Results 31 to 40 of about 3,301 (121)

Advantages and Limits of Metagenomic Assembly and Binning of a Giant Virus

mSystems, 2020
Giant viruses have large genomes, often within the size range of cellular organisms. This distinguishes them from most other viruses and demands additional effort for the successful recovery of their genomes from environmental sequence data.
Frederik Schulz, Julien Andreani, Rania Francis, Hadjer Boudjemaa, Jacques Yaacoub Bou Khalil, Janey Lee, Bernard La Scola, Tanja Woyke   +7 more
doaj   +3 more sources

Comparative Analysis of Transcriptional Regulation Patterns: Understanding the Gene Expression Profile in Nucleocytoviricota

Pathogens, 2021
The nucleocytoplasmic large DNA viruses (NCLDV) possess unique characteristics that have drawn the attention of the scientific community, and they are now classified in the phylum Nucleocytoviricota.
Fernanda Gil de Souza, Jônatas Santos Abrahão, Rodrigo Araújo Lima Rodrigues   +2 more
doaj   +1 more source

Eukaryotic large nucleo-cytoplasmic DNA viruses: Clusters of orthologous genes and reconstruction of viral genome evolution

Virology Journal, 2009
Background The Nucleo-Cytoplasmic Large DNA Viruses (NCLDV) comprise an apparently monophyletic class of viruses that infect a broad variety of eukaryotic hosts.
Koonin Eugene V, Raoult Didier, Wolf Yuri I, Yutin Natalya   +3 more
doaj   +1 more source

The Mimivirus L375 Nudix enzyme hydrolyzes the 5' mRNA cap.

PLoS ONE, 2021
The giant Mimivirus is a member of the nucleocytoplasmic large DNA viruses (NCLDV), a group of diverse viruses that contain double-stranded DNA (dsDNA) genomes that replicate primarily in eukaryotic hosts.
Grace Kago, Susan Parrish
doaj   +1 more source

The “Neglected Viruses” of Taihu: Abundant Transcripts for Viruses Infecting Eukaryotes and Their Potential Role in Phytoplankton Succession

Frontiers in Microbiology, 2020
Drivers of algal bloom dynamics remain poorly understood, but viruses have been implicated as important players. Research addressing bloom dynamics has generally been restricted to the virus-infection of the numerically dominant (i.e. bloom forming) taxa.
Helena L. Pound, Eric R. Gann, Xiangming Tang, Lauren E. Krausfeldt, Matthew Huff, Margaret E. Staton, David Talmy, Steven W. Wilhelm   +7 more
doaj   +1 more source

Coral-associated viral communities show high levels of diversity and host auxiliary functions [PDF]

PeerJ, 2017
Stony corals (Scleractinia) are marine invertebrates that form the foundation and framework upon which tropical reefs are built. The coral animal associates with a diverse microbiome comprised of dinoflagellate algae and other protists, bacteria, archaea,
Karen D. Weynberg, Patrick W. Laffy, Elisha M. Wood-Charlson, Dmitrij Turaev, Thomas Rattei, Nicole S. Webster, Madeleine J.H. van Oppen   +6 more
doaj   +2 more sources

Grazing on Marine Viruses and Its Biogeochemical Implications

mBio, 2023
Viruses are the most abundant biological entities in the ocean and show great diversity in terms of size, host specificity, and infection cycle. Lytic viruses induce host cell lysis to release their progeny and thereby redirect nutrients from higher to ...
Kyle M. J. Mayers, Constanze Kuhlisch, Jonelle T. R. Basso, Marius R. Saltvedt, Alison Buchan, Ruth-Anne Sandaa   +5 more
doaj   +1 more source

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

Advanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng, Wenxia Bu, Fengxu Wang, Yueyuan Jin, Rongzhu Liu, Rui Zhao, Xuehai Wang, Mengna Jiang, Jinping Shen, Xinhang Cheng, Zuming Chen, Li Zhu, Jinlong Li, Zhenzhong Ge, Shichen Miao, Haotian Xu, Xiaoyu Zhou, Dongming Wang, Xinyuan Zhao   +18 more
wiley   +1 more source

PRMT9 Aggravated Dopaminergic Neurodegeneration in Parkinson's Disease Model by Facilitating the Degradation of DUSP26 and Inducing Mitochondrial Dysfunction

Advanced Science, EarlyView.
In the pathological state of PD induced by MPP+, the upregulated PRMT9 in dopaminergic neurons translocates into mitochondrion and interacts with DUSP26 and catalyzes its arginine methylation, leading to the ubiquitin‐proteasomal degradation of DUSP26 mediated by Trim32.
Tengfei Liu, Xiaomeng Song, Xin Guo, Rui Xiao, Ru Sun, Qiuran Ji, Lu Yu, Yiquan Li, Qingyi Fu, Qidi Xue, Lingjun Kong, Lin Chen, Chengjiang Gao, Huiqing Liu   +13 more
wiley   +1 more source

Welcome to pandoraviruses at the 'Fourth TRUC’ club

Frontiers in Microbiology, 2015
Nucleocytoplasmic large DNA viruses (NCLDVs), or representatives of the proposed order Megavirales, belong to families of giant viruses that infect a broad range of eukaryotic hosts.
Vikas eSharma, Vikas eSharma, Philippe eColson, Philippe eColson, Olivier eChabrol, Patrick eScheid, Pierre ePontarotti, Didier eRaoult, Didier eRaoult   +8 more
doaj   +1 more source