Results 21 to 30 of about 7,473,748 (355)
FRETmatrix: a general methodology for the simulation and analysis of FRET in nucleic acids [PDF]
, 2012 Forster resonance energy transfer (FRET) is a technique commonly used to unravel the structure and conformational changes of biomolecules being vital for all living organisms.
Kilsa, K. +12 more
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Results in Chemistry, 2020 The tandem repeat stretches of cytosine residues fold to construct intercalated motif (i-motif) structures over an acidic pH range. Several advancements have been made to understand the biological role of i-motif DNA.
Swati Chaudhary +3 more
doaj +1 more source
The isolation of nucleic acids from fixed, paraffin-embedded tissues-which methods are useful when? [PDF]
, 2007 Museums and pathology collections around the world represent an archive of genetic material to study populations and diseases. For preservation purposes, a large portion of these collections has been fixed in formalin-containing solutions, a treatment ...
Haselkorn, Tamara +35 more
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Catalytic Knockdown of miR-21 by Artificial Ribonuclease: Biological Performance in Tumor Model
Frontiers in Pharmacology, 2019 Control of the expression of oncogenic small non-coding RNAs, notably microRNAs (miRNAs), is an attractive therapeutic approach. We report a design platform for catalytic knockdown of miRNA targets with artificial, sequence-specific ribonucleases ...
Olga A. Patutina +7 more
doaj +1 more source
Nucleic Acids Research, 2016 Induction of human fibroblast cells with poly rI.rC induceG interferon mRNA which can be translated into interferon precursor in wheat germ cell free system or in XenoDus oocytes into biologically active interferon.
N. Raj
semanticscholar +1 more source
Modified nucleic acids: replication, evolution, and next-generation therapeutics
BMC Biology, 2020 Modified nucleic acids, also called xeno nucleic acids (XNAs), offer a variety of advantages for biotechnological applications and address some of the limitations of first-generation nucleic acid therapeutics.
K. Duffy +2 more
semanticscholar +1 more source
Ultrashort Peptide Self-Assembly: Front-Runners to Transport Drug and Gene Cargos
Frontiers in Bioengineering and Biotechnology, 2020 The translational therapies to promote interaction between cell and signal come with stringent eligibility criteria. The chemically defined, hierarchically organized, and simpler yet blessed with robust intermolecular association, the peptides, are ...
Seema Gupta +4 more
doaj +1 more source
Nucleic Acids Research, 2010 F.Allain, Zurich, Switzerland C.Bailly, Lille, France A. Bateman, Hinxton, UK P.B.Becker, Munich, Germany M.Belfort, Albany, NY, USA B.Berkhout, Amsterdam, The Netherlands E.H.Bresnick, Madison, WI, USA J.F.Caceres, Edinburgh, UK J.S.Carroll, Cambridge ...
D. Corey
semanticscholar +1 more source
The Nucleic Acid Database: A Resource for Nucleic Acid Science [PDF]
Acta Crystallographica Section D Biological Crystallography, 1998 The Nucleic Acid Database (NDB) distributes information about nucleic acid-containing structures. Here the information content of the database as well as the query capabilities are described. A summary of how the technology developed by this project has been used to develop other macromolecular databases is given.
H M, Berman, C, Zardecki, J, Westbrook
openaire +2 more sources
, 2016 This edited book, "Nucleic Acids - From Basic Aspects to Laboratory Tools", contains a series of chapters that highlight the development and status of the various aspects of the nucleic acids related to DNA chemistry and biology and the molecular ...
core +1 more source