Results 101 to 110 of about 48,033 (274)
Enzymatic peptide synthesis - simulation of nucleophile excess
, 1999 Gradual addition of the acyl component in small doses to a solution of the nucleophile and enzyme resulted in the yield improvement of protease-catalyzed peptide ...
Klein, Jens Uwe
core
Angewandte Chemie, EarlyView.Hydride addition to coinage‐metal diphosphine–borane complexes gives unprecedented Cu(I), Ag(I), and Au(I) hydridoborates featuring agostic σ(B–H)→M interactions. While, Cu and Ag derivatives are inert toward CO2, the Au analogue reversibly fixes CO2 and catalyzes its hydroboration as well as formic acid dehydrogenation through a cooperative B─H─Au ...
Balakrishna Peddi +4 more
wiley +2 more sources
Current Research in Structural BiologySGNH hydrolase-like fold proteins are serine proteases with the default Asp-His-Ser catalytic triad. Here, we show that these proteins share two unique conserved structural organizations around the active site: (1) the Nuc-Oxy Zone around the catalytic ...
Konstantin Denessiouk +5 more
doaj +1 more source
, 2016 Palladium-Catalyzed Nucleophile−Alkyne−α,β-Unsaturated Carbonyl Coupling through Tandem Nucleopalladation and Conjugate ...
Xiyan Lu (1470865), Zhong Wang (132073)
core +1 more source
, 2014 Citation: 'nucleophile' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.N04249 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
, 2016 Intramolecular, Nucleophile-Catalyzed Aldol-Lactonization (NCAL) Reactions: Catalytic, Asymmetric Synthesis of Bicyclic β ...
Daniel Romo (246583) +2 more
core +1 more source
Polyproline: A Synthetic Polypeptide With Unique Properties
Angewandte Chemie, EarlyView.Poly‐L‐proline is a unique polypeptide distinguished by its well‐defined secondary structures and unusual thermal behavior. This mini review highlights recent advances in the synthesis of poly‐L‐proline by N‐carboxyanhydride (NCA) polymerization, the formation of structurally defined architectures and nanostructures, and emerging strategies that ...
Rosanna Le Scouarnec +3 more
wiley +1 more source
Angewandte Chemie, EarlyView.Sequence‐diverse meso and “near‐meso” oligourea foldamers are reported and exhibit stimulus‐responsive helix screw‐sense control governed by terminal‐group desymmetrization and sequence‐encoded helix stability. ABSTRACT Meso oligoureas are dynamic hydrogen‐bonded foldamers capable of reversible helix polarity inversion but have so far been limited to ...
Naveen Gupta +13 more
wiley +2 more sources
, 2018 The commonly accepted mechanism of nucleophile-initiated thiol–acrylate reactions requires the formation of undesired nucleophile byproducts. A systematic evaluation of the formation of such nucleophile byproducts has been carried out to understand the ...
Stephen H. Frayne (4269361) +3 more
core +1 more source
Molecular Recognition by Halogen Bonding With Atomic Precision in a Covalent Organic Cage
Angewandte Chemie, EarlyView.A covalent organic cage embedding a single inward‐facing halogen‐bond (XB) donor enables recognition of DMMP, a Sarin surrogate, with atomic precision through halogen bonding, while both the hydrogen bonding donor encaged analogue and the XB donor open model ‐lacking cavity‐ show no affinity.
Pierre‐Antoine Dupin +9 more
wiley +1 more source