Results 51 to 60 of about 8,419,461 (96)

Multiple evolutionary origins of giant viruses [version 1; referees: 4 approved]

open access: yesF1000Research, 2018
The nucleocytoplasmic large DNA viruses (NCLDVs) are a monophyletic group of diverse eukaryotic viruses that reproduce primarily in the cytoplasm of the infected cells and include the largest viruses currently known: the giant mimiviruses, pandoraviruses,
Eugene V. Koonin, Natalya Yutin
doaj   +1 more source

Identification of a Potential Entry-Fusion Complex Based on Sequence Homology of African Swine Fever and Vaccinia Virus

open access: yesViruses
African swine fever virus (ASFV) belongs to the family of Asfarviridae, part of the group of nucleocytoplasmic large DNA viruses (NCLDV). Little is known about the internalization of ASFV in the host cell and the fusion membrane events that take place at
Jesús Urquiza   +6 more
doaj   +1 more source

Antarctic Marine Viruses: A Review and Future Perspectives

open access: yesOcean-Land-Atmosphere Research
This review synthesizes recent research on how Antarctic marine viruses influence polar ecosystems, focusing on their distribution, diversity, and ecological roles.
Chuan Zhai   +4 more
doaj   +1 more source

The evolution of genome compression and genomic novelty in RNA viruses [PDF]

open access: yes, 2007
The genomes of RNA viruses are characterized by their extremely small size and extremely high mutation rates ( typically 10 kb and 10(-4)/ base/ replication cycle, respectively), traits that are thought to be causally linked.
Rambaut, Andrew   +2 more
core   +1 more source

The Origin and Evolution of Viruses as Molecular Organisms [PDF]

open access: yes, 2009
Viruses are the most abundant life forms and the repertoire of viral genes is greater than that of cellular genes. It is also evident that viruses have played a major role in driving cellular evolution, and yet, viruses are not part of mainstream biology,
Claudiu I. Bandea
core  

Molecular architecture of giant viruses infecting microbial eukaryotes (protists)

open access: yesBioTechnologia
In this review, I describe recent findings on the molecular architecture and genomic characterization of giant viruses that infect microbial eukaryotes (protists) across diverse ecosystems and ecological niches.
Anhelina Kyrychenko
doaj   +1 more source

Pithovirus sibericum, a new bona fide member of the Fourth TRUC club

open access: yesFrontiers in Microbiology, 2015
Nucleocytoplasmic large DNA viruses, or representatives of the proposed order Megavirales, include giant viruses of Acanthamoeba that were discovered over the last 12 years and are bona fide microbes.
Vikas eSharma   +7 more
doaj   +1 more source

Viral Hybrid Vectors for Somatic Integration - Are They the Better Solution? [PDF]

open access: yes, 2009
The turbulent history of clinical trials in viral gene therapy has taught us important lessons about vector design and safety issues. Much effort was spent on analyzing genotoxicity after somatic integration of therapeutic DNA into the host genome. Based
Anja Ehrhardt   +6 more
core   +1 more source

Structural Characterization of Two Large Icosahedral DNA Viruses and Their Capsid Assembly Mechanisms [PDF]

open access: yes, 2020
In the last three decades, many large DNA viruses were discovered and grouped into a loosely defined clade of Nucleocytoplasmic Large DNA Viruses (NCLDVs). NCLDVs infect a wide range of hosts from single cellular protists to large animals.
Xian, Yuejiao
core   +2 more sources

Poxvirus Host Range Genes and Virus–Host Spectrum: A Critical Review

open access: yesViruses, 2017
The Poxviridae family is comprised of double-stranded DNA viruses belonging to nucleocytoplasmic large DNA viruses (NCLDV). Among the NCLDV, poxviruses exhibit the widest known host range, which is likely observed because this viral family has been more ...
Graziele Pereira Oliveira   +4 more
doaj   +1 more source

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