined, hierarchically organized, and simpler yet blessed with robust intermolecular association, the peptides, are ...
Seema Gupta   +4 more
doaj   +1 more source

Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome. [PDF]

open access: yes, 2015
Aicardi-Goutières syndrome (AGS) is a severe childhood inflammatory disorder that shows clinical and genetic overlap with systemic lupus erythematosus (SLE).
Chédin, Frédéric   +4 more
core   +2 more sources

Redesigning nucleic acids [PDF]

open access: yesPure and Applied Chemistry, 1998
Abstract
S A, Benner   +31 more
openaire   +2 more sources

Use of streptavidin bound to biotinylated DNA structures as model substrates for analysis of nucleoprotein complex disruption by helicases [PDF]

open access: yes, 2016
Helicases are a subfamily of translocases that couple the directional translocation along a nucleic acid lattice to the separation of nucleic acid duplexes using the energy derived from nucleoside triphosphate hydrolysis.
Brüning, Jan-Gert   +2 more
core   +1 more source

Extracellular vesicle mimetics as delivery vehicles for oligonucleotide-based therapeutics and plasmid DNA

open access: yesFrontiers in Bioengineering and Biotechnology
IntroductionSmall membrane particles called extracellular vesicles (EVs) transport biologically active cargo between cells, providing intercellular communication.
Anastasiya Oshchepkova   +15 more
doaj   +1 more source

Fluorescent labeling of plasmid DNA and mRNA : gains and losses of current labeling strategies [PDF]

open access: yes, 2016
Live-cell imaging has provided the life sciences with insights into the cell biology and dynamics. Fluorescent labeling of target molecules proves to be indispensable in this regard. In this Review, we focus on the current fluorescent labeling strategies
Rombouts, Koen   +2 more
core   +1 more source

Nucleic acid memory [PDF]

open access: yesNature Materials, 2016
Nucleic acid memory has a retention time far exceeding electronic memory. As an alternative storage media, DNA surpasses the information density and energy of operation offered by flash memory.
Zhirnov, Victor   +4 more
openaire   +3 more sources

CCT4 promotes tunneling nanotube formation

open access: yesFEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto   +3 more
wiley   +1 more source

Two-Holder Strategy for Efficient and Selective Synthesis of Lk 1 ssDNA Catenane

open access: yesMolecules, 2018
DNA catenanes are characterized by their flexible and dynamic motions and have been regarded as one of the key players in sophisticated DNA-based molecular machines.
Qi Li   +6 more
doaj   +1 more source

Counting the ions surrounding nucleic acids. [PDF]

open access: yes, 2016
Nucleic acids are strongly negatively charged, and thus electrostatic interactions-screened by ions in solution-play an important role in governing their ability to fold and participate in biomolecular interactions.
Jacobson, David R, Saleh, Omar A
core   +1 more source

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