The Mammalian Cell Cycle Regulates Parvovirus Nuclear Capsid Assembly. [PDF]
, 2015 It is unknown whether the mammalian cell cycle could impact the assembly of viruses maturing in the nucleus. We addressed this question using MVM, a reference member of the icosahedral ssDNA nuclear parvoviruses, which requires cell proliferation to ...
Almendral, JM +5 more
core +7 more sources
Viral and Cellular Requirements for the Nuclear Entry of Retroviral Preintegration Nucleoprotein Complexes [PDF]
, 2013 Retroviruses integrate their reverse transcribed genomes into host cell chromosomes as an obligate step in virus replication. The nuclear envelope separates the chromosomes from the cell cytoplasm during interphase, and different retroviral groups deal ...
Engelman, Alan, Matreyek, Kenneth A.
core +2 more sources
VirusesAfrican swine fever virus (ASFV) belongs to the family of Asfarviridae, part of the group of nucleocytoplasmic large DNA viruses (NCLDV). Little is known about the internalization of ASFV in the host cell and the fusion membrane events that take place at
Jesús Urquiza +6 more
doaj +1 more source
The multifunctional NS1 protein of influenza A viruses [PDF]
, 2012 The non-structural (NS1) protein of influenza A viruses is a non-essential virulence factor that has multiple accessory functions during viral infection.
Hale, Benjamin Geoffrey +3 more
core +1 more source
Antarctic Marine Viruses: A Review and Future Perspectives
Ocean-Land-Atmosphere ResearchThis review synthesizes recent research on how Antarctic marine viruses influence polar ecosystems, focusing on their distribution, diversity, and ecological roles.
Chuan Zhai +4 more
doaj +1 more source
The role of Severe Acute Respiratory Syndrome (SARS)-Coronavirus Accessory Proteins in Virus Pathogenesis [PDF]
, 2012 A respiratory disease caused by a novel coronavirus, termed the severe acute respiratory syndrome coronavirus (SARS-CoV), was first reported in China in late 2002.
Fielding, Burtram C., McBride, Ruth
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Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: Structural and mechanistic insights [PDF]
, 2013 Phosphorylation adjacent to nuclear localization signals (NLSs) is involved in the regulation of nucleocytoplasmic transport. The nuclear isoform of human dUTPase, an enzyme that is essential for genomic integrity, has been shown to be phosphorylated on ...
Adams +79 more
core +1 more source
Surveillance in eastern India (2007-2009) revealed reassortment event involving ns and PB1-F2 gene segments among co-circulating influenza a subtypes [PDF]
, 2012 Background Influenza A virus encodes for eleven proteins, of which HA, NA, NS1 and PB1-F2 have been implicated in viral pathogenicity and virulence.
Mehuli Sarkar +7 more
core +2 more sources
Expression of alternatively spliced human T-cell leukemia virus type 1 mRNAs is influenced by mitosis and by a novel cis-acting regulatory sequence [PDF]
, 2016 Human T-cell leukemia virus type 1 (HTLV-1) expression depends on the concerted action of Tax, which drives transcription of the viral genome, and Rex, which favors expression of incompletely spliced mRNAs and determines a 2-phase temporal pattern of ...
Bona, Marion K. +9 more
core +1 more source
Pithovirus sibericum, a new bona fide member of the Fourth TRUC club
Frontiers in Microbiology, 2015 Nucleocytoplasmic large DNA viruses, or representatives of the proposed order Megavirales, include giant viruses of Acanthamoeba that were discovered over the last 12 years and are bona fide microbes.
Vikas eSharma +7 more
doaj +1 more source