Informational gene phylogenies do not support a fourth domain of life for nucleocytoplasmic large DNA viruses. [PDF]
PLoS ONE, 2011 Mimivirus is a nucleocytoplasmic large DNA virus (NCLDV) with a genome size (1.2 Mb) and coding capacity ( 1000 genes) comparable to that of some cellular organisms.
Tom A Williams +2 more
doaj +6 more sources
Phylogenetic evidence for extensive lateral acquisition of cellular genes by Nucleocytoplasmic large DNA viruses [PDF]
BMC Evolutionary Biology, 2008 Background Nucleo-Cytoplasmic Large DNA viruses (NCLDV), a diverse group that infects a wide range of eukaryotic hosts, exhibit a large heterogeneity in genome size (between 100 kb and 1.2 Mb) but have been suggested to form a monophyletic group on the ...
Chandler Mick +2 more
doaj +5 more sources
The genomes of nucleocytoplasmic large DNA viruses: viral evolution writ large. [PDF]
Microb Genom, 2021 The nucleocytoplasmic large DNA viruses (NCLDVs) are a diverse group that currently contain the largest known virions and genomes, also called giant viruses. The first giant virus was isolated and described nearly 20 years ago. Their genome sizes were larger than for any other known virus at the time and it contained a number of genes that had not been
Mönttinen HAM +3 more
europepmc +5 more sources
Covariance of Marine Nucleocytoplasmic Large DNA Viruses with Eukaryotic Plankton Communities in the Sub-Arctic Kongsfjorden Ecosystem: A Metagenomic Analysis of Marine Microbial Ecosystems. [PDF]
Microorganisms, 2023 Nucleocytoplasmic large DNA viruses (NCLDVs) infect various marine eukaryotes. However, little is known about NCLDV diversity and their relationships with eukaryotic hosts in marine environments, the elucidation of which will advance the current understanding of marine ecosystems. This study characterizes the interplay between NCLDVs and the eukaryotic
Kim KE +7 more
europepmc +4 more sources
Coral Bleaching Phenotypes Associated With Differential Abundances of Nucleocytoplasmic Large DNA Viruses [PDF]
Frontiers in Marine Science, 2020 Eukaryotic viruses and bacteriophage have been implicated in disease and bleaching in corals, but the compositional and functional diversity of these viruses in healthy and compromised hosts remains underexplored. To investigate whether viral assemblages
Adriana Messyasz +10 more
doaj +3 more sources
"Megavirales", a proposed new order for eukaryotic nucleocytoplasmic large DNA viruses. [PDF]
Arch Virol, 2013 The nucleocytoplasmic large DNA viruses (NCLDVs) comprise a monophyletic group of viruses that infect animals and diverse unicellular eukaryotes. The NCLDV group includes the families Poxviridae, Asfarviridae, Iridoviridae, Ascoviridae, Phycodnaviridae, Mimiviridae and the proposed family "Marseilleviridae".
Colson P +11 more
europepmc +6 more sources
Structure-Based Deep Mining Reveals First-Time Annotations for 46 Percent of the Dark Annotation Space of the 9,671-Member Superproteome of the Nucleocytoplasmic Large DNA Viruses. [PDF]
J Virol, 2020 We extended the known annotation space for the NCLDV by 46%, revealing high-probability structural matches for fully 45% of the 9,671 query proteins and confirming up to 98% of existing annotations per virus. The most prevalent protein families included ankyrin repeat- and MORN repeat-containing proteins, many of which included an F-box, suggesting ...
Mirzakhanyan Y, Gershon PD.
europepmc +4 more sources
Comparative Genomics of Amphibian-like Ranaviruses, Nucleocytoplasmic Large DNA Viruses of Poikilotherms. [PDF]
Evol Bioinform Online, 2015 Recent research on genome evolution of large DNA viruses has highlighted a number of incredibly dynamic processes that can facilitate rapid adaptation. The genomes of amphibian-like ranaviruses - double-stranded DNA viruses infecting amphibians, reptiles, and fish (family Iridoviridae) - were examined to assess variation in genome content and ...
Price SJ.
europepmc +7 more sources
Multisubunit DNA-Dependent RNA Polymerases from Vaccinia Virus and Other Nucleocytoplasmic Large-DNA Viruses: Impressions from the Age of Structure. [PDF]
Microbiol Mol Biol Rev, 2017 SUMMARY The past 17 years have been marked by a revolution in our understanding of cellular multisubunit DNA-dependent RNA polymerases (MSDDRPs) at the structural level. A parallel development over the past 15 years has been the emerging story of the giant viruses, which encode MSDDRPs.
Mirzakhanyan Y, Gershon PD.
europepmc +6 more sources
Identification of an L-rhamnose synthetic pathway in two nucleocytoplasmic large DNA viruses. [PDF]
J Virol, 2010 ABSTRACT Nucleocytoplasmic large DNA viruses (NCLDVs) are characterized by large genomes that often encode proteins not commonly found in viruses. Two species in this group are Acanthocystis turfacea chlorella virus 1 (ATCV-1) (family Phycodnaviridae , genus Chlorovirus
Parakkottil Chothi M +8 more
europepmc +5 more sources