Analysis of virus genomes from glacial environments reveals novel virus groups with unusual host interactions [PDF]
, 2015 Microbial communities in glacial ecosystems are diverse, active, and subjected to strong viral pressures and infection rates. In this study we analyse putative virus genomes assembled from three dsDNA viromes from cryoconite hole ecosystems of Svalbard ...
Anesio, Alexandre M B +2 more
core +5 more sources
Discovery of Viral Myosin Genes With Complex Evolutionary History Within Plankton
Frontiers in Microbiology, 2021 Nucleocytoplasmic large DNA viruses (NCLDVs) infect diverse eukaryotes and form a group of viruses with capsids encapsulating large genomes. Recent studies are increasingly revealing a spectacular array of functions encoded in their genomes, including ...
Soichiro Kijima +6 more
doaj +1 more source
Immune Receptors and Co-receptors in Antiviral Innate Immunity in Plants [PDF]
, 2017 Plants respond to pathogens using an innate immune system that is broadly divided into PTI (pathogen-associated molecular pattern- or PAMP-triggered immunity) and ETI (effector-triggered immunity).
Anésia A. Santos +4 more
core +2 more sources
HuR interacts with human immunodeficiency virus type 1 reverse transcriptase, and modulates reverse transcription in infected cells [PDF]
, 2008 Reverse transcription of the genetic material of human immunodeficiency virus type 1 (HIV-1) is a critical step in the replication cycle of this virus. This process, catalyzed by reverse transcriptase (RT), is well characterized at the biochemical level.
Julie Lemay +6 more
core +2 more sources
Near-atomic structure of a giant virus
Nature Communications, 2019 Nucleocytoplasmic large DNA viruses are a group of viruses that infect many eukaryotic hosts. Here, the authors provide a 3.5 Å resolution icosahedrally-averaged capsid structure of Paramecium bursaria chlorella virus 1 and show how 1800 minor capsid ...
Qianglin Fang +11 more
doaj +1 more source
Viral and Cellular Requirements for the Nuclear Entry of Retroviral Preintegration Nucleoprotein Complexes [PDF]
, 2013 Retroviruses integrate their reverse transcribed genomes into host cell chromosomes as an obligate step in virus replication. The nuclear envelope separates the chromosomes from the cell cytoplasm during interphase, and different retroviral groups deal ...
Engelman, Alan, Matreyek, Kenneth A.
core +2 more sources
Dynein Light Chain 1 (DYNLT1) interacts with normal and oncogenic nucleoporins [PDF]
, 2013 The chimeric oncoprotein NUP98-HOXA9 results from the t(7;11)(p15;p15) chromosomal translocation and is associated with acute myeloid leukemia. It causes aberrant gene regulation and leukemic transformation through mechanisms that are not fully ...
Sarma, Nayan J, Yaseen, Nabeel R
core +10 more sources
mBio, 2019 The nucleocytoplasmic large DNA viruses (NCLDV) of eukaryotes (proposed order, “Megavirales”) include the families Poxviridae, Asfarviridae, Iridoviridae, Ascoviridae, Phycodnaviridae, Marseilleviridae, and Mimiviridae, as well as still unclassified ...
Disa Bäckström +9 more
doaj +1 more source
RNA Nuclear Export: From Neurological Disorders to Cancer [PDF]
, 2017 The presence of a nuclear envelope, also known as nuclear membrane, defines the structural framework of all eukaryotic cells by separating the nucleus, which contains the genetic material, from the cytoplasm where the synthesis of proteins takes place ...
Hautbergue, G.M.
core +1 more source
Morphological and Genomic Features of the New Klosneuvirinae Isolate Fadolivirus IHUMI-VV54
Frontiers in Microbiology, 2021 Since the discovery of Mimivirus, viruses with large genomes encoding components of the translation machinery and other cellular processes have been described as belonging to the nucleocytoplasmic large DNA viruses. Recently, genome-resolved metagenomics
Julien Andreani +5 more
doaj +1 more source