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Anatomy and Embryology, 1993
Nucleoli are the sites of biosynthesis of the ribosomal precursors. They contain may copies of the genes for the main rRNAs (18S- and 28 S-rRNA) in the form of tandemly arranged repeats at the chromosomal nucleolar organizer regions (NORs). They also contain the small rRNA (5S-rRNA) that is synthesized outside the nucleolus, specific nucleolar proteins,
H G, Schwarzacher, F, Wachtler
openaire +2 more sources
Nucleoli are the sites of biosynthesis of the ribosomal precursors. They contain may copies of the genes for the main rRNAs (18S- and 28 S-rRNA) in the form of tandemly arranged repeats at the chromosomal nucleolar organizer regions (NORs). They also contain the small rRNA (5S-rRNA) that is synthesized outside the nucleolus, specific nucleolar proteins,
H G, Schwarzacher, F, Wachtler
openaire +2 more sources
Annual Review of Cell and Developmental Biology, 1995
The nucleolus is the site within the eukaryotic nucleus of transcription of rDNA, of processing of the rDNA transcripts, and of the formation of pre-ribosomal particles. We review current ideas for the molecular organization of these processes. The earliest transcriptional events take place near the junction of the fibrillar centers and the dense ...
P J, Shaw, E G, Jordan
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The nucleolus is the site within the eukaryotic nucleus of transcription of rDNA, of processing of the rDNA transcripts, and of the formation of pre-ribosomal particles. We review current ideas for the molecular organization of these processes. The earliest transcriptional events take place near the junction of the fibrillar centers and the dense ...
P J, Shaw, E G, Jordan
openaire +2 more sources
Nature Reviews Molecular Cell Biology, 2007
The nucleolus is a distinct subnuclear compartment that was first observed more than 200 years ago. Nucleoli assemble around the tandemly repeated ribosomal DNA gene clusters and 28S, 18S and 5.8S ribosomal RNAs (rRNAs) are transcribed as a single precursor, which is processed and assembled with the 5S rRNA into ribosome subunits.
Francois-Michel Boisvert, Angus I Lamond
exaly +4 more sources
The nucleolus is a distinct subnuclear compartment that was first observed more than 200 years ago. Nucleoli assemble around the tandemly repeated ribosomal DNA gene clusters and 28S, 18S and 5.8S ribosomal RNAs (rRNAs) are transcribed as a single precursor, which is processed and assembled with the 5S rRNA into ribosome subunits.
Francois-Michel Boisvert, Angus I Lamond
exaly +4 more sources
Annals of the New York Academy of Sciences, 2002
Abstract: The nucleolus represents a highly dynamic nuclear compartment of the interphase nucleus. It plays a key role in ribosome biogenesis. The number of nucleoli, their size, and their activity increase in exponentially growing cells; therefore these parameters reflect the proliferating activity of the cells.
M, Horký +3 more
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Abstract: The nucleolus represents a highly dynamic nuclear compartment of the interphase nucleus. It plays a key role in ribosome biogenesis. The number of nucleoli, their size, and their activity increase in exponentially growing cells; therefore these parameters reflect the proliferating activity of the cells.
M, Horký +3 more
openaire +2 more sources