Trapping and Characterization of the Reaction Intermediate in Cyclodextrin Glycosyltransferase by Use of Activated Substrates and a Mutant Enzyme [PDF]
, 1997 Cyclodextrin glycosyltransferases (CGTases) catalyze the degradation of starch into linear or cyclic oligosaccharides via a glycosyl transfer reaction occurring with retention of anomeric configuration.
Dijkstra, Bauke W., +4 more
core +3 more sources
Unimolecular Solvolyses in Ionic Liquid: Alcohol Dual Solvent Systems
Molecules, 2016 A study was undertaken of the solvolysis of pivaloyl triflate in a variety of ionic liquid:alcohol solvent mixtures. The solvolysis is a kΔ process (i.e., a process in which ionization occurs with rearrangement), and the resulting rearranged carbocation ...
Elizabeth D. Kochly +2 more
doaj +1 more source
Peptide synthesis by recombinant Fasciola hepatica cathepsin L1 [PDF]
, 2006 Synthesis of the tripeptide Z-Phe-Arg-SerNH2 has been accomplished by a recombinant cysteine protease, cathepsin L1 from liver fluke (Fasciola hepatica), using Z-Phe-Arg-OMe as acyl acceptor and SerNH2 as nucleophile in 0.1 M ammonium acetate pH 9.0–12.5%
Ciarán Ó'Fágáin +16 more
core +1 more source
International Journal of Environmental Health Engineering, 2016 Aims: This research was done to assess the dechlorination and destruction of polychlorinated biphenyls (PCBs) in real-waste transformer oil via microwave (MW) radiation.
Hasan Asilian Mahabadi +2 more
doaj +1 more source
Electrochemical oxidation of clomipramine drug in the absence and presence of 1, 3 dimethyl barbituric acid nucleophile: Electrochemical synthesis of new dibenzazepine derivative [PDF]
شیمی کاربردی روز, 2021 :Electrochemistry due suitable performance (selectivity, speed, sensitivity, and high accuracy) provides very interesting and versatile means for the study of pharmaceutical and biological compounds.
Shahram Lotfi
doaj +1 more source
Structure and stereochemistry of the base excision repair glycosylase MutY reveal a mechanism similar to retaining glycosidases. [PDF]
, 2015 MutY adenine glycosylases prevent DNA mutations by excising adenine from promutagenic 8-oxo-7,8-dihydroguanine (OG):A mismatches. Here, we describe structural features of the MutY active site bound to an azaribose transition state analog which indicate a
Cao, Sheng +6 more
core +2 more sources
HBF4 Catalysed Nucleophilic Substitutions of Propargylic Alcohols [PDF]
, 2015 The activity of HBF4 (aqueous solution) as a catalyst in propargylation reactions is presented. Diverse types of nucleophiles were employed in order to form new C–O, C–N and C–C bonds in technical acetone and in air.
Barreiro, EB +5 more
core +2 more sources
Post-Translational Modification of Proteins Mediated by Nitro-Fatty Acids in Plants: Nitroalkylation
Plants, 2019 Nitrate fatty acids (NO2-FAs) are considered reactive lipid species derived from the non-enzymatic oxidation of polyunsaturated fatty acids by nitric oxide (NO) and related species.
Lorena Aranda-Caño +7 more
doaj +1 more source
Regioselective ring opening of aziridine for synthesizing azaheterocycle
Frontiers in Chemistry, 2023 Aziridine had different regioselective ring openings depending on the functional group of its alkyl substituent. In the case of the alkyl group bearing γ-ketone at the C2 substituent of aziridine, the ring opening by the hydroxy nucleophile from H2O ...
Nikhil Srivastava, Hyun-Joon Ha
doaj +1 more source
Intramolecular pi-pi stacking interactions in 2-substituted N,N-dibenzylaziridinium ions and their regioselectivity in nucleophilic ring-opening reactions [PDF]
, 2009 The ring opening of 2-substituted N,N-dibenzylaziridinium ions by bromide is known to occur exclusively at the Substituted aziridine carbon atom via ail S(N)2 mechanism, whereas the opposite regioselectivity has been observed as the main pathway for ring
Catak, Saron +4 more
core +2 more sources